Showing 76–100 of 200 documents
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Madzgharashvili T, Salindri AD, Magee MJ, Tukvadze N, Avaliani Z, et al.
Background Among pediatric patients with multidrug-resistant tuberculosis (MDR-TB), limited data exist regarding treatment outcomes in the context of the new and repurposed second-line TB drugs (SLDs). We aimed to describe the treatment outcomes among pediatric MDR-TB patients re…
Dhira Rizki Putri, Marichatul Jannah
…n 2017, Indonesia had 4.950 new cases of HIV infection in pediatrics. In HIV, a chest x-ray is generally used to determine the Opportunistic Infections (OIs) to accelerate treatment. There are differences in the projections and the typical features on chest x-ray in each OI. Th…
Peck GM, Staat MA, Huang FS, Khalil N, Boyce C, et al.
…ad of tuberculosis and the progression to active disease in pediatric patients. As of 2017, the short course combination regimen of weekly isoniazid and rifapentine (3HP) administered by directly observed therapy (DOT) has replaced 9 months of isoniazid as the standard of treatme…
Nicolas A. Menzies, Tyler S. Brown, Jeffrey W. Eaton, Peter J. Dodd, Ted Cohen, et al.
…d dying from tuberculosis (TB). We estimated the additional pediatric TB cases and deaths that could occur over 2025-2034 if programmes supported by United States bilateral health aid and the Global Fund to Fight AIDS, Tuberculosis, and Malaria (Global Fund) are discontinued. Met…
Bineeta Kashyap, Neha Gupta, Pooja Dewan, Puneeta Hyanki, Narendra Singh
… cough, low fever and weight loss. Radiological features in pediatric pulmonary TB may also remain non-specific, most typical being hilar or paratracheal lymphadenopathy. So the diagnosis remains difficult. Microbiological confirmation remains challenging due to suboptimal pulmon…
Bineeta Kashyap, Neha Gupta, Pooja Dewan, Puneeta Hyanki, NarendraPal Singh
… of disease in TBM. We aimed to assess serum TNF-α level in pediatric patients with TB in association with clinicoradiological and microbiological features, with special reference to TBM. Materials and methods Serum TNF-α level was estimated using enzyme-linked immunosorbent assa…
Trim Lajqi, Natascha Köstlin‐Gille, Christian Gille
…in 2020. Particularly, in low- and middle-income countries, pediatric infectious diseases remain a significant public health concern. During early development, infants rely mainly on the activity of the innate immune responses in the defense against invading pathogens. Until rece…
Enrique G. Villarreal, Ricardo J. Estrada-Mendizábal, Emilia Ramos-Barrera, Pablo D Treviño-Valdez, Oscar Tamez‐Rivera
…cal trends of the different clinical presentations of TB in pediatric population. Methods A retrospective, cross-sectional study, carried out at a pediatric referral hospital in Mexico between 2012-2021. Pediatric patients diagnosed with TB were included. Descriptive statistics w…
Sabila Salsabila, Ni Made Mertaniasih, Retno Asih Setyoningrum
…common result on the Xpert MTB/RIF examination in suspected pediatric TB cases. Abstract Introduction: The difficulty of diagnosing tuberculosis (TB) is the most significant challenge in pediatric pulmonary TB cases. More accurate and faster diagnostic tools are essential for det…
Silla Varghese Thomas, Priya Rajendran, Sivakumar Shanmugam
This review provides an insight into pediatric tuberculosis (TB) diagnosis in India. Significant challenges still exist in the accurate diagnosis of pediatric TB due to the paucibacillary status of the bacilli and the nonspecific clinical symptoms. Despite advancements in newer d…
Jeffrey I. Campbell, Thomas J. Sandora, Jessica E. Haberer
…ts to eliminate TB by 2030. Identification and treatment of pediatric LTBI requires completion of a complex care cascade. While attention has been given to LTBI care cascades in adults, to date there has been no attempt to map literature on the pediatric LTBI care cascade. Facili…
Salerno SN, Capparelli EV, McIlleron H, Gerhart JG, Dumond JB, et al.
…tuberculosis co-infection leads to significant mortality in pediatric patients, and treatment can be challenging due to the clinically significant drug-drug interaction (DDI) between lopinavir/ritonavir (LPV/RTV) and rifampin. Doubling LPV/RTV results in insufficient lopinavir tr…
Daniel Mashiach, Justin Shon, Raquel Mashiach, Gregory Ayzenberg, Osnat Barazani, et al.
