Showing 151–175 of 200 documents
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K Ma, F M Fang, Y S Lin, Y R Yao, F Tong
… nonlinear model (MVDLNM), Lorenz curve and Gini index. Our health impact assessments indicate that PM exposure has resulted in significant increases in TB burden. Specifically, approximately $1,202 million (95% CI: 801-1,573 million), $486 million (95% CI: 398-572 million), and …
Mugwagwa T, Abubakar I, White PJ
…burden settings. Methods An integrated transmission-dynamic health economic model is used to assess the cost-effectiveness of using WGS to replace culture-based drug-sensitivity testing, versus using molecular testing versus combined use of WGS and molecular testing, for routine …
Alberto Perelló, José Sánchez-Cesteros, Patricia Barroso, David Relimpio, Víctor Lizana, et al.
… richness and arid climate, with implications for livestock health, economic sustainability of cattle farms, and reduction of zoonotic risk in rural areas.
Julie Huynh, Chishala Chabala, Suvasini Sharma, Louise Choo, Varinder Singh, et al.
…c biomarkers, in-depth neurodevelopmental outcomes, MRI and health economics. **ETHICS AND DISSEMINATION:** Local ethics committees at all participating study sites and respective regulators approved the SURE protocol. Ethics approval was also obtained from UCL, UK (14935/001). …
Nezenega ZS, Perimal-Lewis L, Maeder AJ
Background Tuberculosis (TB) is a major global public health problem and one of the leading causes of death among infectious diseases. Although TB can be cured with first-line antibiotics treatment of 6 months regimen, non-adherence to the treatment remains the main challenge for…
Sakallioglu IT, Barletta RG, Dussault PH, Powers R
…erial diseases, continues to cause serious global economic, health, and social problems. Current TB treatments are lengthy, expensive, and routinely ineffective against emerging drug resistant strains. Thus, there is an urgent need for the identification and development of novel …
Patel LN, Gurumurthy M, Bronson G, Sanders K, Rusen ID
…, community engagement, regulatory and ethics requirements, health economics, and other (respondent designated) about which a practical guide would be useful to improve future trial implementation. For each aspect of trial implementation selected, respondents were asked to report…
Mgcini Moyo, Thobani Ntshiqa, Yohhei Hamada, Andrew Copas, Issa Sabi, et al.
…ks of diagnosis at the time of recruitment by study team at health facilities in selected districts or regions. Each TB index patient and their contact(s) will be randomised into either universal TB testing or standard TB screening arms. Household and community contacts listed by…
Prakash Ghosh, Shaheda Anwar, Martin Siegel, Julius Boniface Okuni, Manfred Weidmann, et al.
… with cervical lymphadenitis will be enrolled from tertiary healthcare facilities in Bangladesh and Uganda. Each participant will be subjected to laboratory investigations including microscopy, real-time PCR, cytology, culture and Xpert MTB/RIF Ultra with the tissue sample follow…
Kassem AF, Sabt A, Korycka-Machala M, Shaldam MA, Kawka M, et al.
Tuberculosis is a global serious problem that imposes major health, economic and social challenges worldwide. The search for new antitubercular drugs is extremely important which could be achieved via inhibition of different druggable targets. Mycobacterium tuberculosis enoyl acy…
Hualin Jiang, Rui Li, Tianhua Zhang, Qinghu Wang, Haini Liu, et al.
…d impact on reducing TB incidence. We aimed to evaluate the health impact and cost-effectiveness of expanding TPT to key community-level population METHODS: We developed a dynamic transmission model incorporating the effect of TPT and seasonal variations in TB incidence. The mode…
Navarro CE, Benjumea-Bedoya D, Estupinan-Bohorquez AF, Florez ID
… tuberculosis (TB) patients in the context of the Colombian healthcare system. Design Health economic evaluation. Decision tree over a horizon of Setting From the perspective of the Colombian healthcare system, the direct healthcare costs related to tests were considered, and dia…
Mullerpattan JB, Udwadia ZZ, Banka RA, Ganatra SR, Udwadia ZF
Background Private healthcare is choice of point of care for 70% of Indians. Multidrug resistant tuberculosis (MDR-TB) treatment is costly and involves duration as long as 2 years. Aim To estimate costs to patients undergoing treatment for MDR-TB. Methods A health-economics quest…
Saifur Rehman, Shakeeb Ullah, Kholik Kholik, Muhammad Munawaroh, Akhmad Sukri, et al.
