Showing 1–16 of 16 documents
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du Preez K, Osman M, Seddon JA, Naidoo P, Schaaf HS, et al.
Background Few studies have evaluated tuberculosis control in children and adolescents. We used routine tuberculosis surveillance data to quantify age- and human immunodeficiency virus (HIV)-stratified trends over time and investigate the relationship between tuberculosis, HIV, a…
Katherine C Horton, Alvaro Schwalb, Martin J Harker, Lara Goscé, Elena Venero-Garcia, et al.
… or evaluated between settings with different background TB epidemiology and structural drivers. **METHODS:** We calibrated a deterministic TB model to epidemiological indicators in Brazil, India, and South Africa. We implemented seven interventions across countries focusing on …
van den Boom M, Bennani K, Sismanidis C, Gunneberg C, Khawaja L, et al.
Background In Pakistan, 84% of healthcare is provided by the private sector. We conducted an epidemiological and programme review for TB to document progress and guide further efforts. Methods Surveillance and data systems were assessed before analysing epidemiological data. We r…
Y L Lew, M M D Goroh, S T Yerkovich, A M H Seow, G S Rajahram, et al.
…hose with drug-sensitive TB (DS-TB). Our study examined the epidemiology of DR-TB in Sabah, Malaysia, a state with high TB burden. We aimed to identify factors associated with poor treatment outcomes. **STUDY DESIGN:** Retrospective cohort study. **METHODS:** Data were derived …
Ruizhuang Sun, Yan Jiang, Yingyu Yan, Tingxia Zhou, Chonghui Xu, et al.
**BACKGROUND:** With the widespread implementation of antiretroviral therapy (ART), human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) has gradually transitioned from a highly fatal infectious disease to a manageable chronic condition. Simultaneously, glob…
Benito P, Vashakidze S, Gogishvili S, Nikolaishvili K, Despuig A, et al.
This study aimed to determine the health-related quality of life (HRQoL) of patients with pulmonary tuberculosis (TB) and to assess its change after a therapeutic surgical procedure. In this scenario, the purpose was to elucidate and quantify the effect of various demographic, ep…
Jeong D, Kim J, Lee SW, Choi H, Sohn H, et al.
… comprehensive, linked dataset for advancing research on TB epidemiology, treatment outcomes, comorbidities, and health disparities. It enables evaluations of public health interventions, long-term prognosis, and strategies for post-TB care. This cohort will remain a valuable res…
Radtke KK, Dooley KE, Dodd PJ, Garcia-Prats AJ, McKenna L, et al.
Background Malnourished and young children are particularly susceptible to severe forms of tuberculosis and poor treatment response. WHO dosing guidelines for drugs for tuberculosis treatment are based only on weight, which might lead to systematic underdosing and poor outcomes i…
Arinaminpathy N, Gomez GB, Sachdeva KS, Rao R, Parmar M, et al.
There is increasing interest in future, highly-potent 'pan-TB' regimens against tuberculosis (TB), that may be equally effective in both drug-susceptible and rifampicin-resistant (RR) forms of TB. Taking the example of India, the country with the world's largest burden of TB, we …
McDonald AK, Nakkonde D, Kaggwa P, Zalwango S, Joseph A, et al.
Background Growing evidence suggests that post-TB-related morbidity occurs often among TB survivors, but there is limited epidemiological data on the burden of symptoms and disability after successful completion of treatment. We evaluated the prevalence of TB-related symptoms, se…
Chidambaram V, Ruelas Castillo J, Kumar A, Wei J, Wang S, et al.
Tuberculosis (TB) and atherosclerotic cardiovascular disease (ASCVD) have a close epidemiological and pathogenetic overlap. Thus, it becomes essential to understand the relationship between ASCVD and TB outcomes. From our retrospective cohort on drug-susceptible TB patients at th…
Bea S, Lee H, Kim JH, Jang SH, Son H, et al.
Background: Adherence to tuberculosis (TB) drugs is one of the key aspects of global TB control, yet there is a lack of epidemiological evidence on the factors influencing adherence to TB drugs. Thus, this study aimed to explore the adherence and factors associated with adherence…
Dillon Prus, Robert Lenox
Moxifloxacin (MXF) is a cornerstone of the newly recommended four-month 2HPMZ/2HPM regimen for drug-susceptible pulmonary tuberculosis (TB). However, potential side effects such as cumulative neurotoxicity remain poorly characterized in clinical practice. Here, we report a rare c…
Seung Won Lee, Doosoo Jeon, Hongjo Choi, Chiwook Chung, Jeongha Mok, et al.
…s study investigated the effect of population ageing on the epidemiology of tuberculosis (TB) in South Korea. **METHODS:** We conducted a retrospective cohort study using an integrated database from three national databases. We analysed trends in age-specific TB incidence, morta…
Liu Y, Moodley M, Pasipanodya JG, Gumbo T
Antimicrobial susceptibility testing, based on clinical breakpoints that incorporate pharmacokinetics/pharmacodynamics (PK/PD) and clinical outcomes, is becoming a new standard in guiding individual patient therapy as well as for drug resistance surveillance. However, for most an…
Tafaj S, Mokrousov I, Borroni E, Trovato A, Kapisyzi P, et al.
Albania is a Balkan country with moderate to low incidence of tuberculosis (TB) and very low prevalence of drug resistant TB. Here, we analyzed a country-wide multi-year Mycobacterium tuberculosis collection in order to detect possible dynamic trends of TB in Albania, with a focu…