Showing 1–25 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Pereira AHB, Lopes CAA, Pissinatti TA, Pinto ACA, Oliveira DRA, et al.
… pathology of monkeys naturally infected with Mycobacterium tuberculosis complex from five different colonies in Rio de Janeiro, Brazil. On the basis of gross and histopathological findings, the lesions were classified into chronic-active, extrapulmonary, early-activation or late…
Scherer J, Mukasa SL, Wolmarans K, Guler R, Kotze T, et al.
Background Tuberculosis (TB) is one of the top ten causes of death worldwide, with approximately 10 million cases annually. Focus has been on pulmonary TB, while extrapulmonary TB (EPTB) has received little attention. Diagnosis of EPTB remains challenging due to the invasive proc…
Sun JM, Wang C, Jin DQ, Deng F
Congenital tuberculosis (TB) is rare and the prognosis is poor if not detected early. The diagnosis is often delayed owing to non-specific clinical presentation, misdiagnosis and undiagnosed maternal TB during pregnancy. A 12-day-old girl presented with a 5-day history of fever, …
Van Hoving DJ, Griesel R, Meintjes G, Takwoingi Y, Maartens G, et al.
Background Accurate diagnosis of tuberculosis in people living with HIV is difficult. HIV-positive individuals have higher rates of extrapulmonary tuberculosis and the diagnosis of tuberculosis is often limited to imaging results. Ultrasound is such an imaging test that is widely…
Menzies NA, Quaife M, Allwood BW, Byrne AL, Coussens AK, et al.
Background Many individuals who survive tuberculosis disease face ongoing disability and elevated mortality risks. However, the impact of post-tuberculosis sequelae is generally omitted from policy analyses and disease burden estimates. We therefore estimated the global burden of…
K Monisha, Siddlingappa Hugara, K M Nanditha
**BACKGROUND:** National Tuberculosis Elimination Programme focuses more on open (pulmonary) cases of tuberculosis. In addition to pulmonary tuberculosis, extrapulmonary tuberculosis cases also contribute to the tuberculosis burden and spread of infection among household contacts…
Hu SS, Wei QC, Wu Y, Li XN, Liu FJ, et al.
Background Extrapulmonary tuberculosis (TB) is a relatively rare form of tuberculosis infection, accounting for approximately 15% of all tuberculosis infections. Lymph nodes are the most commonly affected sites, while involvement of the parotid gland is extremely rare. Case prese…
Xu-Wen Fu, Yan Bi, Min Qi, Jing-Liang Liu, Jia-Lu Wei, et al.
…m of this study is to enhance the understanding of prostate tuberculosis by analyzing clinical data and prostate computed tomography (CT) imaging of patients with hematogenous disseminated pulmonary tuberculosis and prostate tuberculosis. **METHODS:** Patients with hematogenous …
Avkan-Oğuz V, Öner-Eyüboğlu F, Turunç T, Ersöz G, Tezer-Tekçe Y, et al.
Objectives Tuberculosis risk in solid-organ transplant recipients is more than the general population, although tuberculosis incidence has been reported to decrease 5% in the last decade in Turkey. In Turkey, solid-organ transplants started in 1975; however, routine pretransplant…
Paudel D, Shrestha SL
Introduction Tuberculosis outside of the lung is extrapulmonary tuberculosis. The diagnosis of extrapulmonary tuberculosis is not easy in a community setting even in district hospitals. Clinical symptoms and radiological diagnosis are effective for the diagnosis of pulmonary and …
Yu S, Gao Y, Lu J, Zhang G, Chen X, et al.
…elated factors linked to the development and infectivity of tuberculosis. This was achieved by comparing the clinical characteristics of patients with pulmonary tuberculosis (TB) who tested positive in smear Mycobacterium tuberculosis tests with this who tested negative in smear …
Molla Y, Wubetu M, Dessie B
Background Tuberculosis caused by susceptible mycobacterium tuberculosis strains is effectively treated by the first-line anti-tuberculosis drugs. However, most antibacterial drugs are known to induce hepatotoxicity which may limit their adherence and hence lead to the developmen…
Olbrich L, Verghese VP, Franckling-Smith Z, Sabi I, Ntinginya NE, et al.
