Showing 151–175 of 200 documents
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Kaba Ö, Kara M, Odacılar CA, Kamer İ, Sütçü M, et al.
Aim Extrapulmonary tuberculosis is observed more frequently and leads to complications with a higher rate in children compared with adults because the risk of lymphohematogen spread is higher. In this study, the clinical, laboratory, and radiologic findings and treatment outcomes…
Igbokwe V, Ruby LC, Sultanli A, Bélard S
…2020, an estimated total of 155 million people had survived tuberculosis. Among this number, a sizable proportion have considerable post-tuberculosis morbidity, as shown for the adult population. This systematic review aims to identify the spectrum and prevalence of post-tubercul…
Duffy SC, Srinivasan S, Schilling MA, Stuber T, Danchuk SN, et al.
Background Zoonotic tuberculosis is defined as human infection with Mycobacterium bovis . Although globally, India has the largest number of human tuberculosis cases and the largest cattle population, in which bovine tuberculosis is endemic, the burden of zoonotic tuberculosis is…
Rodgers MA, Ameel C, Ellis-Connell AL, Balgeman AJ, Maiello P, et al.
Tuberculosis (TB), caused by Mycobacterium tuberculosis , is the leading cause of death among human immunodeficiency virus (HIV)-positive patients. The precise mechanisms by which HIV impairs host resistance to a subsequent M. tuberculosis infection are unknown. We modeled this c…
Ait Ouaaziz N, El Bakkali M, El Yahyaoui O, Bejja F, Taboz Y, et al.
Introduction Tuberculosis, a global major concern, causes millions of deaths annually despite WHO strategies. A persistent gap in detection and treatment facilitates rapid spread in high-burden countries. Aims Analyze the clinical-epidemiological profile of tuberculosis patients …
Chen RY, Yu X, Smith B, Liu X, Gao J, et al.
Background Direct bronchial spread of tuberculosis was extensively described in pre-antibiotic human pathology literature but this description has been overlooked in the post-antibiotic era, in which most pathology data come from animal models that emphasise the granuloma. Modern…
Zhang Z, Zong X, Liu Z, Dong X, Bai H, et al.
Background Tuberculosis remains an infectious disease of global concern, with potential impacts on respiratory and intestinal microbiota owing to prolonged broad-spectrum antibiotic therapy. Despite its potential to cause infertility, the vaginal microbiota of women with genital …
Meregildo-Rodriguez ED, Asmat-Rubio MG, Vásquez-Tirado GA
Tuberculosis is a rising global public health emergency. Then, it is a priority to undertake innovations in preventive, diagnostic, and therapeutic methods. Improved diagnostic methods for tuberculosis are urgently needed to address this global epidemic. These methods should be r…
Singh GR, Sinha A, Anushweta, Sharma R, Saurabh K, et al.
Background Pulmonary tuberculosis may result in haematogenous and lymphatic extension in case of failure of early detection, or immunocompromised status, leading to extrapulmonary tuberculosis. Rare sites of extrapulmonary tuberculosis include the gastrointestinal tract, musculos…
Alaoui Z, Raiteb M, Ihbibane F, Soraa N, Tassi n
Abstract Background Tuberculosis is a health problem in Morocco, which is increasingly indicative of human immunodeficiency virus (HIV) infection. Objective To determine the epidemiological, clinical and paraclinical, therapeutic and evolutionary aspects of tuberculosis and HIV c…
Awang H, Nik Husain NR, Abdullah H
…es We sought to determine the total proportion of pediatric tuberculosis cases, characterize tuberculosis by its anatomical location and pretreatment sputum smear status, and to determine the association of the sociodemographic and clinical factors with tuberculosis disease among…
Wang W, Wang X, Chen S, Li J, Cheng Q, et al.
…comorbidities among patients with newly diagnosed pulmonary tuberculosis and assess the impact of comorbidities on the clinical characteristics of patients. Methods This study was conducted in 13 hospitals across 13 counties in Zhejiang province, China. Patient data collected in …
Mikashmi Kohli, Leeberk Raja Inbaraj, Angela Salomon, Katie Scandrett, Alexei Korobitsyn, et al.
