Showing 151–175 of 200 documents
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Fritschi N, Schmidt AJ, Hammer J, Ritz N
Background In Europe, surveillance and monitoring of pediatric tuberculosis (TB) remains important, particularly in the light of migration in recent years. The aim of the study was to evaluate incidence rates of childhood TB and detailed diagnostic pathways and treatment. Methods…
Sahito A, Fatmi Z, Kadir MM, Arif F
Background: Estimated 1.1 million children developed tuberculosis (TB) globally in 2020. Household air pollution has been associated with increased respiratory tract infections among children. Nonetheless, there are scarce data regarding the association of indoor environment with…
Gupta S, Vats P, Jha A, Singh K, Ghosh S, et al.
…of the study was to evaluate the gingival manifestations of tuberculosis (TB) in the oral cavity in pediatric patients. Study design Four pediatric patients were enrolled in the study. Clinical symptoms, auxiliary examinations, treatments, and outcomes were recorded and analyzed.…
Oana Mariana Mihailov, Loredana Stavăr Matei, George Țocu, Valerii Luțenco, Cosmin George Popovici, et al.
**BACKGROUND:** Tuberculosis (TB) in children is associated not only with infectious burden but also with potential psychological distress, which remains insufficiently explored. The aim of this study was to evaluate the pattern and evolution of depressive symptoms in pediatric T…
Abdou Natali Bassirou, Yacouba Abdourahamane, Ounoussa Tapha, Laouali Maman Mourtala, Boureima Hassane, et al.
**BACKGROUND:** Pediatric tuberculosis is challenging to diagnose due to the limited presence of bacteria and difficulties in obtaining high-quality sputum samples. This study assessed the effectiveness of stool samples versus gastric contents analyzed with GeneXpert Ultra for di…
Chu P, Chang Y, Zhang X, Han S, Jin Y, et al.
ABSTRACT Pediatric tuberculosis (TB) is a serious infectious disease that affects many children worldwide and is more likely to be extrapulmonary than adult TB. However, the clinical and epidemiological profile, and cost burden of pediatric extrapulmonary TB (EPTB) in China remai…
Bilal Aslam, Faiza Farooq, Shafiq Ur Rahman, Fazeela Bibi, Umama Alam, et al.
Spinal tuberculosis, also known as Pott's disease, in children is a rare manifestation of extrapulmonary tuberculosis. The nonspecific clinical features, such as chronic abdominal pain, of extrapulmonary TB or spinal TB in children tend to delay diagnosis. We present the case of …
Çay Ü, Alabaz D, Gündeşlioglu ÖÖ, Mirioglu A, Pehlivan UA
Background Skeletal tuberculosis is rarely seen among extrapulmonary tuberculosis, especially in childhood because the diagnosis may be delayed for years due to diagnostic difficulties. In this study, it was aimed to evaluate the clinical characteristics, methods used in diagnosi…
Shekar P A, Patel H, Dumra A, Reddy D, Shivakumar KS, et al.
Background Urogenital tuberculosis (UGTB) has traditionally being a diagnosis of adulthood and is supposed to be rare in children, as it is believed that the symptoms of renal tuberculosis do not appear for 10 or more years after the primary infection. While this may be true in d…
Amin AG, De P, Graham B, Jensen BL, Moreau E, et al.
The World Health Organization (WHO) emphasizes that tuberculosis (TB) in children and adolescents is often overlooked by healthcare providers and difficult to diagnose. As childhood TB cases rise, finding a diagnostic high in sensitivity and specificity is critical. In this study…
Starshinova A, Zhuravlev V, Dovgaluk I, Panteleev A, Manina V, et al.
Background The WHO strategy for eradication of tuberculosis (TB) by 2035 (The End TB Strategy) is aimed at an early and precise diagnosis and subsequent effective treatment of TB patients. Currently, there is no gold standard for the diagnosis of latent TB infection. This study e…
Siddalingaiah N, Chawla K, Nagaraja SB, Hazra D
Pediatric tuberculosis is a major cause of mortality and morbidity in children due to high transmission, poor diagnostic tools, and various respiratory diseases mimicking TB. Identifying risk factors will provide evidence for clinicians to strongly relate their diagnosis to the a…
Bulterys MA, Wagner B, Redard-Jacot M, Suresh A, Pollock NR, et al.
