Showing 126–150 of 200 documents
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Verma H, Nagar S, Vohra S, Pandey S, Lal D, et al.
Mycobacterium tuberculosis is a known human pathogen that causes the airborne infectious disease tuberculosis (TB). Every year TB infects millions of people worldwide. The emergence of multi-drug resistant (MDR), extensively drug resistant (XDR) and totally drug resistant (TDR) M…
Rizvi SMS, Tarafder S, Anwar S, Perdigão J, Johora FT, et al.
Bangladesh is among the high burden countries for tuberculosis (TB) and multidrug resistant TB (MDR-TB). As the genetic diversity and distinct phylogeographic distribution of Mycobacterium tuberculosis are responsible for regional differences in drug resistance, this cross sectio…
van der Galiën R, Boveneind-Vrubleuskaya NV, Peloquin C, Skrahina A, Touw DJ, et al.
Background and objective Multidrug-resistant tuberculosis has much poorer treatment outcomes compared with drug-susceptible tuberculosis because second-line drugs for treating multidrug resistant tuberculosis are less effective and are frequently associated with side effects. Opt…
Vonnahme LA, Shaw KM, Gulati RK, Hollberg MR, Posey DL, et al.
…ergo a mandatory overseas medical examination that includes tuberculosis screening; this exam is not routinely required for temporary visitors applying for non-immigrant visas (NIV) to visit, work, or study in the United States. US health departments and foreign ministries of hea…
José-María García-García, Teresa Rodrigo-Sanz, José-Antonio Gullón-Blanco, Xavier Casas García, Joan-Pau Millet, et al.
… was to analyse the characteristics of rifampicin-resistant tuberculosis patients in Spain. **METHODS:** This was an ambispective observational study of a multicentre cohort of patients diagnosed between January 2019 and July 2023 in most Autonomous Communities (retrospective pe…
Zabaleta A, Llerena C
Introducción. La tuberculosis extremadamente resistente a los medicamentos (TB-XDR) es el resultado de deficiencias en la administración del tratamiento y en la prevención de la transmisión de la enfermedad; además, es un reto para los programas nacionales de control de la tuberc…
Loukman M, Olivier B, Vincent B, Rachid D, Cyril F, et al.
Background Tuberculosis is the first fatal infectious agent in the world with 1.2 million annual deaths for 10 million cases. Little is known about the epidemiology of tuberculosis and its resistance in Reunion Island, which is at the heart of migratory flows from highly endemic …
Shamsa Kanwal, Ani Haider, Abdul Majeed Akhtar
…ated with loss to follow-up and death during drug-resistant tuberculosis treatment. **METHODS:** The retrospective study was conducted in Punjab, Pakistan, and comprised data from January 1, 2020, to December 31, 2022, of extensively drug resistant tuberculosis patients enrolled…
Heitor Levy Ferreira Praça, Juliana Cavalcanti Figueiredo, Natalia Santana Paiva, Jefferson Pereira Caldas Dos Santos, Paulo Victor de Sousa Viana, et al.
**UNLABELLED:** Drug-resistant tuberculosis remains a major challenge to tuberculosis control in Brazil and worldwide. **OBJECTIVE:** To identify factors associated with unfavorable treatment outcomes and to analyze the occurrence of high-risk spatial clusters at an intra-urban …
Pauline Howell, Jonathan Stillo, Anja Reuter, Tendai Nkomo, Carole D Mitnick, et al.
Drug-resistant tuberculosis is entering a new and dangerous phase. Bedaquiline and other newer drugs have transformed drug-resistant tuberculosis treatment, yet resistance to these agents is now being reported across high-burden settings. In some regions, baseline bedaquiline res…
Abdullahi M, Adeniji SE, Arthur DE, Haruna A
Background Tuberculosis (TB) remains a serious global health challenge that is caused by Mycobacterium tuberculosis and has killed numerous people. This necessitated the urgent need for the hunt and development of more potent drugs against the fast-emerging extensively drug-resis…
Ding C, Wang S, Shangguan Y, Feng X, Guo W, et al.
Purpose Tuberculosis remains a major public health problem globally, especially in undeveloped countries. This study aimed to evaluate and review the long-term epidemic trends of tuberculosis in China. Methods Data were extracted from the Global Health Data Exchange. Metrics (pre…
Annelies Van Rie, Emilyn Costa Conceição, Felex Ndebele, Felicia Wells, Astrid Paulse, et al.
