Showing 26–50 of 200 documents
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Jin Yin, Min Yu
**BACKGROUND:** For bacteriologically negative suspected tuberculosis, immunological testing provides important diagnostic evidence. The traditional tuberculin skin test has poor specificity. QuantiFERON-TB Gold Plus (QFT-Plus, the latest generation of Interferon-Gamma Release As…
Onya Opota, René Brouillet, Gilbert Greub, Katia Jaton
OBJECTIVES: In order to cope with the rapid spread of the COVID-19 pandemic, we introduced on our in-house high-throughput molecular diagnostic platform (MDx Platform) a real-time reverse transcriptase PCR (RT-PCR) to detect the SARS-CoV-2 from any clinical specimens. The aim of …
Udalamaththa Gamage Gihan Chamind, Krishantha Wickramasekara Rajapaksha Wimalagunarathne, H.L.S. Chathurika M.C. Mudannayake, Sunil De Alwis
Tuberculosis (TB) is prevalent in Sri Lanka and poses a considerable public health issue, even though the country is categorized as having a low burden of the disease.It ranks as the second most significant infectious disease in Sri Lanka, with around 500 to 600 fatalities each y…
Johansen ØH, Abdissa A, Zangenberg M, Mekonnen Z, Eshetu B, et al.
Background Cryptosporidiosis is a common cause of diarrhoea in young children (aged younger than 24 months) in low-resource settings but is currently challenging to diagnose. Light-emitting diode fluorescence microscopy with auramine-phenol staining (LED-AP), recommended for tube…
Li L, Wang Y, Zhang R, Liu D, Li Y, et al.
Patients with tuberculous pleurisy often remain undiagnosed even after blind thoracentesis and closed pleural biopsy (PB). In this study, we assessed the value of computed tomography (CT)-guided core needle biopsy of pleural lesion and evaluated the diagnostic accuracy of polymer…
Ahmadul Hasan Khan, Shakila Yeasmin, Sanjida Anjum, F Haque
Abstract Background Provision of early and accurate Tuberculosis (TB) diagnosis is crucial to end TB specially in a densely populated like Bangladesh. Molecular WHO-approved rapid diagnostic tests for TB (mWRDs) can significantly improve identification of undiagnosed TB cases. Th…
Himanshu Jha, Chandra Prakash Baveja, Vinay Kamal, Prem Narayan Agarwal, Sonal Saxena, et al.
Background and Objectives . Tuberculosis has become a major health problem in India, and the incidence of tuberculous lymphadenitis (TBLN) has increased in parallel with the increase in the incidence of mycobacterial infection worldwide. Therefore, the main objective of this stud…
Wood RC, Luabeya AK, Dragovich RB, Olson AM, Lochner KA, et al.
Tongue dorsum swabbing is a potential alternative to sputum collection for tuberculosis (TB) testing. Previous studies showed that Cepheid Xpert MTB/RIF Ultra (Xpert Ultra) can detect Mycobacterium tuberculosis DNA on tongue swabs stored in buffer, with 72% sensitivity and 100% s…
Jin Ma, Lu Qi, Shan Tung Tu, Xiaoyan Miao, Juan Zhao
Background: Respiratory tract infection (RTI) is one of the most common diseases worldwide, and its incidence is rising year by year due to environmental pollution. Sputum culture remains the gold standard for RTI diagnosis, but its performance is limited by difficulties related …
Daniel Mukadi‐Bamuleka, Junior Bulabula-Penge, Bart K. M. Jacobs, Anja De Weggheleire, François Edidi-Atani, et al.
BACKGROUND: Ebola virus disease (EVD) outbreaks have emerged in Central and West Africa. EVD diagnosis relies principally on RT-PCR testing with GeneXpert®, which has logistical and cost restrictions at the peripheral level of the health system. Rapid diagnostic tests (RDTs) woul…
Sood M, Sharma S, Sood S, Sharma V
Tuberculosis is predicted to be a major undocumented cause of mortality in children. This systematic review with meta-analysis assessed the diagnostic accuracy of Lipoarabinomannan antigen testing (FujiLAM) in urine in HIV-negative children with TB-like signs and symptoms. PubMed…
Mahato RP, Kumar S
Tuberculosis (TB) is still the most frequent cause of morbidity and mortality in the world caused by Mycobacterium tuberculosis (MTB). Due to slow diagnostic and treatment options, the disease is a major concern for public health and also increases the burden on the global econom…
Luana Michelly Aparecida da Costa, Filipe Andrade Bernardi, Tiago Lara Michelin Sanches, Afrânio Lineu Kritski, Rafael Mello Galliez, et al.
