Showing 1–25 of 161 documents
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Kanjanaphan T
…igation of LTBI in healthcare personnel (HCPS) working with pediatric patients with active pulmonary TB and report the side effects of 12-week-isoniazid and rifapentine (3HP). Methods This contact investigation reviewed HCPS who were in close contact with pediatric pulmonary TB. …
Martinelli M, Giugliano FP, Strisciuglio C, Urbonas V, Serban DE, et al.
…accine-preventable diseases and opportunistic infections in pediatric inflammatory bowel disease (IBD) are increasingly recognized issues. The aims of this study were to evaluate vaccinations, immunization status, and consequent therapeutic management in children with IBD and to …
Kim Y, Bae KS, Choi UY, Han SB, Kim JH
Background The treatment of pediatric patients with latent tuberculosis infection (LTBI) is a crucial TB control strategy. LTBI is not a reportable communicable disease, and data regarding LTBI treatment in pediatric patients in Korea are scarce. This study aimed to investigate t…
Money NM, Schroeder AR, Quinonez RA, Ho T, Marin JR, et al.
Importance Medical overuse is common in pediatrics and may lead to unnecessary care, resource use, and patient harm. Timely scrutiny of established and emerging practices can identify areas of overuse and empower clinicians to reconsider the balance of harms and benefits of the m…
Peck GM, Staat MA, Huang FS, Khalil N, Boyce C, et al.
…ad of tuberculosis and the progression to active disease in pediatric patients. As of 2017, the short course combination regimen of weekly isoniazid and rifapentine (3HP) administered by directly observed therapy (DOT) has replaced 9 months of isoniazid as the standard of treatme…
Adusumelli Y, Tabatneck M, Sherman S, Lamb G, Sabharwal V, et al.
… to engaging in TB infection care is critical to preventing pediatric TB disease. We explored families' and clinicians' perspectives on pediatric TB infection diagnosis and care. Methods We conducted individual interviews and small group discussions with primary care and subspeci…
Surve S, Naukariya K, Shah I
…s been reported between 21 and 48%. The exact prevalence of pediatric LTBI in India is still not clear, however, as per few studies, the LTBI prevalence ranges around 40% and 22% in adolescent followed by under-5 population. Studies to fill in the research gap of scarcity of prev…
Campbell J, Sandora T, Haberer J
…ts to eliminate TB by 2030. Identification and treatment of pediatric LTBI requires completion of a complex care cascade. While attention has been given to LTBI care cascades in adults, to date there has been no attempt to map literature on the pediatric LTBI care cascade. Facili…
Jeanine Diur Yav, Armand Mutwadi, Albert Kalonji, Fiston Ilunga Mbayo, Pacifique Kanku Wa Ilunga, et al.
… vulnerable group. In the Democratic Republic of the Congo, pediatric TB continues to be underdiagnosed and underreported, particularly in rural health zones such as Kabondo Dianda. **OBJECTIVE:** This study aimed to assess the knowledge, perceptions, and practices of guardians …
Gaensbauer J, Aiona K, Haas M, Reves R, Young J, et al.
…BI) to active disease. Therefore, regimens for treatment of pediatric LTBI must be not only efficacious but practical enough to overcome the unique childhood barriers to regimen adherence. Since 2012, a 4-month regimen of daily rifampin (4R) has been the standard recommendation f…
Ma HW, Lee HS, Ahn JY
…e target for reducing the infection rate. The management of pediatric LTBI is especially crucial because children can serve as a long-term source of infection upon developing active tuberculosis. Therefore, it is important to assess pediatric LTBI using contact investigation and …
Mase A, Ryan S, Mader G, Alvarez A, Armitige L, et al.
…ement of TB in children has not been described. We analyzed pediatric TB consultations performed across all RTMCCs in terms of question type, provider type, and setting. Methods The CDC medical consultation database was queried for consultations regarding patients ≤ 18 years prov…
Gaensbauer J, Broadhurst R
…ests and broader application in non-sputum samples for both pediatric pulmonary and extrapulmonary tuberculosis. Finally, recent studies have provided solid evidence in support of shorter treatment courses for pediatric latent tuberculosis infection, such as 12 weeks of weekly is…
Malhotra S, Dasgupta-Tsinikas S, Yumul J, Kaneta K, Lenz A, et al.
