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Li H, Gao M, Dong X, Zhang L, Yuan Y, et al.
…ective This study aimed to investigate the risk factors and pregnancy outcomes associated with recurrent tuberculosis (TB) during pregnancy among patients with a history of TB who underwent in vitro fertilization and embryo transfer (IVF-ET). Methods A retrospective case-control …
Dennis EM, Hao Y, Tamambang M, Roshan TN, Gatlin KJ, et al.
…es. The objective of this study is to explore the risks for pregnancy complications and in-hospital death among mothers diagnosed with TB across racial/ethnic groups in the US. Methods This retrospective cohort study utilized National Inpatient Sample data for all inpatient hospi…
Salazar-Austin N, Cohn S, Lala S, Waja Z, Dooley KE, et al.
Background Both pregnancy and human immunodeficiency virus (HIV) increase the risk of tuberculosis disease, which results in poor maternal, pregnancy, and infant outcomes. Isoniazid preventive therapy (IPT) reduces mortality among individuals living with HIV in high-burden settin…
Walles J, Winqvist N, Hansson SR, Sturegård E, Baqir H, et al.
…ckground Tuberculosis (TB) disease has been associated with pregnancy complications. However, the potential impact of TB infection (TBI) on pregnancy outcome is unknown. To investigate this, we conducted a register-based study in immigrant women screened with QuantiFERON assays f…
Tesfaye F, Sturegård E, Walles J, Bekele B, Bobosha K, et al.
…ntrol of tuberculosis (TB) infection could be influenced by pregnancy. To elucidate this, we longitudinally characterized Mycobacterium tuberculosis (Mtb)-specific and nonspecific immune responses in women during pregnancy and postpartum. HIV-uninfected women without past or curr…
LaCourse SM, Wagner AD, Cranmer LM, Copeland A, Maleche-Obimbo E, et al.
…gnant women. Recent trial results suggest increased adverse pregnancy outcomes associated with IPT during pregnancy. Data are limited regarding programmatic IPT use in pregnant PLHIV. Methods We assessed previous programmatic IPT during pregnancy among HIV-infected mothers on enr…
Theron G, Montepiedra G, Aaron L, McCarthy K, Chakhtoura N, et al.
…iving with human immunodeficiency virus (HIV) either during pregnancy or after delivery, showed that IPT during pregnancy increased the risk of composite adverse pregnancy outcomes, but not individual outcomes. Many known factors are associated with adverse pregnancy outcomes: th…
Amaeze OU, Isoherranen N
Pregnancy can increase the risk of latent tuberculosis infection (LTBI) progression to tuberculosis (TB) disease. Isoniazid (INH) is the preferred preventative treatment for LTBI in pregnancy. INH is mainly cleared by N-acetyltransferase 2 (NAT2) but the pharmacokinetics (PK) of …
Mokhele I, Jinga N, Berhanu R, Dlamini T, Long L, et al.
…cribed the safety of second-line anti-TB medications during pregnancy. We aim to describe TB treatment and pregnancy outcomes among pregnant women receiving second-line anti-tuberculosis treatment for MDR/RR-TB in Johannesburg, South Africa. Methods We conducted a retrospective r…
O'Kelly B, Murtagh R, Lambert JS
…nd the dominant drug class for the management of HIV during pregnancy for the previous decade. As with many drugs used during pregnancy, pharmacokinetic changes decrease exposure to these agents as the pregnancy progresses. This can lead to viral escape at the time of pregnancy a…
Quincer EM, Gobezayehu AG, Belew ML, Endalamaw LA, Tesfaye YA, et al.
Background Tuberculosis (TB) disease during pregnancy results in adverse maternal and infant outcomes. The development of a TB vaccine with potential for administration during pregnancy or lactation is a priority identified by the World Health Organization. We assessed the accept…
Meehan SA, Hesseling AC, von Delft A, Marx FM, Hughes JA, et al.
…rtality. Pregnant women with TB are at high risk of adverse pregnancy outcomes. This study aimed to determine risk factors for an adverse pregnancy outcome among pregnant women diagnosed with TB. Methods Using TB programmatic data, this retrospective cohort analysis included all …
Schröder C, Calite E, Böckenhoff P, Büttner T, Stein J, et al.
