Showing 76–100 of 192 documents
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Bao Y, Wang C, Xu H, Lai Y, Yan Y, et al.
…ior and quality of prevention and control for pulmonary TB. Trial registration Chinese Clinical Trial Registry ChiCTR2200055557; https://tinyurl.com/4ray3xnw.
Wenwen Sun, Zhengwei Dong, Yiming Zhou, Kunlong Xiong, Hongcheng Liu, et al.
…infection were detected at one time by mNGS. All mNGS-based clinical decisions were made within 2 days.Conclusions The mNGS could accurately and quickly detect fungi and mycobacteria in FFPE specimens from postoperative granuloma specimens and identify the pathogens to the specie…
Kumwichar P, Prappre T, Chongsuvivatwong V
… conversion rates in a 60-day cluster randomized controlled trial with patients with pulmonary tuberculosis (VOT: n=63 and DOT: n=65) with positive sputum acid-fast bacilli smears and 38 observers equally randomized into the VOT and DOT groups (19 observers per group and n=1-5 pa…
Kumwichar P, Chongsuvivatwong V, Prappre T
…se of TB treatment. Methods A cluster randomized controlled trial of pulmonary TB patients and their observers will be conducted over a 2-month period. This study will be conducted in the Hat Yai and Meuang Songkhla districts of Songkhla Province, Southern Thailand. A total of 38…
Zhenfan Wang, Xue Tian, Feng Yang, Lu Wang, Hao Li, et al.
…s under near-infrared imaging. The primary outcomes of this trial were the detection rate and background-tumour ratio of lung nodules, and the secondary objectives were time to search for nodules and operative time to nodules excision. RESULTS: A total of 50 pulmonary nodules in …
Chengyu Jiang, Xiaoqing Luo
…f-management may enhance treatment outcomes in patients. **TRIAL REGISTRATION:** Chinese Clinical Trial Registry, ChiCTR2500096661. Registered 27 January 2025; Retrospectively registered.
He CX, Wu C, Zhang L, Jin HZ
…he need for routine TBI screening and preventive treatment. Trial registration Chinese Clinical Trial Registry, ChiCTR2100045823.
Leon N, Balakrishna Y, Hohlfeld A, Odendaal WA, Schmidt BM, et al.
…ods We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library, MEDLINE Ovid and Embase Ovid in May 2019. We searched Global Health, Ovid and PsycInfo in April 2016. In January 2020 we searched for grey literature in the Grey Literature Repor…
Foster N, Tadesse AW, McQuaid CF, Gosce L, Abdurhman T, et al.
…The ASCENT-Ethiopia study is a three-arm cluster randomised trial assessing two DATs with differentiated care for supporting tuberculosis treatment adherence in Ethiopia. This study is part of the ASCENT consortium, assessing DATs in South Africa, the Philippines, Ukraine, Tanzan…
Tanue EA, Nsagha DS, Theophile NN, Assob JCN
…creasing use of this device. Objective The main aim of this trial is to assess whether sending weekly motivational text messages (SMS) through mobile phones versus no text messaging will improve retention in care and promote adherence to treatment and health outcomes among patien…
Mahasha PW, Ndwandwe DE, Mavundza EJ, Shey M, Wiysonge CS
… of Mycobacterium bovis . Evidence from previous randomised trials show that the efficacy of primary BCG vaccination against pulmonary TB ranged from no protection to very high protection. In addition, some studies suggest a benefit of BCG revaccination. For example, a recent tri…
Nanyunja G, Kadota JL, Namale C, Hudson M, Nalugwa T, et al.
…l protection programs for eligible TB-affected individuals. Trial Registration: Pan African Clinical Trials Registry (PACTR201906852160014).
Pan M, Liu W, Zhang Z, Li T, Xie W
…, providing a reference for the rational use of ciprofol in clinical practice. Methods PTB patients who underwent bronchoscopy examination and treatment at The Third People's Hospital of Changzhou between May 2023 and June 2023 were selected and divided into four groups using a s…
Naomi Chapman, Vinícius Cavalheri, Elizabeth F. Smith, Jamie Wood, Luke W. Garratt, et al.
