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Baggaley RF, Vegvari C, Dimala CA, Lipman M, Miller RF, et al.
…ences. Databases were searched 1980-2020. Studies including health economic evaluation of LTBI screening of PLWH in lower TB incidence countries ( Results: Of 2,644 articles screened, nine studies were included. Cost-effectiveness estimates of LTBI screening/PT for PLWH varied wi…
Menzies NA, Shrestha S, Parriott A, Marks SM, Hill AN, et al.
…o progress to tuberculosis (TB). We estimated the potential health and economic benefits of diagnostics with improved discrimination for LTBI that will progress to TB. Methods A base case scenario represented current LTBI testing and treatment services in the United States in 202…
Pareek M, Eborall HC, Wobi F, Ellis KS, Kontopantelis E, et al.
…alitative sub-study to understand the views of migrants and healthcare professionals to the new testing policy in primary care. Finally, we will evaluate the cost-effectiveness of combined infection testing for migrants in primary care. Ethics and dissemination The study has rece…
Wong YJ, Ng KY, Lee SWH
…p-outs from the LTBI cascade of care are minimized. Digital health technology could play an important role in case detection and treatment adherence. This study aims to evaluate the use and impact of digital health technology in LTBI care. Methods A systematic literature search w…
Espinoza E, Shaughnessy M, Walker P, Husmann R, Hale G, et al.
… due to language, cultural, and economic issues. Unprepared health systems and providers further contribute to health disparities in transplantation. Foreign-born patients are also at risk for reactivation of latent infections which differ from U.S.-born population. Stratifying t…
Shedrawy J, Deogan C, Öhd JN, Hergens MP, Bruchfeld J, et al.
Introduction The majority of tuberculosis (TB) cases in Sweden occur among migrants from endemic countries through activation of latent tuberculosis infection (LTBI). Sweden has LTBI-screening policies for migrants that have not been previously evaluated. This study aimed to asse…
Appa A, Miller AP, Fatch R, Kekibiina A, Beesiga B, et al.
Economic incentives to promote health behavior change are highly efficacious for substance use disorders as well as increased medication adherence. Knowledge about participants' experiences with and perceptions of incentives is needed to understand their mechanisms of action and …
Ping PA, Zakaria R, Islam MA, Yaacob LH, Muhamad R, et al.
…impose a high disease burden in terms of both mortality and health economics worldwide. The objective of this study was to estimate the prevalence and risk factors of latent TB infection (LTBI) in patients with T2DM in Malaysia. A cross-sectional study was performed, and adult T2…
Rizzi A, Nucera E, Mazzucco W, Palumbo P, Staiti D, et al.
…on or reactivation of latent disease, the screening of both health-care workers (HCWs) and students is an important issue in the TB control program. Objective to deploy a web-based platform interoperating health surveillance systems from different hospitals to define models based…
Hualin Jiang, Rui Li, Tianhua Zhang, Qinghu Wang, Haini Liu, et al.
…d impact on reducing TB incidence. We aimed to evaluate the health impact and cost-effectiveness of expanding TPT to key community-level population METHODS: We developed a dynamic transmission model incorporating the effect of TPT and seasonal variations in TB incidence. The mode…
To KW, Zhang R, Lee SS
… studies for TBST have been conducted without exploring the health economics for preventing development of LTBI into active TB. Unlike IGRA, no clinical studies have addressed the correlation of TBST results (magnitude of induration) with the likelihood of development of active T…
Halliday A, Jain P, Hoang L, Parker R, Tolosa-Wright M, et al.
…ures, measured each of the new technologies and performed a health economic analysis in which the best-performing tests were evaluated for cost-effectiveness. The diagnostic accuracy of the transcriptomic tests ranged from an AUC of 0.81 to 0.84 for detecting all TB in our cohort…
Navarro CE, Benjumea-Bedoya D, Estupinan-Bohorquez AF, Florez ID
… tuberculosis (TB) patients in the context of the Colombian healthcare system. Design Health economic evaluation. Decision tree over a horizon of Setting From the perspective of the Colombian healthcare system, the direct healthcare costs related to tests were considered, and dia…
Mathilda Regan, Hening Cui, Nicole A Swartwood, Yunfei Li, Suzanne M Marks, et al.