Aim Less than a dozen cases of psoas abscesses in pregnancy have been described in the literature. We reviewed the literature when treating a patient with a psoas abscess after ipsilateral double J-ureteral stent placement (in the following: "double J-stent") due to infected hydr…
Jiayu Wen, Jian-Qing He
…acteristics and outcomes of active tuberculosis (TB) during pregnancy after in vitro fertilization-embryo transfer (IVF-ET) with those in natural pregnancies. The aim was to assess the impact of the mode of pregnancy on TB and to gain a deeper understanding of the clinical c…
Shafi J, Virk MK, Kalk E, Carlucci JG, Chepkemoi A, et al.
…ter a medication has been licensed, plays a crucial role in pregnancy, as clinical trials often exclude pregnant people. It is important to understand how pregnancy PV projects operate in low- and middle-income countries (LMICs), where there is a disproportionate lack of PV data …
Moro RN, Scott NA, Vernon A, Tepper NK, Goldberg SV, et al.
…ine (P, 900 mg) (3HP) for latent infection treatment during pregnancy. Objectives To assess safety and pregnancy outcomes among pregnant women who were inadvertently exposed to study medications in two latent tuberculosis infection trials (PREVENT TB or iAdhere) evaluating 3HP an…
Gupta A, Hughes MD, Cruz JL, Avihingsanon A, Mwelase N, et al.
…ulosis prevention yet data on the safety of first-trimester pregnancy exposure are limited. Methods Planned secondary analysis in a TB prevention trial of adverse pregnancy outcomes among participants assigned to 9-month IPT who became pregnant during (IPT-exposed) or after (unex…
Gai X, Chi H, Cao W, Zeng L, Chen L, et al.
Background While miliary tuberculosis (TB) in pregnancy is rare after in vitro fertilization and embryo transfer (IVF-ET), it poses a serious threat to the health of pregnant women and their fetuses. The present study aimed to describe the clinical features of miliary TB and preg…
Wang K, Ren D, Qiu Z, Li W
Background Pregnancy complicated with tuberculosis is increasingly common. The clinical characteristics of pregnancy complicated with miliary tuberculosis are summarized in this study. Methods A retrospective analysis of pregnant patients with miliary tuberculosis was performed i…
Priya Kumari, Atima Bharti, Rani Hansda, Madhu
**INTRODUCTION:** Ectopic pregnancy (EP) is an obstetrical emergency. It could be considered a public health indicator in the developing world because ectopic pregnancy presents as an acute emergency and it is a life-threatening event, providing a picture of a health system's cap…
Saha A, Escudero JN, Layouni T, Mecha J, Maleche-Obimbo E, et al.
Background Pregnancy increases Mycobacterium tuberculosis (Mtb) reactivation risk and alters immune responses. We assessed Mtb-specific CD4+ T-cell responses in pregnant women with HIV (WLHIV) and without, including those receiving isoniazid preventive therapy (IPT). Methods We m…
Cherkos AS, LaCourse SM, Enquobahrie DA, Richardson BA, Bradford S, et al.
…ground Isoniazid preventive therapy (IPT) initiation during pregnancy was associated with increased incidence of adverse pregnancy outcomes in the TB APPRISE trial. Effects of in utero IPT exposure on infant growth are unknown. Methods This post-hoc analysis used data from the TB…
Starshinova A, Churilov LP, Kudryavtsev I, Rubinstein A, Belyaeva E, et al.
The combination of tuberculosis and pregnancy always raises questions about therapy, the specialness of management of pregnancy, obstetrics, postpartum period, and lactation; the effect of therapy on fetal development and the peculiarities of the tuberculosis course. Until recent…
Aloufi D, Baradwan S, AlTurkistany S, Hakeem G
BACKGROUND The incidence of tumors during pregnancy, generally, is very uncommon. The incidence of lung cancer during pregnancy, specifically, is exceedingly rare. Several investigations have documented favorable maternal-fetal outcomes for later pregnancies after pneumonectomy d…
Flores-Lovon K, Soriano-Moreno DR, Medina-Ramirez SA, Fernandez-Guzman D, Caira-Chuquineyra B, et al.
…ves To evaluate the efficacy of antituberculosis therapy on pregnancy outcomes in infertile women with genital tuberculosis. Design Systematic review. Data sources We searched in PubMed/MEDLINE, CENTRAL and EMBASE up to 15 January 2023. Additionally, we manually search the refere…