…aluate implementation of rifamycin-based regimens (RBR) for pediatric tuberculosis infection (TBI) treatment among 3 provider settings in a high-incidence county. Study design A multicenter, retrospective observational study was performed across 3 sites in Los Angeles County: an …
Hoekstra N, Anderson M, Gaensbauer J
…logy and risk factors informing current American Academy of Pediatrics (AAP) guidelines on screening for pediatric latent tuberculosis infection (LTBI) have evolved over the past decade. To improve pediatric LTBI screening efficiency, we sought to reevaluate characteristics assoc…
Bedir Demirdag T, Ozkaya Parlakay A, Aydin F, Tugcu GD, Santaflıoglu B, et al.
… who received different biologic modifying therapies in our pediatric rheumatology department and the possibility of development of tuberculosis (TB). Methodology This retrospective study was conducted in Ankara City Hospital. Pediatric patients who were treated with biologic mod…
Uet Yu, Jiaming Yu, Xindan Lian, Yu Liu, Xiaodong Wang, et al.
… these patients, data on TB prophylaxis and its outcomes in pediatric HSCT recipients remain limited. **METHODS:** We conducted a retrospective study of 714 pediatric HSCT recipients at Shenzhen Children’s Hospital from January 2018 to December 2021. Patients were categor…
Nadege Nziza, Wonyeong Jung, Tina Chen, Yixiang Deng, Kees L M C Franken, et al.
… to severe forms of the disease. However, whether different pediatric outcomes relate to distinct immunologic responses remains incompletely understood. Emerging data suggest that Mtb-specific humoral immune responses represent a correlate of protection against Mtb both following…
Nordholm AC, Holden IK, Hartling UB, Andersen PH, Lillbaek T, et al.
Background In Western Europe, most pediatric tuberculosis (TB) cases occur among immigrants; however, data are rarely stratified by first/second-generation immigrants and many cases may be preventable. Methods This was a nationwide study of children Results We identified 145 case…
Gaensbauer J, Gonzales B, Belknap R, Wilson ML, O'Connor ME
…uantiFERON-tuberculosis (TB) Gold (QFT)-based screening for pediatric latent TB infection (LTBI) in the Denver Health Community Health System (CHS), an urban primary-care network in the US. Study design We retrospectively analyzed all QFTs (n = 6685) performed on children aged 2-…
Nur Sunar Yayla E, Yıldız Ç, Esmeray Şenol P, Karaçayır N, Gezgin Yıldırım D, et al.
… of this study is to analyze the adverse events observed in pediatric patients who received biological treatment. Materials and methods This retrospective observational cohort study was conducted between January 2010 and January 2022. File records of 139 patients used biological …
Zhang S, Li X, Chen H, Gao X, Cai Z, et al.
…d become a new biomarker for the diagnosis and treatment of pediatric systemic lupus erythematosus (SLE) patients. Methods We have analyzed the clinical data of 776 children who are underwent TB-IGRA testing in the Department of Allergy and Rheumatology of Guangzhou Women and Chi…
Sayyahfar S, Mahdavi M, Seyedi Arani S, Fotovati Z
…his study aimed to compare TST and IGRA to diagnose LTBI in pediatric heart transplant candidates. Methods This cross-sectional study was performed on 50 children, who were candidates for heart transplantation, of whom 42 cases underwent heart transplantation in Shahid Rajaie Car…
Druszczynska M, Seweryn M, Wawrocki S, Pankowska A, Kulbachko A, et al.
… determine if IP-10 could be a useful diagnostic marker for pediatric tuberculosis, either alongside or as an alternative to IFN-γ. Results Both urine and QFT cultures stimulated with M.tb antigens showed significantly higher IP-10 levels in individuals with active TB or latent T…
Elif Kilic Konte, Nergis Akay, Umit Gul, Kubra Ucak, Ecenur Izzete Derelioglu, et al.
…riod by documenting adverse events in patients with various pediatric rheumatic diseases. **RESEARCH DESIGN AND METHODS:** This retrospective observational study was conducted at the Pediatric Rheumatology Department of Istanbul University Cerrahpasa between 2015 and 2023. The a…