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Peiyu Xu, Shenni Liang, Andrew Hahn, Vivian Zhao, Wai Tung 'Jack' Lo, et al.
…forming public health strategies. However, existing genomic epidemiology simulators typically assume conditional independence among these processes: generating transmission trees independently of pathogen evolution, and then superimposing neutral mutations onto fixed genealogies …
Zongying Zhan, Tiancheng Xie, Tianshuo Zhao, Xiyu Zhang, Sihui Zhang, et al.
**OBJECTIVE:** To analyse temporal trends of respiratory infectious diseases (RIDs) in Baiyin City from 2014 to 2023, aiming to explore the epidemiological patterns of these diseases (tuberculosis, scarlet fever, pertussis, measles, influenza, mumps, varicella and rubella) and pr…
Carson J, Keeling M, Ribeca P, Didelot X
…nfluenza H7N7 in the Netherlands to reconstruct its spatial epidemiology. In both cases, we show that incorporating epidemiological data into the genomic analysis allows us to investigate the role of epidemiological properties in the spread of infectious diseases.
Jajou R, de Neeling A, van Hunen R, de Vries G, Schimmel H, et al.
Background Patients with Mycobacterium tuberculosis isolates sharing identical DNA fingerprint patterns can be epidemiologically linked. However, municipal health services in the Netherlands are able to confirm an epidemiological link in only around 23% of the patients with isola…
Goscé L, Tadesse AW, Foster N, van Kalmthout K, Rest JV, et al.
Background Digital adherence technologies (DATs) with associated differentiated care are potential tools to improve tuberculosis (TB) treatment outcomes and reduce associated costs for both patients and healthcare providers. However, the balance between epidemiological and econom…
Buenestado-Serrano S, Martínez-Lirola M, Dippenaar A, Sanz-Pérez A, Garrido-Cárdenas JA, et al.
The transition from MIRU-VNTR-based epidemiology studies in tuberculosis (TB) to genomic epidemiology has transformed how we track transmission. However, short-read sequencing is poor at analyzing repetitive regions such as the MIRU-VNTR loci. This causes a gap between the new ge…
Sadovska D, Ozere I, Pole I, Ķimsis J, Vaivode A, et al.
Background Tuberculosis remains a global health threat, and the World Health Organization reports a limited reduction in disease incidence rates, including both new and relapse cases. Therefore, studies targeting tuberculosis transmission chains and recurrent episodes are crucial…
Jiomekong A, Camara G
Epidemiological surveillance systems enable collection, analysis and dissemination of information on the monitored disease to different stakeholders. It may be done manually or using a software. Given the poor performances of manual systems, the software approach is generally ado…
Jajou R, Kohl TA, Walker T, Norman A, Cirillo DM, et al.
BackgroundWhole genome sequencing (WGS) is a reliable tool for studying tuberculosis (TB) transmission. WGS data are usually processed by custom-built analysis pipelines with little standardisation between them.AimTo compare the impact of variability of several WGS analysis pipel…
Zheng MQ, Li XX, Xu R, Liu S, Rui ZY, et al.
… literature study. In this study, publications on molecular epidemiology were analyzed using bibliometric analysis. The statistical analysis of influential publications, journals, countries and authors was first conducted. Methods The Web of Science database was searched for publ…
Nicola Harvey, Guy McGrath, James O'Shaughnessy, Jamie A Tratalos, Brian Byrne, et al.
… health, biosecurity and the economy. The complexity of bTB epidemiology, driven by multiple host species, undetected transmission and incomplete diagnostic sensitivity, makes surveillance and control challenging. Pathogen whole-genome sequencing (WGS) can clarify transmission dy…
Menean M, Scandale P, Apuzzo A, Barresi C, Checchin L, et al.
…-threatening inflammatory conditions. Understanding uveitis epidemiology, etiology, and clinical findings is fundamental for a prompt diagnosis and optimal patient management. The aim of the study is to report the epidemiology of uveitis in a national referral center in Northern …
Carlos Cifuentes-González, Germán Mejía-Salgado, William Rojas-Carabali, Josué Tovar-Tirado, Luis Alejandro Diez-Bahamón, et al.
