Showing 1–25 of 130 documents
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Chisompola NK, Streicher EM, Muchemwa CMK, Warren RM, Sampson SL
… drug resistance AND Africa AND (spoligotyping OR molecular epidemiology OR IS6110 OR MIRU OR DNA fingerprinting OR RFLP OR VNTR OR WGS)" were used to identify relevant articles reporting the molecular epidemiology of drug resistant TB in Africa. Results Diverse genotypes are ass…
Che Y, Li X, Chen T, Lu Y, Sang G, et al.
…ealth concern in Ningbo, China. Understanding its molecular epidemiology and spatial distribution is paramount for effective control. Methods From December 24, 2020, to March 12, 2023, we collected clinical Mycobacterium tuberculosis (MTB) strains in Ningbo, with whole-genome seq…
Loukman M, Olivier B, Vincent B, Rachid D, Cyril F, et al.
…nual deaths for 10 million cases. Little is known about the epidemiology of tuberculosis and its resistance in Reunion Island, which is at the heart of migratory flows from highly endemic Indian Ocean territories. Methods We carried out a retrospective observational study of case…
Xu Y, Li Q, Zhu M, Wu X, Wang D, et al.
The aim of this study was to investigate the epidemiological characteristics and profile of drug-resistant tuberculosis (DR-TB) among children with TB in Sichuan province of China.From January 2015 to December 2018, microbiological culture-confirmed child TB cases (aged <15 years…
Xiaoyu Lu, Yuan Jiang, Yanping Liu, Junhong Chen, Yinglin Lao, et al.
Tuberculosis (TB), particularly extremely drug-resistant TB (EDR-TB), remains a significant public health concern worldwide. Understanding the transmission patterns and epidemiological characteristics of EDR-TB is vital for effective disease control. Between 1 January 2006 and 31…
Mizukoshi F, Kobayashi N, Kirikae F, Ohta K, Tsuyuguchi K, et al.
…operties of drug-resistant tuberculosis in Japan. Molecular epidemiology provides several clues to inform potential measures to control drug-resistant tuberculosis in Japan.
Lei Ji, Feilin Ren, Deshun Xu, Xiaohua Zhu, Zhaowei Tong, et al.
…SNP threshold) were conducted to characterize the molecular epidemiology of TB in this region. **RESULTS:** Lineage 2.2.1 (Beijing genotype) was predominant (80.0%). A total of 86 isolates (24.6%) harbored drug resistance-associated mutations, including 2.0% MDR-TB and 1.7% pre-…
Dzeyie KA, Basu S, Dikid T, Bhatnagar AK, Chauhan LS, et al.
Background Multidrug-resistant tuberculosis (MDR-TB) is a major public health challenge in India. It is associated with poor treatment outcomes, multiple adverse effects to treatment and involves enormous social and economic losses. The objective of the study was to ascertain the…
Tiberi S, Utjesanovic N, Galvin J, Centis R, D'Ambrosio L, et al.
…eview is to inform the reader on the latest developments in epidemiology, diagnostics and management. Epidemiology Drug-resistant Tuberculosis (DR-TB) continues to be a current global health threat, and is defined by higher morbidity and mortality, sequelae, higher cost and compl…
Dohál M, Dvořáková V, Šperková M, Porvazník I, Cabibbe AM, et al.
Objective The resistance of Mycobacterium ( M. ) tuberculosis to antituberculosis drugs poses a major threat to global public health. Whole genome sequencing (WGS) is an increasingly preferred method in the diagnostics and monitoring of the transmission dynamics of resistant form…
Luis M Rodríguez-Martínez, Jose L Chavelas-Reyes, Carlo F Medina-Ramírez, Eli Fuentes-Chávez, Zurisaday S Muñoz-Troncoso, et al.
…f drug-resistant strains. This work addresses the molecular epidemiology of TB in the Mexican context, emphasizing its role in understanding transmission, genetic diversity, and resistance mechanisms. To achieve this, we reviewed molecular typing approaches including spoligotypin…
Bhering M, Kritski A
This study aimed to reinforce the importance of the epidemiological surveillance of multidrug-resistant tuberculosis (MDR-TB) in Rio de Janeiro State (RJ). Here, we reviewed seven articles we published between 2018 and 2022. This study had two phases. The quantitative phase where…
Wang DM, Li QF, Zhu M, Wu GH, Li X, et al.