…ead, variables that increase the risk, importance to public health, economic impact, treatment, and methods of controlling bovine brucellosis. Bovine tuberculosis primarily affects cattle although it can also affect other animals. Bovine brucellosis is a global illness that occur…
Nabeemeeah F, Sabet N, Otwombe K, Hlongwane K, Mlambo LM, et al.
…without respiratory illness at enrolment, attending primary healthcare clinics to initiate or reinitiate ART, was prospectively enrolled and followed. HospCAP and StART participants (totalling 2950 participants) were followed for at least 1 year and assessed for CAP episodes, hos…
Charl Bezuidenhout, Lawrence Long, Brooke Nichols, Gesine Meyer-Rath, Matthew P Fox, et al.
…cts of people with confirmed TB residing in South Africa. A health economic assessment was executed to estimate and compare the cost and cost-effectiveness of different in-home POC testing strategies against centralized sputum testing (standard of care) from a provider's perspect…
Vessière A, Font H, Gabillard D, Adonis-Koffi L, Borand L, et al.
…l-cause mortality 12 weeks after inclusion. Qualitative and health economic evaluations are embedded in the trial. Discussion In addition to testing the main hypothesis that molecular detection and early treatment will reduce TB mortality in children, the strength of such pragmat…
Halliday A, Jain P, Hoang L, Parker R, Tolosa-Wright M, et al.
…ures, measured each of the new technologies and performed a health economic analysis in which the best-performing tests were evaluated for cost-effectiveness. The diagnostic accuracy of the transcriptomic tests ranged from an AUC of 0.81 to 0.84 for detecting all TB in our cohort…
Mafirakureva N, Mukherjee S, de Souza M, Kelly-Cirino C, Songane MJP, et al.
…ent and TPT provision at HIV clinics. To add to the limited health-economic evidence on interventions to improve ATT and TPT in children, we evaluated the cost-effectiveness of the CaP-TB intervention. Methods and findings We analysed clinic-level pre/post data to quantify the im…
Park HY, Kwon JW, Kim HL, Kwon SH, Nam JH, et al.
… group) to treat newly diagnosed MDR-TB patients. Methods A health economic analysis over lifetime horizon (20 years) from the perspective of the healthcare system in Korea was conducted. We developed a combined simulation model of a decision tree model (initial two years) and tw…
To KW, Zhang R, Lee SS
… studies for TBST have been conducted without exploring the health economics for preventing development of LTBI into active TB. Unlike IGRA, no clinical studies have addressed the correlation of TBST results (magnitude of induration) with the likelihood of development of active T…
Yang P, Song Y, Xia X, Zhang AM
Tuberculosis (TB) is a worldwide health, economic, and social burden, especially in developing countries. Drug-resistant TB is the most serious type of this burden. Thus, it is necessary to screen drug-resistant mutations by using a simple and rapid detection method. A total of 3…
Chatterjee S, Das P, Vassall A
…to curb the spread of coronavirus infection had significant health and economic impacts on the Indian economy. There is limited empirical evidence on how COVID-19 restrictive measures may impact the economic welfare of specific groups of patients, e.g., tuberculosis patients. We …
Cuenca-Lara P, Blay-Benach M, Cervera Z, Melgarejo C, Moraleda J, et al.
…ium tuberculosis complex (MTBC) organisms that pose a great health and economic challenge for the caprine industry in some European and developing countries. It is also a zoonotic disease posing a risk for public health. The control programs of the disease are based on a test-and…
Samsudin EZ, Yasin SM, Ruslan NH, Abdullah NN, Noor AFA, et al.
…virus outbreaks include increased morbidity, mortality, and health costs. This had then led to indirect impacts including social impacts such as employment crises and reduced workforce size as well as economic impacts such as demand shock, supply chain disruptions, increased supp…