…nicity. A Markov cohort model was used to simulate lifetime health and economic outcomes under the intervention and status quo scenarios using 2011-19 tuberculosis surveillance data and published literature. **FINDINGS:** We designated 157 counties as intervention counties. The …
Kumari R S, Sethi G, Krishna R
…he host. Since 2020, the COVID-19 pandemic has had colossal health, societal, and economic consequences, which have affected the reporting of new incidences and mortality cases of TB. As per the WHO 2022 report, 10.6 million people were diagnosed with TB, and 1.6 million died wor…
Teixeira de Siqueira-Filha N, Militao de Albuquerque MF, Cunha Rodrigues L, Legood R, Costa Santos A
…rediagnosis and treatment periods from the Brazilian public health system perspective. We applied a combination of bottom-up and top-down approaches to capture and estimate direct medical and non-medical costs. We measured the mean cost per patient per type of care (inpatient, ou…
Pasticci MB, Papalini C, Murgia N, Papili R, Bucaneve G, et al.
…ies with a high incidence of TB and the rising attention of health care institutions to economic costs. The aim of this study was to compare QuantiFERON-TB (QFT) and TST results in active TB. We evaluated QFT results and TST reactions from 245 consecutive patients having both tes…
Ran F, Wang Y, Zhang G, Guo H, Li J, et al.
…bally, exhibiting high morbidity rates and impacting public health and other socio-economic factors. However, some individuals are resistant to TB infection and are referred to as "Resisters". Resisters remain uninfected even after exposure to high load of Mycobacterium tuberculo…
Malaisamy Muniyandi, Karikalan Nagarajan, Kavi Mathiyazhagan, Kirti Tyagi, Kavitha Rajsekar, et al.
…METHODS:** An economic modelling study was conducted from a health system perspective using decision tree analysis, which is most widely used for cost-effectiveness analysis using transition probabilities. Our goal was to estimate the incremental cost and number of TB cases preve…
Abdullahi LH, Oketch S, Komen H, Mbithi I, Millington K, et al.
Background Tuberculosis (TB) remains a public health concern in Kenya despite the massive global efforts towards ending TB. The impediments to TB prevention and care efforts include poor health systems, resource limitations and other sociopolitical contexts that inform policy and…
Jansen-Aaldring N, van de Berg S, van de Berg S, van den Hof S
…ision options and treatment adherence interventions such as health education, psycho-emotional and socio-economic support. Patient support for persons on treatment for latent tuberculosis infection was less widely (9/19) implemented. Patient support guidelines were available in 1…
Harries AD, Lin Y, Kumar AMV, Satyanarayana S, Takarinda KC, et al.
…pment, developing and implementing new tools, and expanding health insurance coverage. Within this broad framework, National TB Programmes (NTPs) are accountable for delivering diagnostic, treatment, and preventive services. There are large gaps in the delivery of these services,…
Auguste PE, Mistry H, McCarthy ND, Sutcliffe PA, Clarke AE
…istic and one-way sensitivity analyses. Setting UK National Health Service and Personal Social Service perspective in a primary care setting. Participants Hypothetical cohort of adults recently diagnosed with HIV. Interventions Interferon-gamma release assays and tuberculin skin …
De Matteis G, Scatà MC, Zampieri M, Grandoni F, Elnaggar MM, et al.
…n buffalo farming, and it poses a potential threat to human health. Interferon-gamma (IFN-γ) plays a central role in protection against mycobacterial diseases, illustrating the importance of T-cell mediated immune responses in tuberculosis infection. Recently, the expression of C…
Loureiro RB, Maciel ELN, Caetano R, Peres RL, Fregona G, et al.
…as to perform a cost-effectiveness analysis from the public health system perspective, comparing five strategies for Latent Tuberculosis Infection (LTBI) diagnosis in primary health care workers in Brazil. Design Analytical model for decision making, characterized by cost-effecti…