…sts widely used for simultaneous detection of Mycobacterium tuberculosis complex and rifampicin resistance in sputum. To extend our previous review on extrapulmonary tuberculosis, we performed this update to inform a WHO policy update. **OBJECTIVES:** To estimate the diagnostic …
Spatola M, Nziza N, Irvine EB, Cizmeci D, Jung W, et al.
Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), remains a global health burden. While M. tuberculosis is primarily a respiratory pathogen, it can spread to other organs, including the brain and meninges, causing TB meningitis (TBM). However, little is known …
Dellal M, Batoui S, Chetoui A, Kanouf M, Fatihi T, et al.
Background Tuberculosis remains a major global health concern and a leading cause of mortality. In Morocco, various forms of extrapulmonary tuberculosis are prevalent. This systematic review examines research findings on the prevalence, risk factors, and treatment outcomes of ext…
Eddabra R, Neffa M
…ajor strides in the prevention, diagnosis and management of tuberculosis, the disease continues to be one of the most pressing global health problems, particularly in developing countries. The purpose of the present study was to describe the epidemiological profile among tubercul…
Abdu M, Balchut A, Girma E, Mebratu W
Background Tuberculosis (TB) is a major global public health problem. The disease is a leading cause of morbidity and mortality in Ethiopia. Early identification of cases and commencement of effective chemotherapy is an effective method to control the spread of tuberculosis. Dela…
Zanaa A, Paramita SA, Erdenee O, Tsolmon B, Purevdagva A, et al.
Mongolia was listed among the 30 countries with a high tuberculosis burden in 2021. Approximately 10-11% of the tuberculosis cases are of children, which is higher than the global average (6.0%). As children are a vulnerable population, it is important to understand the current s…
He J, Xiong J, Huang Y
Background The timely diagnosis of tuberculosis through innovative biomarkers that do not rely on sputum samples is a primary focus for strategies aimed at eradicating tuberculosis. miR-29 is an important regulator of tuberculosis pathogenesis. Its differential expression pattern…
Ndege R, Weisser M, Elzi L, Diggelmann F, Bani F, et al.
Background Patients with suspected tuberculosis are often overtreated with antituberculosis drugs. We evaluated the diagnostic value of the focused assessment with sonography for HIV-associated tuberculosis (FASH) in rural Tanzania. Methods In a prospective cohort study, the freq…
Chaudhry D, Tyagi D
… causes of severe pneumonia. The most common indication for tuberculosis-related ICU admission is acute respiratory failure due to pneumonia or acute respiratory distress syndrome (ARDS) (with or without miliary tuberculosis) followed by septic shock with multiple organ dysfuncti…
Wu F, Yang B, Xiao Y, Ren LL, Chen HY, et al.
Background Tuberculosis is a chronic infectious disease and an important public health problem. Despite progress in controlling tuberculosis, the incidence of tuberculosis in China is still very high, with 895000 new cases annually. This case report describes the investigation of…
Sundaram K, Vajravelu LK
Mycobacterium tuberculosis causes tuberculosis, a fatal infection resulting in widespread illness and death. In 2020, approximately 10 million people were diagnosed with tuberculosis. The top 30 tuberculosis-endemic countries accounted for 86% of all estimated occurrence cases wo…
Zhang Y, Chen S, Wei H, Zhong Q, Yuan Y, et al.
…abinomannan (LAM) test (chemiluminescence-based) for active tuberculosis in the general population. A retrospective study was conducted on 250 clinical suspected tuberculosis patients who were HIV-negative and visited the Fourth People's Hospital of Foshan from January 2022 to De…
Yang C, Wang T, Guo Y, Zeng Y, Gao W
…nd The World Health Organization predicted 10.6 million new tuberculosis cases and 1.5 million deaths in 2022. Tuberculous meningitis, affecting 1% of active TB cases, is challenging to diagnose due to sudden onset, vague symptoms, and limited laboratory tests. Nanopore-targeted …