Showing 51–75 of 200 documents
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Alejandro Rojas Urrea, Daniela Marino, Ana María Rojas-Faura, Mónica Liseth Holguín Barrera, Lorena García Agudelo
Tuberculosis is known as “the great mimicker.” Extrapulmonary tuberculosis accounts for approximately 20% of all cases, with about 10% of these involving the intestines. The ileocecal region is the most common site due to its high density of lymphoid tissue, slowed intestinal tra…
Bineeta Kashyap, Neha Gupta, Pooja Dewan, Puneeta Hyanki, NarendraPal Singh
Objectives Childhood tuberculosis (TB) accounts for 10–20% of all TB cases, with tuberculous meningitis (TBM) being the leading cause of severe morbidity and mortality. Pathophysiology of TBM still remains obscure. Tumor necrosis factor-α (TNF-α) induces fever and activation of h…
Ana Alice Amaral Ibiapina Parente, Rafaela Baroni Aurílio, Clemax Couto Sant’Anna, Maria de Fátima Bazhuni Pombo Sant’Anna, Afrânio Lineu Kriski, et al.
…uction in the value of the detection limit of Mycobacterium tuberculosis(M. tb.) from 116(from Xpert) to 15.6 CFU. The classification of bacillary load is: high, medium, low, and traces. In Brazil, in children(under 10 years) and in extrapulmonary tuberculosis(EPTB), the result o…
Altynai Zhumabekova
…diagnosed with tuberculous meningitis and miliary pulmonary tuberculosis (TB) during her 16th week of pregnancy. The patient presented with symptoms such as vomiting, severe debilitation, lethargy, and loss of appetite. Chest radiography revealed pulmonary TB with a disseminated …
Tran Thi Van Anh, Phan Viet Hai, Do Thien Hai, Trinh Cuong Loi, Phạm Trung Kiên, et al.
Abstract: Objective: Some factors related to the diagnosis of tuberculous meningitis at the National Children's Hospital (2019 - 2024). Subjects and methods: Cross-sectional descriptive study of 50 children from 1 month to 15 years old diagnosed and treated for tuberculous mening…
Kani Dayal Khare, Krishnendu Maiti
Abstract Tuberculosis secondary affects the genitourinary system, has vague symptoms, and is uncommon in children younger than 3–10 years. Renal thimble bladder (TB) damage, including renal failure and decreased bladder capacity, results from a delayed diagnosis. Here, we will di…
Ayimen Khalid Khan, Shayan Sirat Maheen Anwar, Ashok Kumar, Anam Khan
Tuberculosis of the central nervous system is a deadly disease with a high mortality and morbidity rate. While tuberculosis is prevalent worldwide, most active cases are found in underdeveloped and developing countries, including Pakistan, where it is highly endemic. The pediatri…
Nabaneeta Dash, Maura Manion, Sarah L. Silverberg, Ian Kitai
…nflammatory syndrome (IRIS) observed in people with HIV and tuberculosis (TB) coinfection. In IRIS, there is a clear immune reconstitution event following initiation of antiretroviral therapy (ART), which can lead to a worsening of symptoms of TB that is being treated (“paradoxic…
HarshaV Varma, JayasriH Gali, ArunaK Badam
…ve Identifying the factors responsible for the delay in the diagnosis of tuberculosis (TB). Patients and methods In this retrospective study, data on pulmonary and extrapulmonary forms of TB, registered for the treatment at the directly observed treatment, short course, centre we…
Maloney ME, Cohen B
Importance Tuberculosis (TB) is a significant health concern, affecting over 1.5 million people annually worldwide, with the incidence increasing in the United States from 2020 to 2021. The pediatric population is particularly vulnerable to TB. Extrapulmonary manifestations of TB…
Liza Claire C. Ole, J.L. Lobo, Genelynne J. Beley
…hildren are at increased risk of developing severe forms of tuberculosis (TB) disease. Extrapulmonary tuberculosis (EPTB) contributes significantly to TB-related morbidities. This study aimed to determine patients’ epidemiologic and clinical profile with EPTB among children aged …
Anthony Enimil
…dard. This study reviewed published literature on childhood tuberculosis diagnostic modalities. For childhood tuberculosis (TB) diagnostic modalities, PubMed was searched using Boolean terms OR/AND between childhood tuberculosis and words such as diagnosis, polymerase chain react…
Chen Q, Huang T, Zou L, Jiang L, Sun J, et al.