**BACKGROUND:** All patients with rifampicin-resistant tuberculosis should receive a short course of effective treatment. We aimed to evaluate the effectiveness of whole genome sequencing (WGS)-guided treatment in shortening duration of treatment for rifampicin-resistant tubercul…
Molnar TF
…r understanding present concepts and debates on surgery for tuberculosis, but it also contributes to the further developments in operative treatment of lung cancer. Both diseases have been the leading cause of death in their respective ages. History of tuberculosis follows the cl…
Amelework Firomsa Wakuma
…ous illness with a high morbidity and death rate worldwide, tuberculosis (TB) is more prevalent in low- and middle-income nations. Although there are a number of diagnostic techniques, the most only address tuberculosis in the lung and ignore drug-resistant strains (MDR-TB, XDR-T…
Patil K, Bagade S, Bonde S, Sharma S, Saraogi G
Tuberculosis is a highly contagious disease spread by Mycobacterium tuberculosis. It is responsible for highest numbers of death and soon will surpass the deaths caused by HIV. The pandemic disease causes, estimated 10.4 million new infections, among which 5.9 million were men, 3…
Supriya Mallick, Manish Shankar, Satyadeo Choubey, Arshad Ejazi, Rakesh Kumar, et al.
**BACKGROUND:** Multidrug-resistant tuberculosis continues to be a major threat to mankind and is a major social and economic burden to society. Line probe assay (LPA) is a method for detecting Mycobacterium tuberculosis (MTb) in combination with resistance to rifampicin and ison…
Dokladda K, Billamas P, Jaitrong S, Suwanakitti N, Phornsiricharoenphant W, et al.
…id (PAS) was first reported by Lehmann in 1946 and used for tuberculosis treatment. However, due to its adverse effects, it is now used only as a second line anti-tuberculosis drug for treatment of multidrug resistant or extensively drug resistant M. tuberculosis. The structure o…
Abreu R, Giri P, Quinn F
Tuberculosis (TB) has been a transmittable human disease for many thousands of years, and M. tuberculosis is again the number one cause of death worldwide due to a single infectious agent. The intense 6- to 10-month process of multi-drug treatment, combined with the adverse side …
Habibnia S, Karami-Zarandi M, Zaker S, Ghalavand Z, Doustdar F, et al.
…ence of multidrug resistance and extensively drug-resistant tuberculosis is a serious public health crisis. Using rapid and inexpensive molecular methods such as HRM assay in the detection of second-line drugs resistance in M. tuberculosis would be helpful in the treatment and co…
Sundaram K, Vajravelu LK, Velayutham R, Mohan U
…s a genetic element that is highly present in Mycobacterium tuberculosis (MTB), the causative agent of tuberculosis. The toxin-antitoxin system comprises toxin protein and antitoxin protein or non-encoded RNA interacting with each other and inhibiting toxin activity. M. Tuberculo…
Zeynali Kelishomi F, Khanjani S, Fardsanei F, Saghi Sarabi H, Nikkhahi F, et al.
Tuberculosis (TB) caused by Mycobacterium tuberculosis (M. tuberculosis) is a highly infectious disease and worldwide health problem. Based on the WHO TB report, 9 million active TB cases are emerging, leading to 2 million deaths each year. The recent emergence of multidrug-resis…
Puri MM, Kumar A, Aneja P, Gupta R, Kumar L, et al.
…a, hypomagnesaemia, and hypocalcaemia have been reported in tuberculosis patients who have been treated with capreomycin.1-3 Capreomycin is recommended in the treatment of M. tuberculosis isolates resistant to kanamycin at baseline in multi drug resistant tuberculosis patients (M…
Conradie F, Bagdasaryan TR, Borisov S, Howell P, Mikiashvili L, et al.
…reported to have 90% efficacy against highly drug-resistant tuberculosis, but the incidence of adverse events with 1200 mg of linezolid daily has been high. The appropriate dose of linezolid and duration of treatment with this agent to minimize toxic effects while maintaining eff…
Cohen KA, Stott KE, Munsamy V, Manson AL, Earl AM, et al.
In 2019, the WHO tuberculosis (TB) treatment guidelines were updated to recommend only limited use of streptomycin, in favor of newer agents or amikacin as the preferred aminoglycoside for drug-resistant Mycobacterium tuberculosis However, the emergence of resistance to newer dru…