Showing 1–25 of 200 documents
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Cox H, Salaam-Dreyer Z, Goig GA, Nicol MP, Menardo F, et al.
…ound South Africa has a high burden of rifampicin-resistant tuberculosis (including multidrug-resistant [MDR] tuberculosis), with increasing rifampicin-monoresistant (RMR) tuberculosis over time. Resistance acquisition during first-line tuberculosis treatment could be a key contr…
Andarge DB, Anticho TL, Jara GM, Ali MM
Objective Multidrug-resistant Mycobacterium tuberculosis is a public health threat in resource-limited countries where it is easily disseminated and difficult to control. The aim of this study was to determine the prevalence of tuberculosis, rifampicin-resistant/multidrug-resista…
Wubu B, Jemal M, Million Y, Gizachew M
…r areas are important sites for disseminating Mycobacterium tuberculosis among individuals living in such areas. This study examined patients with suspected pulmonary tuberculosis (PTB) visiting the Abrihajira and Metema hospitals in northwest Ethiopia to investigate the prevalen…
Jorwal P, Singh BK, Anand A, Khan F, Khandelwal K, et al.
Background Tuberculosis (TB) is still the second causative agent of death worldwide after COVID-19. It is caused by Mycobacterium tuberculosis (MTB) infection. Objective The aim of the current study was to compare the performance of GeneNAT real-time polymerase chain reaction ana…
Dejene TA, Hailu GG, Kahsay AG, Wasihun AG
Introduction Tuberculosis (TB) is the second leading cause of mortality from an infectious disease worldwide. Multidrug-resistant tuberculosis (MDR-TB), where rifampicin-resistant TB is the biggest contributor, remains a global health threat. There is scant data on MTB and rifamp…
Téllez-Navarrete NA, Ramon-Luing LA, Muñoz-Torrico M, Preciado-García M, Medina-Quero K, et al.
Background Tuberculosis (TB) is an infectious disease. During TB, regulatory T cells (Treg) are related to poor prognosis. However, information about conventional and unconventional Treg (cTreg and uTreg, respectively) is limited. The tumour necrosis factor (TNF) and its receptor…
Sulistijawati RS, Icksan AG, Lolong DB, Nurwidya F
Background Tuberculosis (TB) remains a burden globally, including Indonesia. The primary objective of this study is to reveal the chest radiography characteristic of drug-sensitive TB (DS-TB) and multi-drug resistant TB (MDR-TB) in the Indonesian national tuberculosis prevalence …
Sinshaw W, Kebede A, Bitew A, Tesfaye E, Tadesse M, et al.
…ted risk factors among presumptive smear negative pulmonary tuberculosis patients in Addis Ababa, Ethiopia. Methods Analytic cross sectional study design was used. A total of 418 smear negative presumptive pulmonary TB patients were enrolled from selected health facilities since …
Erkihun M, Kiros T, Berhan A, Ayele B
Introduction. Multi-drug-resistant tuberculosis (MDR-TB) is an emerging global challenge. Ethiopia is one of the 20 top countries with the highest estimated numbers of incidents of MDR-TB. Recently, the World Health Organization warned that drug-resistant TB is escalating and cal…
Nalunjogi J, Mucching-Toscano S, Sibomana JP, Centis R, D'Ambrosio L, et al.
…s growing on the overall impact of the COVID-19 pandemic on tuberculosis (TB) services, global studies based on national data are needed to better quantify the extent of the impact and the countries' preparedness to tackle the two diseases. The aim of this study was to compare th…
Yao S, Yan J, Li L, Ma D, Liu J, et al.
Background Multidrug-resistant tuberculosis (MDR-TB) is currently a major problem in China. The prevention and treatment work for MDR-TB patients started late in Anhui province. To determine the prevalence of MDR-TB in sputum smear-positive TB patients (SSPTBPs) and analyze the r…
Ogwang MO, Imbuga M, Ngugi C, Mutharia L, Magoma G, et al.
Introduction Globally anti-tuberculosis drug resistance is one of the major challenges affecting control and prevention of tuberculosis. Kenya is ranked among 30 high burden TB countries globally. However, there is scanty information on second line antituberculosis drug resistanc…
Engel N, Ochodo EA, Karanja PW, Schmidt BM, Janssen R, et al.
