Showing 151–175 of 200 documents
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Chai M, Shi Q
Background Lung tuberculosis (TB) and lung cancer have a complex relationship. Data concerning TB treatment in lung cancer patients are still incomplete. The aim of this study was to investigate the effects of anti-cancer and anti-tuberculosis treatments in lung cancer patients w…
Ababu DG, Gobena WE, Getahun AM
Background Tuberculosis (TB) is a potentially serious infectious disease that mainly affects the lungs. The bacteria, Mycobacterium tuberculosis (MTB), that cause tuberculosis are spread from one person to another person through tiny droplets released into the air via coughs and …
Nunemo MH, Gidebo KD, Woticha EW, Lemu YK
Introduction Non-communicable diseases are comorbid with tuberculosis, however only a few record review based studies have been conducted, which are more concentrated on elevated glucose levels. This study aimed to assess non-communicable disease comorbidity and its predictors am…
Yanti B, Hadi S, Harrika F, Shehzad A
…g due to tension pneumothorax. It is a rare complication in tuberculosis cases with highly variable in clinical manifestations and persistent air leaks which might lead to complications such as empyema. Herein, we present a tuberculosis and diabetic patient complicated with giant…
Kusunoki T, Homma H, Kidokoro Y, Yoshikawa A, Tanaka K, et al.
A case of nasopharyngeal tuberculosis with cervical lymph node tuberculosis is reported. The patient was a 20-year-old female immigrant from Vietnam and cook apprentice. Her chief complaint was left neck swelling with pain for three months. She was diagnosed with left neck lympha…
Tiruneh G, Getahun A, Adeba E
…s a prophylactic treatment used in the prevention of active tuberculosis. It is known to be most effective in preventing tuberculosis in patients with positive tuberculin skin test. Methods A retrospective cohort study centering on two institutions in Nekemte town, Western Ethiop…
Kiwanuka N, Zalwango S, Kakaire R, Castellanos ME, Quach THT, et al.
Background The persistence of tuberculosis today and its global disparity send a powerful message that effective tuberculosis control must respond to its regional epidemiology. Active case finding through contact investigation is a standard protocol used for tuberculosis control,…
Williams V, Calnan M, Edem B, Onwuchekwa C, Okoro C, et al.
…rollout of GeneXpert aimed at increasing early diagnosis of tuberculosis to improve treatment outcomes and global tuberculosis targets. Objective This study evaluated trends in tuberculosis diagnosis and outcomes pre- and post-introduction of GeneXpert in three African countries …
The “WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection, third edition” is the latest document replacing the one issued in 2021. This latest edition includes new recommendations on the use of a new class of diagnostic t…
Sgrò A, Ots R, Brunetti E
BACKGROUND: Tuberculosis (TB) is the ninth leading cause of death worldwide. World Tuberculosis Day is held every year to increase global awareness of TB. OBJECTIVE: To quantify the impact of World Tuberculosis Day using Internet-based data. METHODS: Google Trends™ data were used…
Ayalew S, Habtamu G, Melese F, Tessema B, Ashford RT, et al.
Background Tuberculosis (TB) is a major cause of ill health and one of the leading causes of death worldwide, caused by species of the Mycobacterium tuberculosis complex (MTBC), with Mycobacterium tuberculosis being the dominant pathogen in humans and Mycobacterium bovis in cattl…
Maqsood R, Duffy SC, Bin Rashid H, Gill SS, Jabeen C, et al.
Bovine tuberculosis (bTB), traditionally associated with Mycobacterium bovis , presents significant public health and economic challenges worldwide. This study investigated the causative agents of bTB in slaughtered cattle and buffalo in Lahore, Pakistan. Of the 3,581 animals scr…
Starshinova A, Dovgalyk I, Malkova A, Zinchenko Y, Pavlova M, et al.
Immunological testing for tuberculosis has been one of the most rapidly developing areas in the last decade. A new-generation immunological skin test, Diaskintest (DST), has been developed in the Russian Federation and successfully implemented into clinical practice since 2009. T…
Ranaivomanana P, Ratovoson R, Razafimahatratra C, Razafimahefa A, Hoffmann J, et al.
