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Neyro SE, Squassi IR, Medín M, Caratozzolo A, Martínez Burkett A, et al.
Extrapulmonary tuberculosis accounts for 15-20 % of all clinical presentations of tuberculosis. Peripheral tuberculous lymphadenitis is the second most common presentation of extrapulmonary tuberculosis in children, after pleural tuberculosis, in Argentina. We analyzed 92 patient…
Wang DM, Wang C, An Q, Yang Q, Liao Y
…ample, dynamic epidemiology, and characteristic analysis of pediatric tuberculosis (TB) in Southwest China is not clear. Herein, we conducted descriptive dynamic epidemiology, characteristic analysis and geographical distribution study of pediatric TB inpatients in Southwest Chin…
Awang H, Nik Husain NR, Abdullah H
Objectives We sought to determine the total proportion of pediatric tuberculosis cases, characterize tuberculosis by its anatomical location and pretreatment sputum smear status, and to determine the association of the sociodemographic and clinical factors with tuberculosis disea…
Pooja Semwal, Manjit Kaur Saini, Moinak Sen Sarma
…atotoxicity (ATDIH) is a significant concern while managing pediatric tuberculosis. There is limited data on pediatric ATDIH, and much of the management practices are extrapolated from adult experiences. This article provides a comprehensive overview of the incidence, risk factor…
…cal trends of the different clinical presentations of TB in pediatric population. Methods A retrospective, cross-sectional study, carried out at a pediatric referral hospital in Mexico between 2012-2021. Pediatric patients diagnosed with TB were included. Descriptive statistics w…
Mohammed Suleiman, Andrés Pérez-López, Ruwa Mohamed, Faheem Mirza, Amina Souli, et al.
…GX-MTB/R) assay, with conventional mycobacterial culture in pediatric non-sputum samples. A total of 417 non-sputum samples from a tertiary pediatric facility underwent simultaneous GX-MTB/R-U and culture testing. Performance was evaluated using conventional culture as a gold sta…
Gupta S, Vats P, Jha A, Singh K, Ghosh S, et al.
…l manifestations of tuberculosis (TB) in the oral cavity in pediatric patients. Study design Four pediatric patients were enrolled in the study. Clinical symptoms, auxiliary examinations, treatments, and outcomes were recorded and analyzed. Four pediatric patients who presented w…
Chu P, Chang Y, Zhang X, Han S, Jin Y, et al.
ABSTRACT Pediatric tuberculosis (TB) is a serious infectious disease that affects many children worldwide and is more likely to be extrapulmonary than adult TB. However, the clinical and epidemiological profile, and cost burden of pediatric extrapulmonary TB (EPTB) in China remai…
Gupta N, Kashyap B, Dewan P, Hyanki P, Singh NP
Aim and objectives The paucibacillary nature of pediatric tuberculosis (TB) makes diagnosis difficult. The aim of the study was to correlate the clinical spectrum of pediatric TB with microbiological diagnosis. Materials and methods Specimens from clinically suspected pediatric T…
Pace D, Pellegrino R, Dalpiaz I, Renni M, Galli L, et al.
Introduction The diagnosis of pediatric tuberculosis (TB) is challenging, due to the lower sensitivity of microbiological tests, such as culture and microscopy, compared to their performance in adult cases. Guidelines have introduced molecular tests, including GeneXpert MTB/ RIF …
Dilia Fontalvo-Rivera, Maria Daniels-García, Jesly Doria-Atencia, Karen Tous-Barrios, Liliana Molinares-Núñez, et al.
…y diagnostic methods for EPTB at the point of care (POC) in pediatric patients at a referral hospital. **PATIENTS AND METHOD:** Retrospective study in both male and female patients aged 0-17 years hospitalized from January 2012 to January 2022 in a pediatric referral hospital in…
Drobish I, Ramchandar N, Raabe V, Pong A, Bradley J, et al.
…losis (MTB) complex infections in children and 1%-2% of all pediatric tuberculosis infections. Treatment regimens and durations typically mirror recommendations for other types of extrapulmonary MTB, but there are significant variations in practice, with some experts suggesting a…
Babak Pourakbari, Hani Rostami Rad, Maryam Sotoudeh, Reihaneh Hosseinpour Sadeghi, Shima Mahmoudi, et al.
