Showing 76–100 of 184 documents
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Pan Y, Yao Z, Huang L, Xu M, Chen R, et al.
Background Tuberculosis (TB) persists as a global health challenge, with its treatment hampered by the side effects of long-term combination drug therapies and the growing issue of drug resistance. Therefore, the development of novel therapeutic strategies is critical. This study…
Mahin Naderifar, Mahnaz Ghaljeh, Kimiya Sabagh, Bita Amani, Majidreza Akbarizadeh
Background: The differential risk factors associated with extrapulmonary tuberculosis (EPTB) compared to pulmonary tuberculosis (PTB) remain inadequately characterized, particularly in high-burden and culturally distinct settings such as Sistan, Iran. Objectives: This study aimed…
Mbandi SK, Painter H, Penn-Nicholson A, Toefy A, Erasmus M, et al.
Immune reconstitution inflammatory syndrome (IRIS) can be a complication of antiretroviral therapy (ART) in patients with advanced HIV, but its pathogenesis is uncertain. In tuberculosis (TB) endemic countries, IRIS is often associated with mycobacterial infections or Bacille-Cal…
Surya Kant
… elimination and the Revised National TB Control Programme. Vaccines are an effective means of prevention of disease, and TB vaccine development and its current perspectives are briefly discussed in the next chapter. Strategies and guidelines relating to TB infection control and …
Saffar H, Sobhanian P, Alian S, Darvishnia D, Baradaran M
… BD, along with the potential adverse reactions to COVID-19 vaccines in this population, which necessitate special consideration by healthcare professionals.
Pinto Silva, Catarina, de Sousa, Beatriz, Lima, Joana, Vasconcelos, Sofia, Rebelo, Alícia, et al.
Tuberculosis is a challenging diagnosis with marked clinical heterogeneity that can lead to diagnostic delay and serious and potentially life-threatening problems. The most prevalent form of the disease is pulmonary tuberculosis. The present case has unique features as in that it…
Işıl Ezel Taşkın Karaçay, Tuğba Erat, Saliha Kanık Yüksek, Pınar Nalçacıoğlu, Rana Beyoğlu, et al.
To the Editors: Orbital tuberculosis (O-TB) is a rare form of extrapulmonary TB that may mimic neoplasms, inflammatory pseudotumors, or abscesses. Diagnosis relies on microbiology, PCR, histopathology and imaging. Despite challenges, outcomes are favorable with timely antitubercu…
IL Manneh
…rotection limit the development and evaluation of effective vaccines. This thesis addresses two key gaps: (1) the need for non-sputum-based diagnostic tools, and (2) the identification of immune correlates of early protective immunity. Methods: This research was conducted in two …
Loise Maria de Souza Freijanes, Elisa Yuki Kurosawa Ueda, Paola Restum Antonio Lemaitre, Isabela Pierotti Prado
Background: Tuberculous meningitis is the most severe form of M.tuberculosis infection, and occurs when there is an invasion of the membranes and cerebrospinal fluid by the bacteria. It develops as a complication of primary infection and reactivation in immunosuppressed. Objectiv…
Muh. Arfah Syam, Margaretha Solang, Widy Susanti Abdulkadir
Tuberculosis is a disease caused by the bacteria Mycobacterium tuberculosis. Tuberculosis does not only occur in the lungs, which is called pulmonary tuberculosis but can occur outside the lung organs, which is called extrapulmonary tuberculosis. Reinfection from Pulmonary tuberc…
Ubogun Ogheakpobor Efe, Olivia Dutta, Pawan Kumar Garg, Shumaila Zafar
Background: Tuberculosis (TB) is ranked as one of the top 10 causes of death. Mycobacterium tuberculosis (M. TB) infection, the causative organism for TB affects approximately a quarter of the global population placing a burden on the healthcare system. Central nervous system tub…
Chu P, Shi J, Shi J, Dong F, Yang H, et al.
Importance Bacteremia tuberculosis (TB) is a severe form of extrapulmonary TB. Studies assessing bacteremia TB in children are limited, especially for HIV-negative children. Objective To explore the detailed clinical features of the bacteremia TB in children under 18 years of age…
Melgarejo C, Cobos A, Planas C, Fondevila J, Martín M, et al.