…e functions and increases the risk of developing the active tuberculosis (TB) symptoms in exposed women. The effect of pregnancy on the Mycobacterium tuberculosis- specific immune responses used for most of the TB immunodiagnostic assays is not well documented. Here we investigat…
Sharma P, Anthwal D, Kumari P, Gupta RK, Lavania S, et al.
Abdominal tuberculosis (ATB) continues to pose a major diagnostic challenge for clinicians due to its nonspecific clinical presentation, variable anatomical location and lack of sensitive diagnostic tools. In spite of the development of several assays till date; no single test ha…
Reedoy KS, Loots DT, Beukes D, Reenen MV, Pillay B, et al.
…on A clear understanding of the metabolome of Mycobacterium tuberculosis and its target host cell during infection is fundamental for the development of novel diagnostic tools, effective drugs and vaccines required to combat tuberculosis. The surface-located Mycobacterium tubercu…
Ren N, JinLi J, Chen Y, Zhou X, Wang J, et al.
Mycobacterium tuberculosis (M. tuberculosis) regions of difference (RD) encode proteins which are potentially useful as diagnostic reagents for tuberculosis (TB). In this study, 75 genes from M. tuberculosis RD1-RD16 were successfully cloned from which 68 proteins were expressed …
Tesfaye S, Zerfu B, Desta K
Background Intestinal parasites and Tuberculosis (TB) co-infection is a major public health problem. The parasitic infection suppresses the cell mediated immunity that protects tuberculosis. Helminthes-induced immune modulation promotes progression to active tuberculosis. However…
Ntivuguruzwa JB, Michel AL, Kolo FB, Mwikarago IE, Ngabonziza JCS, et al.
Background Bovine tuberculosis (bTB) is an endemic disease in Rwanda, but little is known about its prevalence and causative mycobacterial species. The disease causes tremendous losses in livestock and wildlife and remains a significant threat to public health. Materials and meth…
Tafess K, Beyen TK, Girma S, Girma A, Siu G
Background Tuberculosis remains a serious public health concern globally. The enormous social, economic, and health impacts of the diseases are attributed to the lack of updated data on the prevalence, geospatial distribution, population structures, and genotypic variants of the …
Huang K, Zhou H, Chen M, Chen R, Wang X, et al.
Tuberculosis(TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb) infections, remains the leading cause of mortality from a single infectious agent globally. The progression of tuberculosis disease is contingent upon the complex interplay between the host's immun…
Zhen J, Zhang C, Huang T, Xie L, Yan Y, et al.
The surge of drug-resistant Mycobacterium tuberculosis (DR-TB) impedes the World Health Organization's efforts in ending TB and calls for new therapeutic formulations. M. tuberculosis sirtuin-like protein Rv1151c is a bifunctional enzyme with both deacetylation and desuccinylatio…
Zhang X, Tian Y, Shi Y, Liu J, Zhao C, et al.
…te of the development of diagnostic tests for Mycobacterium tuberculosis ( M. tuberculosis ), the etiological agent of tuberculosis, there has remained a gap between the established methods and an easily accessible diagnostic test, particularly in developing and resource-poor are…
Kato A, Mashiba T, Tateishi Y, Oda R, Funakoshi H, et al.
…ominal tuberculous lymphadenopathy. Iatrogenic disseminated tuberculosis is also rare. Herein, we present a rare case of peripancreatic tuberculous lymphadenopathy with ruptured duodenal varices due to portal vein obstruction. The patient presented to our hospital with hematemesi…
Dai W, Ma L, Cao Y, Wu D, Yu T, et al.
…lasmic sperm injection (ICSI) outcome in women with genital tuberculosis (GTB). Methods: One hundred and fifty-five women with genital tuberculosis constituted the study group (Group A), consisting of 25 patients with endometrial tuberculosis (Group A1) and 130 patients with tuba…