**BACKGROUND:** Pediatric tuberculosis (TB) remains a significant global health issue due to its diagnostic complexity and paucibacillary nature. This study aimed to evaluate the clinical, diagnostic, and immunological characteristics of pulmonary TB (PTB) and extrapulmonary TB (…
Hamdar H, Nahle AA, Ataya J, Jawad A, Salame H, et al.
…ristics, diagnostic methods, and early mortality rate among pediatric patients with pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) who were admitted to a hospital in Syria. Methods This retrospective cohort study was conducted at the University Children's Hos…
Paradkar MS, Devaleenal D B, Mvalo T, Arenivas A, Thakur KT, et al.
Background Pediatric tuberculous meningitis (TBM) commonly causes death or disability. In adults, high-dose rifampicin may reduce mortality. The role of fluoroquinolones remains unclear. There have been no antimicrobial treatment trials for pediatric TBM. Methods TBM-KIDS was a p…
Maloney ME, Cohen B
…ence increasing in the United States from 2020 to 2021. The pediatric population is particularly vulnerable to TB. Extrapulmonary manifestations of TB include cutaneous tuberculosis (CTB). Observations There are 8 forms of CTB. Lupus vulgaris (LV) is the second most common form o…
Jian Zeng, Haitao Su, Jin Wang, Jiaohong Zhang, Shuihua Lu, et al.
…nvestigate the clinical features and prognostic outcomes of pediatric tuberculosis (TB) in Shenzhen. **METHODS:** This retrospective study collected demographic, clinical, laboratory, and prognostic data from pediatric patients diagnosed with TB between January 2013 and January …
Drobish I, Ramchandar N, Raabe V, Pong A, Bradley J, et al.
…ted for MTB complex OAI over a 26-year period at a tertiary pediatric center in southern California. Methods We conducted a retrospective review of children diagnosed with MTB complex OAI and cared for between 31 Dec 1992 to 31 Dec 2018 at a single tertiary care pediatric hospita…
Ayimen Khalid Khan, Shayan Sirat Maheen Anwar, Ashok Kumar, Anam Khan
…ntries, including Pakistan, where it is highly endemic. The pediatric population is particularly at high risk of developing CNS tuberculosis. This disease can manifest in various forms, such as tuberculous meningitis, tuberculoma, tubercular abscess, Pott's spine, and tuberculous…
González Saldaña N, Macías Parra M, Xochihua Díaz L, Palavicini Rueda M, Carmona Vargas AJ, et al.
…steoarticular tuberculosis (OATB) in patients in a tertiary pediatric hospital, to know if the diagnosis of OATB in pediatrics is a challenge due to its insidious clinical presentation. Methods A retrospective, descriptive study of the cases of Tuberculosis (TB) in children was c…
He Y, Lyon CJ, Nguyen DT, Liu C, Sha W, et al.
Diagnosis of pediatric tuberculosis (TB) is often complicated by its nonspecific symptoms, paucibacillary nature, and the need for invasive specimen collection techniques. However, a recently reported assay that detects Mycobacterium tuberculosis virulence factors in serum can di…
Grønningen E, Nanyaro M, Sviland L, Ngadaya E, Muller W, et al.
Pediatric extrapulmonary tuberculosis (EPTB) is a diagnostic challenge. A new immunochemistry based MPT64 antigen detection test has shown improved sensitivity compared to current laboratory tests. The aim of this study was to implement and validate the test performance in a reso…
Hamdar H, Nahle AA, Ataya J, Jawad A, Salame H, et al.
…ristics, diagnostic methods, and early mortality rate among pediatric patients with pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) who were admitted to a hospital in Syria. This retrospective cohort study was conducted at the University Children's Hospital in…
Hendriarto A, Juliandri R, Hartanto BR
…zation, and surgery. The use of Gardner well tongs (GWT) in pediatrics spinal TB is rare due to associated risks and lack of supporting evidence. This case report aims to document the application of GWT traction in conjunction with surgical intervention for a pediatric patient wi…
Grohs E, Short M, Griffin G, Sheets A, Tegarden T, et al.
… in facilities with robust TB control programs. We report a pediatric case of TB meningitis who had an adult visitor with active pulmonary TB. We identified 96 contacts from the index case. One high-risk contact had a positive follow-up TB test with no clinical symptoms. TB contr…