…kground Programmes that introduce rapid molecular tests for tuberculosis and tuberculosis drug resistance aim to bring tests closer to the community, and thereby cut delay in diagnosis, ensure early treatment, and improve health outcomes, as well as overcome problems with poor la…
Gebremariam G, Kiros M, Hagos S, Hadush H, Gebremichael A, et al.
Background Tuberculosis (TB) is a major public health concern in the developing countries. Moreover, the emergence of multidrug-resistant tuberculosis is challenging. However, there are no organized data on the trends of pulmonary tuberculosis and rifampicin-resistant Mycobacteri…
Ali MM, Weldegebreal F, Kabew G, Urgesa K
Background Multi-drug resistant Mycobacterium tuberculosis is a growing public health problem in developing countries including Somalia. Although, the prevalence of multi-drug resistant tuberculosis among new and retreated cases is high, data on GeneXpert- Mycobacterium tuberculo…
Vyawahare C, Mukhida S, Khan S, Gandham NR, Kannuri S, et al.
Introduction Tuberculosis remains a global health problem worldwide and the risk progression of Tuberculosis to Drug Resistant Tuberculosis is influenced by various factors. These include immunocompromised status, past history of tuberculosis, life style and nutritional level. He…
Ayenew Berhan, Bekele Sharew, Andargachew Almaw, Shewaneh Damtie, Biruk Legese, et al.
**BACKGROUND AND AIMS:** Tuberculosis is a major infectious disease that affects hematological profiles. However, limited data assess changes in hematological profiles among patients with pulmonary and multidrug-resistant tuberculosis. Therefore, this study aimed to compare the h…
Tierney DB, Orvis E, Nathavitharana RR, Hurwitz S, Tintaya K, et al.
…ly, Separate safely, Treat effectively) strategy on time to tuberculosis diagnosis and treatment for patients at a general hospital in a tuberculosis-endemic setting. Design Prospective cohort study with historical controls. Participants Patients diagnosed with pulmonary tubercul…
Merid Y, Hailu E, Habtamu G, Tilahun M, Abebe M, et al.
Introduction Understanding the epidemiology of tuberculosis is limited by lack of genotyping data. We sought to characterize the drug susceptibility testing patterns and genetic diversity of M. tuberculosis isolates in southern Ethiopia. Methodology A cross-sectional study was co…
Ali S, Khan MT, Khan AS, Mohammad N, Khan MM, et al.
Anti-tuberculosis therapy involves the combination of drugs to hamper the growth of Mycobacterium tuberculosis (MTB). The emergence of multidrug-resistant tuberculosis (MDR-TB) is a global concern. Pakistan has been ranked 5 th position in terms of a high burden of MDR-TB in the …
Nindrea RD, Sari NP, Harahap WA, Haryono SJ, Kusnanto H, et al.
… data presents a survey data describing multidrug-resistant tuberculosis, tuberculosis patients characteristics and stress resilience during COVID-19 pandemic in West Sumatera Province, Indonesia. The data were gathered from multidrug-resistant tuberculosis, tuberculosis patients…
Djika M, Koudokpon CH, Dougnon VT, Sanoussi N, Alphazazi S, et al.
Introduction tuberculosis remains a major public health problem, with continuing high levels of prevalence, and mortality. In Niger, the incidence of tuberculosis remains high. This study aims to investigate the epidemiology of pulmonary tuberculosis at the National Anti-Tubercul…
Kahase D, Desta K, Yaregal Z, Yenew B, Driba G, et al.
…ing Ethiopia. Hence, we aimed to assess the magnitude of M. tuberculosis and nontuberculous mycobacteria (NTM) among presumptive pulmonary tuberculosis patients attending St. Paul's hospital Medical College, Addis Ababa, Ethiopia. Methods A cross-sectional study was conducted fro…
Tembo BP, Malangu NG
…iated with the prevalence of multidrug/rifampicin-resistant tuberculosis among suspected drug resistant tuberculosis patients in Botswana. Methods A retrospective review of medical records of suspected drug resistant tuberculosis patients receiving care at public health facilitie…
Li X, Sheng L, Tu J, Lou L
…o determine the bactericidal effect of nano silver and anti-tuberculosis drugs on drug-resistant Mycobacterium tuberculosis . Solid-state drug sensitivity tests with streptomycin (SM), isoniazid (INH), RIF, EMB, kanamycin (km), and ofloxacin (ofx) were carried out on H37Rv and di…