Showing 26–50 of 200 documents
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Yu S, Gao Y, Lu J, Zhang G, Chen X, et al.
…elated factors linked to the development and infectivity of tuberculosis. This was achieved by comparing the clinical characteristics of patients with pulmonary tuberculosis (TB) who tested positive in smear Mycobacterium tuberculosis tests with this who tested negative in smear …
Molla Y, Wubetu M, Dessie B
Background Tuberculosis caused by susceptible mycobacterium tuberculosis strains is effectively treated by the first-line anti-tuberculosis drugs. However, most antibacterial drugs are known to induce hepatotoxicity which may limit their adherence and hence lead to the developmen…
Retno Budiarti, Ediono Ediono, Ni Made Mertaniasih, Soedarsono Soedarsono
Diagnosis of active tuberculosis (TB) is the first step to determine the next treatment management of patient care. The success of the treatment will not be achieved without the determined accurate diagnosis rapidly. The definitive diagnosis of tuberculosis includes the presence …
Olbrich L, Verghese VP, Franckling-Smith Z, Sabi I, Ntinginya NE, et al.
Background Childhood tuberculosis remains a major cause of morbidity and mortality in part due to missed diagnosis. Diagnostic methods with enhanced sensitivity using easy-to-obtain specimens are needed. We aimed to assess the diagnostic accuracy of the Cepheid Mycobacterium tube…
Oshima K, Nakajima C, Hirata K, Hayashi H, Kodama EN, et al.
Tuberculosis remains a major public health concern. Millions of tuberculosis cases and associated deaths have been reported worldwide. The Indo-Oceanic lineage Mycobacterium tuberculosis is common in Southeast Asia and causes extrapulmonary lesions. Only a few case studies on thi…
Md Mayin Uddin Hasan, Mohammad Injamul Hoq, Saifur R Chowdhury
**BACKGROUND:** Tuberculosis remains one of the primary infectious diseases in Bangladesh that affects both adults and children. Poor diagnostic criteria and insufficient reporting, especially of pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) in children, lim…
Abiodun Ronke Ojewuyi, Abiona Oluwadamilola Odeyemi, A.O. Odeyemi, Amadin Aitua Olotu
Abstract Background Tuberculosis (TB) is a cause of high morbidity and mortality across the world but more so in developing countries. A large proportion of patients with tuberculosis present with extra-pulmonary disease which is often misdiagnosed or under-diagnosed. In Southwes…
Wanli Kang, Jiajia Yu, Cheng Liang, Quanhong Wang, L. Li, et al.
…le>Abstract</title> <bold>Background: </bold>Extrapulmonary tuberculosis (EPTB) is a significant health problem which can lead to severe morbidity and mortality. In clinical practice, EPTB can have a variety of nonspecific clinical manifestations and can be concurrent with other …
Anak Agung Fendy Triwicaksana, Musofa Rusli, Muhammad Vitanata Arfijanto, Bramantono, Nasronudin Nasronudin, et al.
…ing to some infections such as pulmonary and extrapulmonary tuberculosis. A rare case of decreased CD4+ T cells is idiopathic CD4+ T cell lymphocytopenia, a rare and unexplained immunodeficiency syndrome with no evidence of HIV infection. In this case report, we are reporting a p…
Amare W Tadesse, Noriah Maraba, Jason Alacapa, Katya Gamazina, Tanyaradzwa Dube, et al.
**BACKGROUND:** Tuberculosis remains a leading cause of death globally, particularly in countries with high tuberculosis and HIV burdens. Disruptions caused by the COVID-19 pandemic may have further impacted tuberculosis outcomes. This study examines on-treatment mortality and as…
Jiajia Yu, Yunqing Chang, Chen Liang, Shengsheng Liu, Liang Li, et al.
