Showing 51–75 of 157 documents
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Singh UB, Verma Y, Jain R, Mukherjee A, Gautam H, et al.
Diagnosis of intra-thoracic tuberculosis (ITTB) in children is difficult due to the paucibacillary nature of the disease, the challenge in collecting appropriate specimens, and the low sensitivity of smear microscopy and culture. Culture and Xpert MTB/RIF provide higher diagnosti…
Lhadon T, Jullien S
Multidrug-resistant tuberculosis (MDR-TB) is a well-identified raising public health concern worldwide. However, the data available on MDR-TB in children and particularly in the neonate age group are limited. Congenital tuberculosis (TB) is rare, and its diagnosis is challenging …
Dinda Nursyafira Misyatin, Arto Yuwono Soeroto, Ferdy Ferdian
Background: Diagnosis of drug-resistant tuberculosis (DR-TB) begins with identifying presumptive DR-TB patients using Xpert MTB/RIF, as a diagnostic test to detect resistance to rifampicin. The study aimed to identify the distribution of rifampicin-resistant tuberculosis (RR-TB) …
Park M, Owles H, Williams A, Williams B, Whittaker E, et al.
Tuberculosis (TB) is an important cause of childhood death and morbidity worldwide. The diagnosis in the pediatric population remains challenging due to the paucibacillary nature of the disease. Intrathoracic lymphadenopathy is one of the most common manifestations of primary dis…
Muhammad Yasin, Nasir Mahmood, Syed Ahmed Saeed Naqvi, Hamid Nisar Khan, Amir Suleman, et al.
Background: The incidence of multidrug-resistant tuberculosis (MDR-TB) is very high in Pakistan considering the fact that Pakistan is one of the few countries with a high burden of tuberculosis – both drug susceptible and drug resistant tuberculosis. Objective: This study focused…
Gita Naidu, Alane Izu, Richard Madimabe, R Wainwright, Stelios Poyiadjis, et al.
…ility to infections including infections with Mycobacterium tuberculosis. Method This prospective study, enrolled children one-19 years old hospitalized for cancer treatment. Screening for M. tuberculosis infection was undertaken by tuberculin skin testing (Mantoux method), and E…
Schaaf HS, Hughes J
Optimal diagnosis and management of children aged <15 y with rifampicin- or multidrug-resistant tuberculosis (RR/MDR-TB) relies on identification of adults with the disease and pro-active screening of their close contacts. Children may be diagnosed with RR/MDR-TB based on microbi…
Tanish Baqar, Sharique Ahmad, Silky Rai
Multiple drug-resistant tuberculosis (MDR-TB) is a critical situation affecting adults as properly as children across the globe (1). To determine the incidence and risk factors associated with Multiple Drug Resistant Tuberculosis (MDR-TB) (2), we studied Ototoxicity on 18 culture…
Carolina Longo, Karina Felippe Monezi Pontes, Marina Matos de Moura Faíco, Mayra Martins Melo, Gustavo Yano Callado, et al.
Tuberculosis remains one of the leading infectious causes of morbidity and mortality worldwide, disproportionately affecting women of reproductive age, particularly in low- and middle-income countries. Tuberculosis during pregnancy represents a major clinical challenge, as physio…
Lumbala Mota Marc, Ilunga Mpoyi Tabitha, Bapu Sapu Rebecca, Cibaka Kabasele Léon, Tabu Yekoli Léonard, et al.
Multidrug-resistant pulmonary tuberculosis (MDR-TB) is an infectious disease whose early diagnosis and management still cause problems in countries with very limited resources. Knowing the great consequences of this disease in the life of an individual, we estimated to make an ep…
Shera Tan, Yee Tang Wang, Hoi Lam She, Kenneth Eng, Ling Kwan, et al.
…healthcare or education. Ten (52.6%) were smear positive at diagnosis. Nine (47.4%) were diagnosed with MDR-TB within two years of their long-term pass approval. Conclusions: There were many missed opportunities for earlier MDR-TB diagnosis among long-term pass holders in Singapo…
M.F. Cissé, Emmanuella Mahugnon Tognimassou, Samba Niang, Fatimata Mbaye, K. Thiam, et al.
Introduction: Despite current progress, tuberculosis remains a major public health problem, given its still high incidence, prevalence, and mortality, particularly in sub-Saharan African countries, including Senegal. This risk is higher for immunocompromised people. Complications…
Ashish Kakar, Abdul Bari Nasar, Ashish Kakar, Ihsan Ul Haq, Riaz Ahmed, et al.