Background Childhood tuberculosis remains a major cause of morbidity and mortality in part due to missed diagnosis. Diagnostic methods with enhanced sensitivity using easy-to-obtain specimens are needed. We aimed to assess the diagnostic accuracy of the Cepheid Mycobacterium tube…
Oshima K, Nakajima C, Hirata K, Hayashi H, Kodama EN, et al.
Tuberculosis remains a major public health concern. Millions of tuberculosis cases and associated deaths have been reported worldwide. The Indo-Oceanic lineage Mycobacterium tuberculosis is common in Southeast Asia and causes extrapulmonary lesions. Only a few case studies on thi…
Md Mayin Uddin Hasan, Mohammad Injamul Hoq, Saifur R Chowdhury
**BACKGROUND:** Tuberculosis remains one of the primary infectious diseases in Bangladesh that affects both adults and children. Poor diagnostic criteria and insufficient reporting, especially of pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) in children, lim…
Amare W Tadesse, Noriah Maraba, Jason Alacapa, Katya Gamazina, Tanyaradzwa Dube, et al.
**BACKGROUND:** Tuberculosis remains a leading cause of death globally, particularly in countries with high tuberculosis and HIV burdens. Disruptions caused by the COVID-19 pandemic may have further impacted tuberculosis outcomes. This study examines on-treatment mortality and as…
Jiajia Yu, Yunqing Chang, Chen Liang, Shengsheng Liu, Liang Li, et al.
Extrapulmonary tuberculosis (EPTB) is a significant health problem which can lead to severe morbidity and mortality. In clinical practice, EPTB can have a variety of nonspecific clinical manifestations and can be concurrent with other types of EPTB. As information pertaining to c…
Abhishek S, Saikia UN, Gupta A, Bansal R, Gupta V, et al.
Background: Intraocular tuberculosis (IOTB), an extrapulmonary manifestation of tuberculosis of the eye, has unique and varied clinical presentations with poorly understood pathogenesis. As it is a significant cause of inflammation and visual morbidity, particularly in TB endemic…
van Leeuwen LM, Versteegen P, Zaharie SD, van Elsland SL, Jordaan A, et al.
…itis (TBM), the most severe extrapulmonary manifestation of tuberculosis, is caused by the pathogen Mycobacterium tuberculosis The M. tuberculosis complex includes seven lineages, all described to harbor a unique geographical dissemination pattern and clinical presentation. In th…
Aishwarya Alavandar
…CKGROUND:** Standard weight-based dosing of first-line anti-tuberculosis drugs does not consistently achieve therapeutic plasma concentrations in all patients. Inadequate drug exposure may contribute to poor treatment response, particularly in extrapulmonary and disseminated tube…
Alavandar A
Background Standard weight-based dosing of first-line anti-tuberculosis drugs does not consistently achieve therapeutic plasma concentrations in all patients. Inadequate drug exposure may contribute to poor treatment response, particularly in extrapulmonary and disseminated tuber…
Alehegn E, Gebreyohanns A, Berhane B, Wright J, Fantahun M, et al.
Background Extra pulmonary tuberculosis (EPTB) accounts for a significant proportion of tuberculosis (TB), a devastating disease of public health concern. The complexity of the cases, the involvement of many organs, resource constraints, and concerns regarding drug resistance mak…
Saha S
…ehend the diagnostic challenges of primary gastrointestinal tuberculosis (an uncommon extrapulmonary tuberculosis condition) utilizing the recently published case report of a young male with prolonged gastrointestinal symptoms and weight loss who received intermittent anti-tuberc…
Tebeje WT, Ayen AA, Argaw DA, Mulu TS, Abdulahi AA, et al.
Introduction and importance Tuberculosis (TB), a common chronic infectious disease, affected approximately 10.6 million people worldwide in 2021. While TB can affect the lungs (pulmonary TB) or other parts of the body, extrapulmonary TB, genital TB is a rare form of extrapulmonar…
Chaudhary R, Bhatta S, Singh A, Pradhan M, Srivastava B, et al.
Tuberculosis is an infectious disease caused by the Mycobacterium tuberculosis . It is a global health problem and major cause of death in resource-limited countries like Nepal. Timely diagnosis with sensitive testing methods could assist in early management of the disease. This …