…utum. METHODS: This was a non-blinded randomised controlled trial where adults hospitalised with a CF exacerbation were allocated to an experimental intervention (EIx; MetaNeb) or a control intervention (CIx; their usual ACT). Both groups underwent twice-daily supervised airway c…
Mouquan Shen, Li Guo, Ya Li, Ruitong Gao, Xin Sui, et al.
…D ANALYSIS: We propose a single-blind randomized controlled trial using 75 hospitalized patients diagnosed with COPD with excessive sputum production. The patients will be divided into three groups. The intervention group will receive active cycle of breathing techniques combined…
Ying Hu, Zhiqiang Chen, Jing Zeng, Shouyan Zheng, Liujuan Sun, et al.
…lls to Tregs under certain conditions. However, no relevant clinical studies have been reported on the association between IDO activity and Th17/Treg imbalance in children with allergic asthma. The goal of this study was to test whether indoleamine 2,3 dioxygenase (IDO) participa…
Imran M, Khan SA, Asdaq SMB, Almehmadi M, Abdulaziz O, et al.
… antituberculosis agents. A few DprE1 inhibitors are in the clinical trial for tuberculosis (TB), including macozinone. This review highlights the discovery, developmental status, clinical studies, patents, and prospects of macozinone (MCZ). The patent and non-patent literature s…
Gashu KD, Gelaye KA, Lester R, Tilahun B
… home. Methods We conducted a two-arm randomised controlled trial on adult patients with TB during the continuation phase. In the intervention arm, patients received routine care plus phone-based weekly pill refilling and daily medication reminders. In the control arm, participan…
Tamuzi JL, Ayele BT, Shumba CS, Adetokunboh OO, Uwimana-Nicol J, et al.
… HIV/TB co-infected or TB patients, screening algorithm and clinical management. Methods We conducted an electronic search of potentially eligible studies published in English in the Cochrane Controlled Register of Trials, PubMed, Medrxiv, Google scholar and Clinical Trials Regis…
Nicola Foster, Amare Worku Tadesse, M Belachew, Mamush Sahlie, Christopher Finn McQuaid, et al.
…fectiveness analysis using data from the cluster randomised trial that evaluated the implementation of labels and pillbox followed by differentiated care to support tuberculosis treatment adherence in 78 health facilities in Ethiopia. We estimated the costs, cost per disability-a…
Amare W Tadesse, Mamush Sahile, Nicola Foster, Christopher Finn McQuaid, Gedion Teferra Weldemichael, et al.
…rrence. **METHODS:** We did a pragmatic cluster-randomised trial in Ethiopia. 78 health facilities (clusters) were randomised (1:1:1) to smart pillbox, medication labels, or standard of care. Adults aged 18 years or older with drug-sensitive pulmonary tuberculosis on a fixed-dos…
Bediang G, Stoll B, Elia N, Abena JL, Geissbuhler A
…between the fifth and the sixth months of treatment. Future trials should focus on reducing the dropout rate. Trial registration The trial was registered on the Pan-African Clinical Trials Registry ( PACTR201307000583416 of 22 July 2013) and the protocol was published.
Jorge D. Machicado, Georgios I. Papachristou
… field of pancreatology, this has translated into increased clinical and research efforts to decrease the burden, morbidity, and mortality associated with benign inflammatory disorders and pancreatic cancer. As a result, there has been a tremendous progress in our understanding o…
Manabu Suzuki, Satoki Hatano, Chie Morita, Akinari Tsukada, Akane Ishida, et al.
…ucted a retrospective observational study to understand the clinical characteristics of patients with cryptogenic hemoptysis (CH). **METHODS:** The clinical characteristics, angiographic findings, and immediate and long-term efficacies of BAE were retrospectively analyzed in 36 …
O'Rourke J, Townsend CL, Milanzi E, Collins IJ, Castro H, et al.
… Methods We searched MEDLINE, Embase, the Cochrane Library, clinical trial registries, reference lists and relevant conferences to identify literature published January 2009-March 2021. We included clinical trials and observational studies assessing the efficacy/effectiveness or …