Extrapulmonary tuberculosis (EPTB) is a significant health problem which can lead to severe morbidity and mortality. In clinical practice, EPTB can have a variety of nonspecific clinical manifestations and can be concurrent with other types of EPTB. As information pertaining to c…
Ekaterina Kulchavenya, Mahmadzarif Merganov
Introduction: The role of extrapulmonary tuberculosis (EPTB) in general and urogenital tuberculosis (UGTB) in particular is under-estimated in official statistics, medical practice and by the population. The purpose of this report was to estimate the relative importance of UGTB i…
Neelam Chauhan, Anshu Sharma
Tuberculosis (TB) and HIV have been closely linked since the emergence of AIDS. Worldwide, TB is the most common opportunistic infection affecting HIV-seropositive individuals and it remains the most common cause of death in patients with AIDS. Aim is to determine the percentage …
Vandana Balgi, J Sanjana, D K Suneetha, Amrudha Surendran, Gowri Chandrashekar
Background: Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which has posed a constant challenge to mankind in its treatment due to increasing resistance and longer duration of treatment. The newer approach is to look towards strengthening host immune …
Aishwarya Alavandar
Background: Standard weight-based dosing of first-line anti-tuberculosis drugs does not consistently achieve therapeutic plasma concentrations in all patients. Inadequate drug exposure may contribute to poor treatment response, particularly in extrapulmonary and disseminated tube…
P. K. Yаblonskiy, B. I. Vishnevskiy, N. S. Solovyova, Vladimir Galkin
…ive: to assess changes in the data on drug resistance of M. tuberculosis for 2015-2021 and compare it with data for 2012-2014. Subjects and Methods. Using continuous sampling, the frequency of drug resistance of Mycobacterium tuberculosis (MTB DR) was studied in isolates from 151…
Надежда Игоревна Поркулевич, А. В. Мордык
…trend towards a decrease in the incidence of extrapulmonary tuberculosis is noted both in the Omsk region and throughout the Russian Federation Purpose of the study. To study anamnestic, epidemiological and clinical features of children diagnosed with renal tuberculosis and other…
Y Hafeeza, M Rishitha, Naga Yeseswini S, Venu Babu A, Sumavi Sekhar J, et al.
Background: Tuberculosis is a global disease leading to cause death worldwide. The Revised National Tuberculosis Control Programme (RNTCP), Directly Observed Treatment Short Course (DOTS), was launched to reduce tuberculosis mortality, improve patient adherence to treatment, and …
Rupali Rupali, Karan Sharma, N. C. Kajal
…lass="abstract"><strong>Background:</strong> Tuberculosis (TB) is primarily a disease of lungs but can affect any part of the body. Among extrapulmonary TB, tuberculosis of otorhinolaryngeal region is uncommon but not rare. Despite the best efforts of the RNTCP, tu…
Ayik R. Puspaningtyas, Ari S. Nugraha, Yuni Retnaningtyas, Siti Zulaiha
Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb). Mtb affects not only the respiratory system but also other body organs, such as the lungs, leading to pulmonary and extrapulmonary TB, the brain, and the spine. Aspilia pluriceta from Me…
Abhishek S, Saikia UN, Gupta A, Bansal R, Gupta V, et al.
Background: Intraocular tuberculosis (IOTB), an extrapulmonary manifestation of tuberculosis of the eye, has unique and varied clinical presentations with poorly understood pathogenesis. As it is a significant cause of inflammation and visual morbidity, particularly in TB endemic…
van Leeuwen LM, Versteegen P, Zaharie SD, van Elsland SL, Jordaan A, et al.
…itis (TBM), the most severe extrapulmonary manifestation of tuberculosis, is caused by the pathogen Mycobacterium tuberculosis The M. tuberculosis complex includes seven lineages, all described to harbor a unique geographical dissemination pattern and clinical presentation. In th…
Alavandar A
Background Standard weight-based dosing of first-line anti-tuberculosis drugs does not consistently achieve therapeutic plasma concentrations in all patients. Inadequate drug exposure may contribute to poor treatment response, particularly in extrapulmonary and disseminated tuber…
Safira Amelia, Nastiti Kaswandani
Background: Tuberculosis remains a significant cause of mortality in children. Nutritional status is one of the major risk factors for tuberculosis severity. This study investigated the factors influencing nutritional status in tuberculosis patients. Methods: This is a retrospect…
Aishwarya Alavandar
…CKGROUND:** Standard weight-based dosing of first-line anti-tuberculosis drugs does not consistently achieve therapeutic plasma concentrations in all patients. Inadequate drug exposure may contribute to poor treatment response, particularly in extrapulmonary and disseminated tube…