… tuberculosis (TB) and are a valid animal model to test new vaccines and treatments to control this disease. In this study, a new experimental model of TB in goats based on the intranasal nebulization of Mycobacterium caprae was assessed in comparison with the endobronchial route…
I. D. Duzhiy, Г.П. Олещенко, Yu.Yu. Shevchenko, M.Yu. Shevchenko, N.V. Yarkova
Objective — to clarify the peculiarities of the course of extrapulmonary tuberculosis to improve its diagnosis by studying the trend of this form of tuberculosis in Sumy region.
 Materials and methods. The structure of the incidence of extrapulmonary tuberculosis of the Sumy…
Billy Zhao, Hyun Jae Kim, Jessica Farrell, Wei Xiong, Jennifer J. Telford, et al.
Introduction:Gastrointestinal tuberculosis (TB) is a rare extrapulmonary manifestation of TB.1 Involvement of terminal ileum, cecum, and peritoneum are more commonly documented while esophageal involvement accounts for less than 0.2% of all TB patients.2-4 Despite the lower incid…
Matheus de Freitas Feitoza, Natália Figueiredo, Mariana Ijano Morsoleto, Nicolle Barbeta da Rosa Gattass, Tamires Cristina Germano
A 25-year-old woman, previously healthy and vaccinated with BCG, developed refractory headache and paroxysmal episodes of loss of consciousness with stereotyped movements. There was a history of occupational exposure to a coworker with respiratory symptoms approximately one month…
Ancuta Bilasco, Ramona Cirt, Szidonia Florea, Anca Cristina Drăgănescu, Magda Vasile, et al.
<h3>Introduction</h3> Even though tuberculosis is considered to be a rare disease in developed countries, Romania is facing an important public health problem despite the fact that every newborn receives a BCG vaccine in maternity. <h3>Case report</h3> We report a case of a 1 yea…
Iker F Garcia Contreras, César A Vega López, Carlos A Gómez Núñez, Ana G Mazier Arita, Alexandra Marquez Carmona
Currently, (MTB) infection remains a major epidemiological health problem in developing countries. Although it primarily involves the lungs, this acid-fast bacillus can disseminate through lymphatic and hematogenous routes. Over the past decades, the incidence of tuberculosi…
Albina Ponosheci Biçaku, Kurtesh Sherifi, Ardian Biçaku, Sadije Namani
**BACKGROUND:** Tuberculous meningitis (TBM) is the most severe manifestation of tuberculosis in children, with high mortality rates and long-term neurological sequelae. Early diagnosis is challenging due to its nonspecific symptoms and insidious onset. **CASE PRESENTATION:** An…
Salim Yusuf, M.D.
Human immunodeficiency virus (HIV) infection puts people at risk of opportunistic infections, such as tuberculosis. In Africa, the HIV epidemic has resulted in an increase in the number of cases of tuberculosis affecting various parts of the body, including the membrane surroundi…
Sailo CV, Tonsing MV, Sanga Z, Chhakchhuak Z, Kharkongor F, et al.
Background Various risk factors of tuberculosis have been studied across the globe, but these may be altered over time and can be specific to geographical regions and there is not much information available from Northeastern region of India. This study aims to investigate the var…
Karl Ekdahl, Norman Begg, Ralf Reintjes, Obaghe Edeghere
Meningitis is the most common cause of meningism; however, meningism can occur in the absence of meningitis It may accompany upper lobe pneumonia, urinary tract infection and other febrile conditions. Cerebrospinal fluid examination is normal in these conditions. Bacterial mening…
Z. K. Ziezoda, K.A. ZAKIROVA, J. M. Yusupjanova, Q. I. Pirov
This article reviews recent publications on tuberculous meningitis. The pathomorphology of the changes, clinical differences from other types of meningitis, diagnostic features of CSF examination and neuroradiological disorders detected by MRI are described. Conclusions. Tubercul…
Rahimi BA, Niazi N, Rahimi AF, Faizee MI, Khan MS, et al.
Background Tuberculous meningitis (TBM) is the most severe form of TB. We prospectively documented the treatment outcomes and the risk factors for death in children with TBM from Kandahar, Afghanistan. Methods This prospective observational cohort study was conducted from Februar…
Yanan Fu, Feng Jiao, Xia Yang, Y. F. Wang, Linzhen Hu, et al.
Severe pulmonary tuberculosis (PTB) drives treatment failure and poor prognosis, analyzing clinical characteristics and risk factors in children is key to early recognition and improving outcomes. A single-center retrospective cohort study of children with PTB in Yunnan, China (2…