Most diagnostic tests for tuberculosis (TB) rely on sputum samples, which are difficult to obtain and have low sensitivity in immunocompromised patients, patients with disseminated TB, and children, delaying treatment initiation. The World Health Organization (WHO) calls for the …
Vieira JL, Foschiera L, Ferreira ICS, Chakr VCBG
…e/ADA ratio, and the LDH/ADA ratio in pleural fluid for the diagnosis of pleural tuberculosis (PT) in children and adolescents. Methods This was a retrospective cross-sectional study conducted at a tertiary hospital in a high-tuberculosis-incidence area, between 2001 and 2018. Al…
Bhatt C, Prabhu SP, Parihar A
Central nervous system tuberculosis (CNS TB) is the most dreaded manifestation of systemic tuberculosis in the pediatric age group. It is associated with high morbidity and mortality due to severe neurological complications and sequelae. Knowledge about the imaging spectrum of CN…
Vega Pangaribuan, Muhammad Arifin Parenrengi, Wihasto Suryaningtyas
…e literature on the clinical presentation and management of pediatric cervical spine tuberculosis (CST) and evaluate the outcomes of conservative or surgical treatment based on anatomical location (craniovertebral junction [CVJ], subaxial, and cervicothoracic junction). **METHOD…
Dubois M, Dixit A, Lamb G
…plantation are at high risk of morbidity and mortality from tuberculosis (TB) disease in the post-transplant period. Treatment of TB infection and disease in the post-transplant setting is complicated by immunosuppression and drug interactions. There are limited data that address…
Muhammad Abubaker Tobaiqi, Musleh Naser Alshamrani, Shyamkumar Sriram, Ahmad Bakur Mahmoud, Hammad Ali Fadlalmola, et al.
: The world health goal of eliminating tuberculosis (TB) is heavily hinged on timely and efficient diagnosis and treatment. The interferon-γ release assays (I.G.R.A.s) can diagnoseinfection and offer an alternative to the centuries-old tuberculin skin test (T.S.T.). Yet the…
Das A, Anupurba S, Mishra OP, Banerjee T, Tripathi R
Introduction Childhood tuberculosis (TB) is now a global priority. With the advent of Xpert MTB/RIF, more TB cases in children are being reported. This study was undertaken to evaluate the performance of Xpert in diagnosis of pulmonary and extra-pulmonary TB in children. Methods …
Javeria Javed, Muhammad Osama Khan, Fatima Zahra, Rashida Abbas Fakhruddin Lacewala, Maryam Aftab, et al.
**OBJECTIVE:** Abdominal tuberculosis (AbTB) is an extrapulmonary manifestation of tuberculosis (TB) that remains difficult to diagnose because its symptoms resemble many other gastrointestinal disorders. This study aimed to describe the clinical presentation, diagnostic evaluati…
Jia J, Chen D, Liu L, Siddiqui MJ, Yang F, et al.
Background China has a high burden of tuberculosis and latent tuberculosis infection (LTBI). The aim of this study was to estimate the prevalence of LTBI among healthy young children and adolescents and test a 2-step approach to explore the threshold for the diagnosis of tubercul…
Pérez-Butragueño M, Ramos-Rincón JM, Tesfamariam A, Comeche B, Mohammed N, et al.
… This study assesses the impact of the Xpert MTB/RIF in the diagnosis of childhood tuberculosis (TB) in a rural hospital in a resource-constrained setting. Methods Retrospective cross-sectional study in children evaluated for presumptive TB from 1 June 2016 to 31 May 2017 at the …
Agarwal A, Mathur SB
Tuberculosis (TB) remains a significant public health concern, especially in children. The World Health Organization now provides estimates on pediatric TB cases and deaths, underscoring the urgency of addressing this issue. In India, childhood TB contributes significantly to the…
Zhang Y, Tao Y
Pancreatic tuberculosis (TB) is an uncommon form of extrapulmonary TB and represents a diagnostic challenge for physicians. Pancreatic TB presents with nonspecific signs and symptoms and may mimic malignancy. However, pancreatic TB rarely occurs in children. Here, we present a ca…
Gupta S, Parihar A, Singh S, Agarwal A, Agarwal S
Introduction Despite tuberculosis being rampant in the Indian subcontinent, most cases of osteoarticular (OA) tuberculosis (TB) are missed until significant bony destruction has occurred. Initial presentation of extra-pulmonary TB mimics many other disease entities while many dis…