Showing 1–12 of 12 documents
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Randall P, Esmail A, Wilson L, Makambwa E, Pooran A, et al.
…h diagnostic accuracy. However, DNA-based diagnostic tests (GeneXpert Ultra), more sensitive than an earlier versions, have recently become available. Given that the diagnosis of TBP is challenging, we performed a comparative diagnostic accuracy study comparing both assays. Metho…
Sharma K, Sharma M, Sharma A, Dhillon MS
…(TruPlus), a chip-based portable machine, was compared with GeneXpert Ultra (GxUltra) for diagnosing drug-resistant OATB. Design 115 synovial fluid and pus specimens [22 culture-positive confirmed, 58 culture-negative clinically-suspected, 35 non-TB controls] processed between 20…
Liu R, Liang Q, Shang Y, Ma Y, Wang F, et al.
…from digestive tract. We aimed to assess the performance of GeneXpert on stool and gastric lavage fluid (GALF) in diagnosing TB among patients with severe pulmonary TB. Methods We enrolled adults with suspected pulmonary TB who were unable to produce sputum at visit between Janua…
Ai JW, Zhou X, Xu T, Yang M, Chen Y, et al.
…. Its diagnostic performance was compared, in parallel with culture and the GeneXpert MTB/RIF assay (Xpert). The CRISPR-MTB test is highly sensitive with a near single-copy sensitivity, demands less sample input and offers shorter turnaround time than Xpert. When evaluated in the…
Ma J, Wang L, Zheng X, Cui H, Sha W
…ronchoalveolar lavage fluid was collected for mycobacterial culture and acid-fast staining, GeneXpert MTB/RIF, and DGPMC assay. The diagnostic performance of DGPMC assay was evaluated against the composite reference standard. Results Overall, 240 patients were included in this tr…
Buchera FS, Silago V, Japhet G, Mtemisika CI, Damiano P, et al.
…uberculosis (TB) at selected hospitals in Mwanza, Tanzania. GeneXpert and conventional bacteriological culture and sensitivity were used for the detection of TB and other pathogenic bacteria, respectively. STATA version 13.0 was used for data analysis. The median (IQR) age of par…
Chang Y, Zhang M, Liu G, Wu X, Yan Q, et al.
…tudy showed that TB nestMIRA performed slightly better than GeneXpert MTB/RIF (Xpert) (85.27% vs. 82.17%) and significantly better than culture (55.81%) and acid-fast bacillus (AFB) smear (38.76%). The TB nestMIRA assay offers speed, specificity, sensitivity, and convenience. We …
Cao J, Gu Y, Wu XC, Cheng LP, Wang L, et al.
…eolar lavage fluid (BALF) with acid-fast staining, MGIT 960 culture, pathological examination, and Xpert for isolated pulmonary nodules caused by MTB infection were compared using receiver operating characteristic (ROC) analysis. Results There were 135 patients, 64 with isolated …
Soheila Shaghaghian, Narsis Ghahramani, Erfan Sadeghi, Zahra Zarei, Sina Nasrollahian, et al.
…here is controversy regarding the indications of conducting GeneXpert assay for patients suspected of tuberculosis (TB). Therefore, we compared the accuracy of the assay between patients with and without positive results of acid-fast bacilli (AFB) smear and HIV. **METHOD:** The …
Seth B, Bernardo J, Sulis C
… infection isolation (AII). The US FDA approved the Cepheid GeneXpert-MTB-Rif® to support removing patients from AII. The FDA requires that “either one or two” separate sputum specimens be examined. To clarify this statement, the National Tuberculosis Controllers’ Association and…
Chaisson LH, Duong D, Cattamanchi A, Roemer M, Handley MA, et al.
…mplementation of a sputum molecular testing algorithm using GeneXpert MTB/RIF (Xpert; Cepheid) to guide discontinuation of isolation. Main outcomes and measures We measured the proportion of patients with molecular testing ordered and completed; the accuracy of the molecular test…
Hickey AJ, Cummings MJ, Zafari Z, Louh IK, Li J, et al.
…berculosis (MTB) to reduce risk of nosocomial transmission. GeneXpert MTB/RIF (Xpert) is more rapid and accurate than sputum smear microscopy, but it is not routinely used to 'rule out' infectious pulmonary TB among hospitalized patients in the United States. We sought to evaluat…