Background: Neurotuberculosis remains a severe manifestation of tuberculosis with high morbidity and mortality, particularly in resource-limited settings. This study aimed to characterize the clinical, diagnostic, and prognostic aspects of neurological complications of tuberculos…
Chiang Mai University
Early diagnosis and appropriate treatment of tuberculous meningitis (TBM) are crucial steps to reduce morbidity and mortality. The WHO recommended to use Xpert MTB/RIF assay to diagnose pulmonary TB, pediatrics TB, extra pulmonary TB and rifampicin resistance. However, the data o…
Samridhi Nigam, Ravendra K. Sharma, Rajiv Yadav, V. G. Rao, Jyothi Bhat
…ucleic Acid Amplification Test (CBNAAT) tests confirmed the diagnosis of M. tuberculosis with Rifampicin resistance. She was promptly initiated on shorter MDR regimen under National TB Elimination Programme (NTEP) and was monitored regularly with successful outcome at the end of …
M. Tukur, Bethrand Odume, M. Bajehson, C. Dimpka, Sani Useni, et al.
…tional centre in the most populous state in Nigeria by KNCV Tuberculosis Foundation Nigeria. Study Design: It was a retrospective review of public health intervention data derived from the mass TB screening of Kano central correctional centre inmates in Kano state, Nigeria. Metho…
Robin Choudhary, Neeraj Sharma, Kunal Kumar, Anmol Sharma
Sir, Tuberculosis is one of the most common infective diseases in the world, and even after decades of research and experience, the diagnosis and management of tuberculosis pose various challenges. The management of drug-sensitive tuberculosis includes the first-line drugs: isoni…
Muhammad Asif Khan, Anwar Ul Haq, Imran Qadir Khattak, Farhan Zeb, Hameed Ullah, et al.
…kground: Since the immune system weakens in people with DM, Tuberculosis is one of the most prevalent infectious diseases . Objective: This study aimed to determine the prevalence of various forms of active Tuberculosis among people with diabetes. Methodology: This Cross-sectiona…
Bangarwa M, Dhingra D, Mittal M, Saigal K, Ghosh A
…ry in the world with almost 27 lakh cases reported in 2019. Pediatric tuberculosis in India accounts for almost 31% of global TB burden. Despite such high mortality and morbidity in children, diagnosis of pulmonary TB in children still remains very challenging. Material and metho…
Taagbara Jolly Abaate, Aloni Alali
…owing global public health concern, and multidrug-resistant Tuberculosis is responsible for roughly one-quarter of all antimicrobial-resistant infection-related deaths worldwide. GeneXpert is a rapid, automated molecular test that detects multi-drug-resistant Tuberculosis using R…
Sekarsari D, Handoyono QF, Amal MY, Maharani MAP, Hendriarto A
…ling a history of contact with parental multidrug-resistant tuberculosis. Multimodality radiological examinations, including conventional radiography, CT, and MRI revealed extensive disease of the spine with disc involvement, large paravertebral abscess, and kyphotic deformity wh…
Tristram D, Tobin EH
Tuberculosis (TB) is an ancient infectious disease with many varied presentations. Although prevention and treatment are available, between 8 and 10 million people still develop TB, and 2 to 3 million people die from it globally, according to the 2022 estimates from the World Hea…
Keri Geiger, Jason E. Farley
…outine HIV viral load (VL) testing at least yearly and upon diagnosis with multidrug-resistant tuberculosis (MDR-TB). Many PWH and MDR-TB in South Africa seem to be missing VL results. This study’s goal was to find results which may be available from the National Health Laborator…
О. М. Raznatovska, Yu. V. Myronchuk, О.S. Shalmin, A.V. Fedorec
Aim. To analyze the course of multidrug-resistant tuberculosis (MDR-TB) in HIV-infected people, depending on the time to COVID-19 diagnosis, using the example of clinical cases from our own observation. Materials and methods. The article presents 3 clinical cases of our own obser…
Pınar Etiz, Ali Tanju Altunsu
…diagnostic methods and treatment outcomes of extrapulmonary tuberculosis cases who were registered to the Adana Tuberculosis Dispensary.Materials and Methods: 400 cases, who were diagnosed with extrapulmonary tuberculosis, treated and followed up between 2014 and 2017, were exami…