… its clinical importance, the global incidence and detailed epidemiology of scleritis are poorly understood due to its heterogeneity and rarity. This systematic review and meta-analysis aim to elucidate the worldwide incidence and epidemiological trends of scleritis, examining va…
Rina de Zwaan, Gerard de Vries, Ella Ubbelohde, Arnout Mulder, Miranda Kamst-van Agterveld, et al.
Whole genome sequencing (WGS) is able to identify epidemiological links between Mycobacterium tuberculosis isolates. Recent clustering can be ruled out using a pre-defined single nucleotide polymorphism (SNP) threshold. If WGS clusters grow significantly over time limited genetic…
Cheng B, Behr MA, Howden BP, Cohen T, Lee RS
…cs have become increasingly important in infectious disease epidemiology and public health. The Strengthening the Reporting of Molecular Epidemiology for Infectious Diseases (STROME-ID) guidelines were developed to outline a minimum set of criteria that should be reported in geno…
Ni X, Zhu C, Li Q, Jiang H, Liu J, et al.
…where the tuberculosis incidence rate is high. However, the epidemiology characteristics of M. tuberculosis L4 in China remain poorly understood. Here, the 15-loci Variable number of tandem repeats (VNTR) patterns of 975 L4 isolates from a National Survey of Tuberculosis in China…
Rito T, Matos C, Carvalho C, Machado H, Rodrigues G, et al.
…episodes of transmission, mostly undetected using classical epidemiology alone. Conclusions Although control policies have been successful in decreasing incidence in Porto, the discerned complexity suggests that, for elimination to be a realistic goal, strategies need to be adjus…
Pelissari DM, Rocha MS, Bartholomay P, Sanchez MN, Duarte EC, et al.
Objectives To identify scenarios based on socioeconomic, epidemiological and operational healthcare factors associated with tuberculosis incidence in Brazil. Design Ecological study. Settings The study was based on new patients with tuberculosis and epidemiological/operational va…
Li Y, Hu Y, Mansjö M, Zhao Q, Jiang W, et al.
This study aimed to validate the epidemiological significance and temporal stability of Mycobacterial Interspersed Repetitive Units-Variable Number of Tandem Repeats (MIRU-VNTR) typing in a genetically and geographically diverse set of clinical isolates from patients diagnosed wi…
Aaby P, Benn CS
Background Epidemiological and immunological studies are increasingly reporting non-specific effects (NSEs) of vaccines; i.e. vaccines may affect the risk and severity of non-targeted infections. We reviewed how epidemiological studies developed the concept of beneficial NSEs of …
Reis AC, Albuquerque T, Botelho A, Cunha MV
…vine TB control. Furthermore, the information regarding the epidemiology and biology of M. caprae is quite limited comparing to the cognate bovine-adapted ecotype, M. bovis. In this work, we applied spoligotyping and MIRU-VNTR (Mycobacterial Interspersed Repetitive Units-Variable…
Yerezhepov D, Gabdulkayum A, Akhmetova A, Kozhamkulov U, Rakhimova S, et al.
…e rate of TB in Kazakhstan, our research aimed to study the epidemiology and genetics of PTB in Kazakhstan. Materials and methods 1,555 participants were recruited to the case-control study. The epidemiology data was taken during an interview. Polymorphisms of selected genes were…
Chen WY, Chen YF, Tsai JM, Huang HM, Su YC
…n binary and ternary mixtures on Daphnia magna and used the epidemiology of TB history to construct epidemiology-based wastewater monitoring for assessing the environmental release of residues and related ecological risks. The acute immobilization of median effect concentrations …
Jun Komukai, Kaori Yamamoto, Osamu Tokunaga, Hiharu Inoue, Takayuki Wada
…rom 2008-2023, focusing on diagnostic methods and molecular epidemiology using variable number of tandem repeats (VNTR) analysis and whole-genome sequencing (WGS). Among 29 children aged 0-14 years (notification rate: 0.04 per 100,000), three (10.3%) were born abroad, and five (1…
Bandopadhyay S, Gupta A, Banerjee A, Gupta P
… they have occurred many times in history. The discourse of epidemiology describes mainly the causal factors which need to be mitigated to prevent or combat the effects of epidemics. In epidemiology, we are not concerned for a person, but rather every individual globally, to make…