Background Sichuan is a province located in southwestern China, which have a higher incidence of tuberculosis (TB). This study aimed to analyze the epidemiological and clinical characteristics, as well as drug resistance in culture-confirmed children with Tuberculosis meningitis …
Riccardi N, Pontarelli A, Alagna R, Saderi L, Ferrarese M, et al.
Objective We evaluated the epidemiology and treatment outcomes of multi-drug-resistant (MDR) and pre-extensively-resistant (pre-XDR) tuberculosis (TB) in migrants at two TB reference centers in Italy. Study design Patient selection criteria for the present study were as follows: …
Chen Y, Liu J, Zhang Q, Wang Q, Chai L, et al.
…d SDI. These findings contribute to our understanding of TB epidemiology and can inform public health strategies for prevention and management.
Tiberi S, Tiberi S, Zumla A, Migliori GB
…ealth care continue to hamper efforts. This article reviews epidemiology, clinical features, management, and treatment, with new updates and recent changes in guidelines that offer patients better tolerated and shorter regimens for enabling therapeutic outcomes.
Afsaneh Kaffash, Saeideh Sadat Shobeiri, Elham Pouraslan, Asghar Kazemzadeh, Fatemeh Doost Mohammadi, et al.
**OBJECTIVE:** This ecological study examines epidemiological trends in tuberculosis, multidrug-resistant TB, extensively drug-resistant TB, and latent TB infection across Iran and its provinces from 1990 to 2021, and explores their association with the Human Development Index. …
Couvin D, Reynaud Y, Rastogi N
The East African Indian (EAI) and Central Asian (CAS) lineages of Mycobacterium tuberculosis complex (MTBC) mainly infect tuberculosis (TB) patients in the eastern hemisphere which contains many of the 22 high TB burden countries including China and India. We investigated if phyl…
Neel R Gandhi, Kogieleum Naidoo, Keeren Lutchminarain, Shaheed V Omar, Hikari Yoshii, et al.
**RATIONALE:** Transmission is the primary driver of tuberculosis (TB) and drug-resistant (DR) TB in high-burden countries; however, where and between whom spread occurs is poorly understood. **OBJECTIVE:** We conducted universal whole genome sequencing (WGS) to evaluate the rol…
Fadzil FA, Ramli SR, Neoh H
…s the timeline of pulmonary tuberculosis (PTB) in Malaysia, epidemiology, management and outlook of the disease in the country. PTB was first reported in Malaya in the early 20th century and caused high morbidity and mortality. With the establishment of the National TB Control Pr…
Agata Maciejak-Jastrzębska, Grażyna Sygitowicz, Sylwia Brzezińska, Kinga Bielska, Ewa Augustynowicz-Kopeć
…logical and structural characteristics of mycobacteria; the epidemiology of the disease; and the role of the main diagnostic methods; with a particular focus on molecular methods and MALDI-TOF MS. This paper highlights their advantages and limitations and discusses their implicat…
Diriba G, Alemu A, Yenew B, Tola HH, Gamtesa DF, et al.
Objectives To estimate the pooled proportion of extensively drug-resistant tuberculosis (XDR-TB) and pre-extensively drug-resistant tuberculosis (pre-XDR-TB) in patients with multidrug-resistant TB (MDR-TB). Methods We systematically searched articles from electronic databases: M…
Ibrahim Khalil, Noshin Anjum Tasmi, Md Imran Hossain, Mst Mahmuda Akter
**BACKGROUND:** HIV/AIDS and multidrug-resistant tuberculosis (MDR-TB, non-extensively drug-resistant) together cause significant mortality in Africa, home to 67% of the 39 million people living with HIV globally and 2.5 million TB cases in 2022. This study analyzes Global Burden…
Hurtado J, Coitinho C, Nin N, Buroni M, Hurtado FJ, et al.
Human tuberculosis is still a major world health concern. In Uruguay, contrary to the world trend, an increase in cases has been observed since 2006. Although the incidence of MDR-resistant strains is low and no cases of XDR-TB were registered, an increase in the number of patien…
Guo H, An J, Li S, Ding B, Zhang Z, et al.
Background In this study, we utilized whole genome sequencing (WGS) of clinical extremely drug-resistant tuberculosis (EDR-TB) strains collected during 2014-2020 in Beijing to detect clustered strains. Methods A retrospective cohort study was conducted by inclusion of EDR-TB pati…