Background Tracheobronchial tuberculosis (TBTB) is a common form of extrapulmonary tuberculosis that affects the tracheobronchial tree. However, the mechanism has not been fully elucidated. Comparisons of clinical characteristics in various age groups can aid in the understanding…
Isabelle Munyangaju, Lucía Carratalà-Castro, Dulce Osório, Jacob Bigio, Kondwelani John Mateyo, et al.
Diagnosing tuberculosis (TB) in children is challenging due to non-specific symptoms, paucibacillary disease, and difficulty producing sputum. Chest X-rays (CXRs), though widely used, are often inaccessible in low-resource settings and involve radiation. Ultrasound (US) is a radi…
Howal Prashant, Sahu Saloni, Ganiyani Mohammad Arfat
Tuberculosis (TB) is a highly infectious disease with high prevalence in the economically poor countries in the world with pulmonary and extrapulmonary manifestations. Though major involvement is pulmonary but extrapulmonary tuberculosis burden is quite high & requires a very…
Haiqiong Chen, Shi Gao, Li Li, Xufei Zhao, Guoqiang Zhao
Extrapulmonary tuberculosis is relatively rare, and osteoarticular tuberculosis involving the ankle joint is particularly uncommon. We report a 10.5-year-old, previously healthy male patient who initially presented to the trauma surgery department with a 2-month history of swelli…
L Fidelle, Raman Mahajan, J Gallo, E Biague, Ramiro Gonçalves, et al.
BACKGROUND AND OBJECTIVES Over half of childhood tuberculosis (TB) remains undiagnosed yearly. TB culture is often unavailable. WHO recommends Xpert-Ultra as first test for diagnosis of paediatric TB, but microbiological confirmation remains low and often requires invasive proced…
Mariana Sá Pinto, Marta Barros, Joana Da Silva Fernandes
Ocular tuberculosis is a clinical challenge due to heterogeneous presentation and difficulty in obtaining ocular samples for microbiology. The incidence is difficult to specify because it is almost exclusively a presumptive diagnosis based on epidemiology and concordant ophthalmo…
Chen Y, Fan L, Ren Z, Yu Y, Sun J, et al.
… next-generation sequencing (tNGS) enables high-performance tuberculosis (TB) diagnosis and drug resistance prediction directly from clinical samples. However, its applicability to paucibacillary TB, including pediatric TB and extrapulmonary TB (EPTB), has been less explored. We …
MinaS Boshra, MohamedS ElBouhy, Hesham Atef AbdelHalim
Background Extrapulmonary tuberculosis (EPTB) is more common than pulmonary tuberculosis (PTB) in Assuit Chest Hospital.Objective To know the prevalence of EPTB in comparison to PTB in Assiut Chest Hospital.Methods An 18-month retrospective descriptive analysis to assess the prev…
S Sinha, A Ajayababu, R Titiyal, A Sinha, P R Mohapatra, et al.
Abstract Background Extrapulmonary tuberculosis (EPTB) constituting approximately one-fifth of the overall burden of tuberculosis (TB), is challenge both in terms of diagnosis due to lower rates of microbiological positivity and for treatment in terms of drug penetration, duratio…
Hakim A, Komaratih E, Zuhria I
Ocular tuberculosis in children poses significant visual risks and exhibits distinct characteristics compared to adults, necessitating careful diagnosis and management. This case illustration presents a 10-year-old girl with intermittent redness in her left eye. Despite initial t…
Sevgi Yaşar Durmuş, Gönül Tanır, Ayşe Seçil Ekşioğlu, Türkan Aydın Teke, Yasemin Taşçı Yıldız, et al.
Objective: Abdominal tuberculosis is a kind of extrapulmonary tuberculosis that can usually occur during the lymphohematogenous spread of first Mycobacterium tuberculosis infection, develop by neighborhood from an abdominal focus or a mesenteric lymph node. The aim of this study …
Sevgi Yaşar Durmuş, Gönül Tanır, Ayşe Seçil Ekşioğlu, Türkan Aydın Teke, Yasemin Taşçı Yıldız, et al.
Objective: Abdominal tuberculosis is a kind of extrapulmonary tuberculosis that can usually occur during the lymphohematogenous spread of first Mycobacterium tuberculosis infection, develop by neighborhood from an abdominal focus or a mesenteric lymph node. The aim of this study …
Ortiz GJ, Delgado J, Ramírez T, Galeano MA, Barnafi N, et al.
Osteoarticular tuberculosis (TB) is an uncommon form of extrapulmonary TB that has the potential to damage joints and bones, generating long-term impairment. Mainly, the initial diagnosis of osteoarticular TB relies on clinical findings and imaging. When required, imaging can aim…