…ee sharply the whole flow of processes in order to evaluate diagnostics cascades. Based on that, first, we developed a design of tuberculosis system operations in discrete-time based model, then we made a description of an agent-based transmission model developed to be incorporat…
Zhao X, Cui K, Bai L, Xu S, Liu W, et al.
This study aimed to evaluate the diagnostic value of rapid simultaneous RNA amplification and testing for tuberculosis (SAT-TB) in smear-negative pulmonary tuberculosis (PTB). We performed a multicenter prospective analysis of 206 patients with smear-negative suspected PTB betwee…
Moreira FMF, Verma R, Pereira Dos Santos PC, Leite A, da Silva Santos A, et al.
Background There is a need to identify scalable tuberculosis screening strategies among high burden populations. The WHO has identified a non-sputum-based triage test as a development priority. Methods We performed a diagnostic case-control study of point-of-care C-reactive prote…
Lu Zhang, Frederick L Altice, Adeeba Kamarulzaman, Ahsan Ahmad, Sangeeth Kaur, et al.
**BACKGROUND:** The World Health Organization (WHO) recommends tuberculosis (TB) screening in prisons but data on specific strategies are lacking. **METHODS:** Men sequentially entering Kajang Prison, Malaysia's largest prison, underwent standardized WHO symptom screening (SS), …
Nathavitharana, Ruvandhi, Pearl, Abarna, O’Bryan, Matthew, Edwards, Matthew, van der Westhuizen, Helene-Mari, et al.
World Health Organization
McDowell, Andrew, Anjorin, Omolayo, van der Westhuizen, Helene-Mari, Engel, Nora, Subramanian, Advaith, et al.
Kehongo Moses Nyanguru, Ephantus G. Ndirangu, Robi Chacha, Bakari Chaka, J. O. Moody, et al.
Background: Tuberculosis (TB) remains a significant global health burden, exacerbated by increasing multidrug resistance. Medicinal plants, such as Albizia zygia (DC.) J.F. Macbr, is being used in Kenya to manage TB symptoms; however, antimycobacterial potential remains scientifi…
Fatma Z Kamel, Nagwan Adel Ismail, Asmaa Z Khater, Alia A El Shahawy, Noura Almadani, et al.
Tuberculosis and sarcoidosis can present with similar clinical and radiological features, especially intrathoracic lymphadenopathy, complicating differential diagnosis. This study explored the potential utility of QuantiFERON-TB Gold (QFT), serum High Mobility Group Box 1 protein…
Zhou Y, Lin P, Xia L, Heidari AA, Chen Y, et al.
Talaromycosis (TSM) affects immunocompromised individuals, particularly those with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), causing varied pulmonary abnormalities on chest computed tomography (CT). These features overlap with pulmonary tubercu…
Elsohaby I, Alahadeb JI, Mahmmod YS, Mweu MM, Ahmed HA, et al.
The aim of the present study was to calculate the sensitivity (Se) and specificity (Sp) of the single cervical tuberculin test (SCT), rapid lateral flow test (RLFT), and real-time polymerase chain reaction (RT-PCR) for the diagnosis of Mycobacterium bovis ( M. bovis ) infection i…
David Branigan, Claudia M. Denkinger, Jennifer Furin, Petra Heitkamp, Stijn Deborggraeve, et al.
… and link more people to testing with WHO-recommended rapid diagnostics.7Stop TB PartnershipThe introducing new tools project.https://www.stoptb.org/accelerate-tb-innovations/introducing-new-tools-projectDate accessed: May 16, 2023Google Scholar, 8Marks GB Horsburgh Jr, CR Fox GJ…
Biswajit Chakraborty, Amaj Laskar, Vipin Kumar, Zeeshan M Khan, Remesh Kumar, et al.
…iagnostic accessibility, WHO introduced the first Essential Diagnostics List (EDL) in 2018, providing a global framework for cost-effective and accurate diagnostics for critical diseases, including neglected tropical diseases (NTDs). Building on this, several countries are develo…