Showing 1–21 of 21 documents
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Juliet G Nyamasve, Nyaradzai A Katena, Shepherd Shamu, Junior Mutsvangwa, Aliasgar Esmail
…diagnosis is critical for reducing morbidity, mortality and health system costs, economic evaluations of EPTB diagnostics remain sparse and fragmented. This protocol aims to map existing evidence on the economic evaluation of diagnostic innovations for EPTB in low-resource settin…
Al-Zanbagi AB, Shariff MK
…rld too. Its worldwide prevalence with a huge impact on the healthcare system both in economic and health terms has prompted the World Health Organization to make it a top priority infectious disease. Tuberculous infection of the pulmonary system is the most common form of this d…
Subramonian A, Severn M
….2 million deaths attributable to the disease. The enormous health and economic burden caused by the disease make it a major public health issue. In Canada, active TB infection rates are one of the lowest in the world. There were 1,796 active cases of TB nationwide in 2017, mostl…
Julie Huynh, Chishala Chabala, Suvasini Sharma, Louise Choo, Varinder Singh, et al.
…c biomarkers, in-depth neurodevelopmental outcomes, MRI and health economics. **ETHICS AND DISSEMINATION:** Local ethics committees at all participating study sites and respective regulators approved the SURE protocol. Ethics approval was also obtained from UCL, UK (14935/001). …
Gopalaswamy R, Subbian S, Shanmugam S, Mondal R, Padmapriyadarsini C
Diseases due to pathogenic mycobacteria cause significant health and economic impact on humans worldwide. Although mycobacterial diseases primarily affect the lungs, the involvement of extrapulmonary organs has also gained ground, particularly among individuals with co-existing m…
Aldriwesh MG, Alaqeel RA, Mashraqi AM, Mashraqi MM, Albdah BA, et al.
…sis (anti-TB) treatment and how that might affect patients' health status. Here, the prevalence and etiologies of other LRTIs in a cohort of PTB patients were determined, and the clinical features and outcomes were described. Methods Adult patients with PTB between 2015 and 2020 …
van Elsland SL, van Dongen SI, Bosmans JE, Schaaf HS, van Toorn R, et al.
…n from a societal perspective using probabilistic analysis. Health care, informal care, lost productivity costs and costs in other sectors, health-related quality of life (HRQoL) and family impact were assessed during interviews with care givers, children, medical staff and manag…
Praveen Nayak, Vishnukanth Govindaraj, Dharm Prakash Dwivedi, Noyal M Joseph, T P Elamurugan, et al.
…BACKGROUND:** Tuberculosis (TB) continues to be the biggest health problem in developing countries with enormous social and economic implications. The commonest form of extrapulmonary TB (EPTB) is tubercular cervical lymphadenitis, or scrofula. The diagnosis and management of TB …
Shoaib Hassan, Mala Kanthali, Manju Raj Purohit, Tehmina Mustafa
…itis and 80% of pleuritis patients experienced catastrophic health expenditures (CHE), defined as costs exceeding 20% of annual income. Up to 42% of patients were pushed below the poverty line. Asset-based inequality analysis showed that lower socioeconomic groups faced a disprop…
Hassan S, Mustafa T, Muller W, Torres L, Marijani M, et al.
…onary Tuberculosis (EPTB) poses challenges from patient and health system perspectives. The cost-effectiveness analysis of the Xpert MTB/RIF (Xpert) test to diagnose pulmonary tuberculosis is documented. However, there are no economic evaluations for EPTB. Considering the reporte…
Febi AR, Manu MK, Mohapatra AK, Praharaj SK, Guddattu V
…valuated. We examined the level of psychological stress and health-related quality of life (HRQoL) of such patients and the effect of antituberculosis therapy on them. Our prospective cohort study included newly diagnosed adult pulmonary and extrapulmonary TB patients. Assessment…
Jørstad MD, Aẞmus J, Marijani M, Sviland L, Mustafa T
…erculosis (EPTB). The aims of this study were to assess the health care seeking behaviour, EPTB knowledge and diagnostic delay in presumptive EPTB patients at the main referral hospital in Zanzibar, factors associated with longer delay, and the impact of untreated EPTB on self-ra…
Chatterjee S, Toshniwal MN, Bhide P, Sachdeva KS, Rao R, et al.
…India. This study estimates the costs of TB services from a health systems´ perspective to facilitate the efficient allocation of resources by India´s National Tuberculosis Elimination Programme. METHODS: Data were collected from a multi-stage, stratified random sample of 20 faci…
Benjamin Hegarty, Paula Jops, Janet Gare, Jane Greig, Herick Aeno, et al.
… consistent calls to incorporate gender frameworks into One Health research and policy. Men's and women's roles in relation to animals in many rural and agricultural communities may influence potential pathogen exposure and transmission patterns of zoonotic infectious diseases. H…
Ravikumar DB, Sivasubramanian BP, Singla A, Venu R, Shekar SP
…resulting in the alleviation of symptoms and better overall health outcomes.
Baloyi DP, Myburgh H, Bester D, Anthony MG, Switala J, et al.
…stand how patients are evaluated. This study aimed to chart health systems for paediatric TBM care at both primary healthcare (PHC) and hospital level in Cape Town, South Africa. We conducted fourteen in-depth interviews and eight days of semi-structured observations of patient f…
Meregildo-Rodriguez ED, Asmat-Rubio MG, Vásquez-Tirado GA
Tuberculosis is a rising global public health emergency. Then, it is a priority to undertake innovations in preventive, diagnostic, and therapeutic methods. Improved diagnostic methods for tuberculosis are urgently needed to address this global epidemic. These methods should be r…
Alexander J Stockdale, Benno Kreuels, Isaac T Shawa, Niza M Silungwe, Blessings Mbale, et al.
**BACKGROUND:** African countries have the highest age-standardised mortality from liver disease. We studied patients with cirrhosis and hepatocellular carcinoma in Malawi to ascertain the causes, associated exposures, and outcomes after discharge, and identify opportunities for …
Jackline Anase Nlula, Sembakutti Samita, Etienne Yuh Jam, Bernard Ngowi, Ellen Mitchell, et al.
…targeted interventions, including strengthened occupational health policies, enhanced community-based screening, and focused strategies for high-risk groups is essential to improving TB control in Tanzania.
Sailo CV, Tonsing MV, Sanga Z, Chhakchhuak Z, Kharkongor F, et al.
…ished risk factors. Methods A total of 400 TB cases and 840 healthy controls were interviewed from December 2017 - June 2020. Logistic regression model was used to analyze associated risk factors. Patients were categorized into pulmonary and extrapulmonary TB. Results Clinical pr…
Teunissen CE, Rohlwink U, Pajkrt D, Naudé PJW
…urdens of disease in Africa and can negatively affect brain health. Two thirds of the world's population of people living with HIV reside in sub-Saharan Africa and 25% of the global burden of tuberculosis (TB) is carried by the African continent. Neuroinflammation and damage of s…