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Peiyu Xu, Shenni Liang, Andrew Hahn, Vivian Zhao, Wai Tung 'Jack' Lo, et al.
…forming public health strategies. However, existing genomic epidemiology simulators typically assume conditional independence among these processes: generating transmission trees independently of pathogen evolution, and then superimposing neutral mutations onto fixed genealogies …
Zongying Zhan, Tiancheng Xie, Tianshuo Zhao, Xiyu Zhang, Sihui Zhang, et al.
**OBJECTIVE:** To analyse temporal trends of respiratory infectious diseases (RIDs) in Baiyin City from 2014 to 2023, aiming to explore the epidemiological patterns of these diseases (tuberculosis, scarlet fever, pertussis, measles, influenza, mumps, varicella and rubella) and pr…
Cano-Portero R, Amillategui-Dos Santos R, Boix-Martínez R, Larrauri-Cámara A
The epidemiological surveillance data for tuberculosis in Spain in 2015 is analysed in this report. This information was gathered through cases reported to the Red Nacional de Vigilancia Epidemiológica [National Epidemiological Surveillance Network]. In addition, the update of th…
Carson J, Keeling M, Ribeca P, Didelot X
…nfluenza H7N7 in the Netherlands to reconstruct its spatial epidemiology. In both cases, we show that incorporating epidemiological data into the genomic analysis allows us to investigate the role of epidemiological properties in the spread of infectious diseases.
Jajou R, de Neeling A, van Hunen R, de Vries G, Schimmel H, et al.
Background Patients with Mycobacterium tuberculosis isolates sharing identical DNA fingerprint patterns can be epidemiologically linked. However, municipal health services in the Netherlands are able to confirm an epidemiological link in only around 23% of the patients with isola…
Goscé L, Tadesse AW, Foster N, van Kalmthout K, Rest JV, et al.
Background Digital adherence technologies (DATs) with associated differentiated care are potential tools to improve tuberculosis (TB) treatment outcomes and reduce associated costs for both patients and healthcare providers. However, the balance between epidemiological and econom…
Buenestado-Serrano S, Martínez-Lirola M, Dippenaar A, Sanz-Pérez A, Garrido-Cárdenas JA, et al.
The transition from MIRU-VNTR-based epidemiology studies in tuberculosis (TB) to genomic epidemiology has transformed how we track transmission. However, short-read sequencing is poor at analyzing repetitive regions such as the MIRU-VNTR loci. This causes a gap between the new ge…
Xiaoyu Lu, Yuan Jiang, Rui Zhang, Yangyi Zhang, Jing Li, et al.
**BACKGROUND:** Long-term transmission of multidrug-resistant tuberculosis (MDR-TB) challenges TB control by generating new cases and enabling the emergence of extensively resistant strains. We investigated its epidemiologic and bacterial drivers in Shanghai, China. **METHODS:**…
Asare P, Asante-Poku A, Osei-Wusu S, Otchere ID, Yeboah-Manu D
…, remains a global health problem. West Africa has a unique epidemiology of TB that is characterized by medium- to high-prevalence. Moreover, the geographical restriction of M. africanum to the sub-region makes West Africa have an extra burden to deal with a two-in-one pathogen. …
Jiomekong A, Camara G
Epidemiological surveillance systems enable collection, analysis and dissemination of information on the monitored disease to different stakeholders. It may be done manually or using a software. Given the poor performances of manual systems, the software approach is generally ado…
Sadovska D, Ozere I, Pole I, Ķimsis J, Vaivode A, et al.
Background Tuberculosis remains a global health threat, and the World Health Organization reports a limited reduction in disease incidence rates, including both new and relapse cases. Therefore, studies targeting tuberculosis transmission chains and recurrent episodes are crucial…
Guillén-Nepita AL, Vázquez-Marrufo G, Cruz-Hernández A, García-Oliva F, Zepeda-Gurrola RC, et al.
Tuberculosis control in developing regions with apparent low incidence, like the low-income Mexican state of Michoacán, with mean annual incidence rates below 10/100,000 inhabitants, requires knowledge of the actual behavior of the disease. This can be determined using an epidemi…
Jajou R, Kohl TA, Walker T, Norman A, Cirillo DM, et al.