Pediatric tuberculosis (TB) remains a critically underrecognized contributor to global childhood morbidity and mortality, with the highest burden concentrated in low-resource settings. Although children comprise a minority of overall TB cases, mortality is disproportionately high…
Mi Zhou, Xuren Chen, Jie Huang, Runlin Su, Hongmei Lei, et al.
**BACKGROUND:** Pediatric tuberculosis (TB) management remains an underemphasized area plagued by diagnostic and treatment challenges that are compounded further due to rising levels of drug-resistant tuberculosis (DR-TB). Even though TB incidence is high in China, limited data e…
Golandaj JA
…re an attempt has been made to trace the number of notified Pediatric TB cases during and after COVID-19 lockdown and unlock period, and then compared with the same period of previous year. The epidemic data on notified pediatric TB cases for 2019 and 2020 were extracted from the…
Mohammed Suleiman, Andrés Pérez-López, Ruwa Mohamed, Faheem Mirza, Amina Souli, et al.
…GX-MTB/R) assay, with conventional mycobacterial culture in pediatric non-sputum samples. A total of 417 non-sputum samples from a tertiary pediatric facility underwent simultaneous GX-MTB/R-U and culture testing. Performance was evaluated using conventional culture as a gold sta…
Fekadu G, Bekele F, Bekele K, Girma T, Mosisa G, et al.
…berculosis drugs result in non-adherence to treatment among pediatric patients. Hence, this study was aimed to evaluate pediatrics adherence status among tuberculosis pediatric patients on anti-tuberculosis treatment at Nekemte Specialized Hospital. Methods A health facility-base…
Surve S, Naukariya K, Shah I
…s been reported between 21 and 48%. The exact prevalence of pediatric LTBI in India is still not clear, however, as per few studies, the LTBI prevalence ranges around 40% and 22% in adolescent followed by under-5 population. Studies to fill in the research gap of scarcity of prev…
Jocimar da Silva Santos, Franciely da Costa Alves, Efraim José Dos Santos Júnior, José Lamartine Soares‐Sobrinho, Mônica Felts de La Roca Soares
…nd dapsone. This represents results in lack of adherence in pediatric patients and drug therapy failure, although numerous formulations and technologies have already been developed. AREA COVERED: This study aims to analyze the technological evolution of the pharmaceutical treatme…
Andrea M. Prinzi, Sarah K. Parker, Cary Thurm, Meghan Birkholz, Anna Sick-Samuels
…s of data obtained from the Children's Hospital Association Pediatric Health Information System database between January 1, 2016, through December 31, 2019. Participants were all patients hospitalized with mechanical ventilation aged less than 18 years. Exposures: A charge for an…
Maharaj S, Mungul S, Ahmed S
…l treatment. We have also described the demographic data of pediatric versus adult patients and the predominant age-related subtypes of deep neck space infections. Patients and methods A retrospective review of the data from patients with deep neck space infections during a 5.5-y…
Mandira Chakraborty, Sayani Sardar, Rituparna De, Malabika Biswas, Maria Teresa Mascellino, et al.
…tance patterns of pathogens causing infections in adult and pediatric patients in the ICUs of a tertiary care hospital in Kolkata, India. A cross-sectional, retrospective study was conducted from January 2022 to October 2022 on a total of 139 adult and 146 pediatric patients. Dep…
Campbell J, Sandora T, Haberer J
…ts to eliminate TB by 2030. Identification and treatment of pediatric LTBI requires completion of a complex care cascade. While attention has been given to LTBI care cascades in adults, to date there has been no attempt to map literature on the pediatric LTBI care cascade. Facili…
Juan J. Gómez-Valverde, Ramon Sanchez, José Luis Ribó, H. Simon Schaaf, Lara García Delgado, et al.
…ly those under the age of 5 years. The complex diagnosis of pediatric TB, compounded by limited access to more accurate diagnostic tests, underscores the need for improved tools to enhance diagnosis and care in resource-limited settings. </sec> <sec> <title>OBJECTIVE</title> This…
Fritschi N, Schmidt AJ, Hammer J, Ritz N
Background In Europe, surveillance and monitoring of pediatric tuberculosis (TB) remains important, particularly in the light of migration in recent years. The aim of the study was to evaluate incidence rates of childhood TB and detailed diagnostic pathways and treatment. Methods…