BackgroundWhole genome sequencing (WGS) is a reliable tool for studying tuberculosis (TB) transmission. WGS data are usually processed by custom-built analysis pipelines with little standardisation between them.AimTo compare the impact of variability of several WGS analysis pipel…
Carlos Cifuentes-González, Germán Mejía-Salgado, William Rojas-Carabali, Josué Tovar-Tirado, Luis Alejandro Diez-Bahamón, et al.
… its clinical importance, the global incidence and detailed epidemiology of scleritis are poorly understood due to its heterogeneity and rarity. This systematic review and meta-analysis aim to elucidate the worldwide incidence and epidemiological trends of scleritis, examining va…
Zheng MQ, Li XX, Xu R, Liu S, Rui ZY, et al.
… literature study. In this study, publications on molecular epidemiology were analyzed using bibliometric analysis. The statistical analysis of influential publications, journals, countries and authors was first conducted. Methods The Web of Science database was searched for publ…
Rina de Zwaan, Gerard de Vries, Ella Ubbelohde, Arnout Mulder, Miranda Kamst-van Agterveld, et al.
Whole genome sequencing (WGS) is able to identify epidemiological links between Mycobacterium tuberculosis isolates. Recent clustering can be ruled out using a pre-defined single nucleotide polymorphism (SNP) threshold. If WGS clusters grow significantly over time limited genetic…
Nicola Harvey, Guy McGrath, James O'Shaughnessy, Jamie A Tratalos, Brian Byrne, et al.
… health, biosecurity and the economy. The complexity of bTB epidemiology, driven by multiple host species, undetected transmission and incomplete diagnostic sensitivity, makes surveillance and control challenging. Pathogen whole-genome sequencing (WGS) can clarify transmission dy…
Azger Dusthackeer, Mahizhaveni Balasubramanian, Sam Ebenezer Rajadas, Christy Rosaline Nirmal, Padmasini Elango, et al.
**INTRODUCTION:** The rise of drug-resistant tuberculosis poses a significant challenge in patient management. Epidemiological cut-off values define drug resistance in. In our previous study, we reported deviations from the WHO-recommended epidemiological cut-off values and ident…
Menean M, Scandale P, Apuzzo A, Barresi C, Checchin L, et al.
…-threatening inflammatory conditions. Understanding uveitis epidemiology, etiology, and clinical findings is fundamental for a prompt diagnosis and optimal patient management. The aim of the study is to report the epidemiology of uveitis in a national referral center in Northern …
Cheng B, Behr MA, Howden BP, Cohen T, Lee RS
…cs have become increasingly important in infectious disease epidemiology and public health. The Strengthening the Reporting of Molecular Epidemiology for Infectious Diseases (STROME-ID) guidelines were developed to outline a minimum set of criteria that should be reported in geno…
Han Z, Li J, Sun G, Gu K, Zhang Y, et al.
Background Multidrug-resistant tuberculosis (MDR-TB) has become a major public health problem in China, with mounting evidence suggesting that recent transmission accounts for the majority of MDR-TB. Here we aimed to reveal the transmission pattern of an MDR-TB outbreak in the Ji…
Ni X, Zhu C, Li Q, Jiang H, Liu J, et al.
…where the tuberculosis incidence rate is high. However, the epidemiology characteristics of M. tuberculosis L4 in China remain poorly understood. Here, the 15-loci Variable number of tandem repeats (VNTR) patterns of 975 L4 isolates from a National Survey of Tuberculosis in China…
Rito T, Matos C, Carvalho C, Machado H, Rodrigues G, et al.
…episodes of transmission, mostly undetected using classical epidemiology alone. Conclusions Although control policies have been successful in decreasing incidence in Porto, the discerned complexity suggests that, for elimination to be a realistic goal, strategies need to be adjus…
Chisompola NK, Streicher EM, Muchemwa CMK, Warren RM, Sampson SL
… drug resistance AND Africa AND (spoligotyping OR molecular epidemiology OR IS6110 OR MIRU OR DNA fingerprinting OR RFLP OR VNTR OR WGS)" were used to identify relevant articles reporting the molecular epidemiology of drug resistant TB in Africa. Results Diverse genotypes are ass…
Dixit A, Ektefaie Y, Kagal A, Freschi L, Karyakarte R, et al.
…orld's burden, are not well studied. We conducted a genomic epidemiology study to compare epidemiological success, host factors, and drug resistance among the 4 major Mycobacterium tuberculosis (Mtb) lineages (L1-L4) circulating in Pune, India. Methods We performed whole-genome s…