Showing 126–150 of 200 documents
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Jialin Cao, Hui Gan, Jian-Hui Wu, Yue Yuan, Fei Ye
Multiple cases of extrapulmonary tuberculosis (TB) combined with pulmonary TB are commonly encountered in clinical practice. Nasopharyngeal TB is often ignored because of its hidden location and nonspecific manifestations. A correlation between cervical lymph node and nasopharyng…
Tandirogang N, Mappalotteng WU, Raharjo EN, Paramitai S, Bulan DE, et al.
Background Extrapulmonary Tubercolosis (EPTB) is an infectious disease that affects tissue outside the lungs. EPTB patients cannot be source of infection, therefore the findings in the community indicate that there are still active pulmonary TB patients acting as a source of infe…
Alexander W Kay, Maia Madison, Katie Scandrett, Tara Ness, Pauline Amuge, et al.
…ated 1.3 million children (aged 0-14 years) became ill with tuberculosis, and 166,000 children (aged 0-15 years) died from the disease. Xpert MTB/RIF Ultra (Xpert Ultra) is a molecular World Health Organization (WHO)-recommended rapid diagnostic test that detects Mycobacterium tu…
Kay AW, Ness T, Verkuijl SE, Viney K, Brands A, et al.
… one million children and young adolescents become ill with tuberculosis, and around 226,000 of those children die. Xpert MTB/RIF Ultra (Xpert Ultra) is a molecular World Health Organization (WHO)-recommended rapid diagnostic test that simultaneously detects Mycobacterium tubercu…
Zhang J, Wang MG, Xiang X, He JQ
Background Severe tuberculosis constitutes a significant menace to human safety and well-being, with a considerable mortality rate. The severity of tuberculosis can be impacted by genetic variations in host genes, particularly single nucleotide polymorphisms (SNPs). Methods A cas…
Huang Z, LaCourse SM, Kay AW, Stern J, Escudero JN, et al.
Background Tuberculosis remains a leading cause of global mortality, especially for adults and children living with HIV (CLHIV) underdiagnosed by sputum-based assays. Non-sputum-based assays are needed to improve tuberculosis diagnosis and tuberculosis treatment monitoring. Our a…
Bjerrum S, Schiller I, Dendukuri N, Kohli M, Nathavitharana RR, et al.
…y the World Health Organization (WHO) to help detect active tuberculosis in HIV-positive people with severe HIV disease. This review update asks the question, "does new evidence justify the use of LF-LAM in a broader group of people?", and is part of the WHO process for updating …
Martinez L, Cords O, Liu Q, Acuna-Villaorduna C, Bonnet M, et al.
…egarding the effectiveness of BCG vaccination in preventing tuberculosis and death, particularly among older children and adults. We therefore aimed to investigate the age-specific impact of infant BCG vaccination on tuberculosis (pulmonary and extrapulmonary) development and mor…
Keragala BSDP, Herath HMMTB, Janapriya GHDC, Vanitha S, Balendran T, et al.
…d Leprosy is one of the oldest mycobacterial infections and tuberculosis is the most common mycobacterial infection with a higher degree of infectivity than leprosy. Although both diseases are prevalent in clusters in developing countries, simultaneous occurrence of them in an in…
Leeberk Raja Inbaraj, Vignes Anand Srinivasalu, Mukesh Kumar Sathya Narayanan, Adhin Bhaskar, Jefferson Daniel, et al.
…n tests, such as loop-mediated isothermal amplification for tuberculosis (TB-LAMP), are among the molecular WHO-recommended rapid diagnostics and can provide results within a few hours, even in resource-limited settings. We aimed to synthesise evidence on the accuracy of these te…
Kang W, Yu J, Du J, Yang S, Chen H, et al.
Tuberculosis (TB) remains a serious global public health problem in the present. TB also affects other sites (extrapulmonary tuberculosis, EPTB), and accounts for a significant proportion of tuberculosis cases worldwide. In order to comprehensively understand epidemiology of EBTB…
Zaidi S, Errami A, Belkhou I, Elkhaldi M, Ailal F, et al.
…n Morocco has made remarkable progress in the fight against tuberculosis, but the Covid-19 pandemic has affected tuberculosis control worldwide, with notable fluctuations in tuberculosis epidemiology during and after the pandemic. Aim To describe the impact of the Covid-19 pandem…
Olbrich L, Franckling-Smith Z, Larsson L, Sabi I, Ntinginya NE, et al.
…ground Despite causing high mortality worldwide, paediatric tuberculosis is often undiagnosed. We aimed to investigate optimal testing strategies for microbiological confirmation of tuberculosis in children younger than 15 years, including the yield in high-risk subgroups (eg, ch…
Muhammed H, Jain A, Pattanaik SS, Chatterjee R, Naveen R, et al.
Introduction There is paucity of data on tuberculosis in Indian patients with systemic lupus erythematosus (SLE). We retrospectively studied clinical features and outcome of tuberculosis in SLE. Methods Medical records of patients who developed tuberculosis simultaneous or after …
Hoang LT, Jain P, Pillay TD, Tolosa-Wright M, Niazi U, et al.
Background Blood transcriptomic signatures for diagnosis of tuberculosis have shown promise in case-control studies, but none have been prospectively designed or validated in adults presenting with the full clinical spectrum of suspected tuberculosis, including extrapulmonary tub…
Pant P, Joshi A, Adhikari YR, Rijal Y, Ghimire S, et al.
Background Tuberculosis is a common respiratory disease imposing significant health burden. Directly observed treatment short course strategy ensures patient compliance in tuberculosis treatment. The aim of this study was to assess pattern of tuberculosis, trend and outcome of pa…
Limpin ET, Lopez MPJ, Maglangit SACA, Torres JJR, Onglao MAS, et al.
Background The Philippines ranks 10th in tuberculosis prevalence worldwide. Aside from pulmonary tuberculosis, GI tuberculosis remains an important cause of morbidity and mortality, particularly in endemic areas. Objective This study aimed to describe the clinicopathologic profil…
Siddharth Sekhar Sethy, Gagan Deep, P V Sudhakar, Tarun Goyal, Pankaj Kandwal, et al.
…cases of extrapulmonary TB. The incidence of osteoarticular tuberculosis is one of the lowest in extrapulmonary tuberculosis, probably only next to cutaneous tuberculosis in non-HIV patients. Considering the low incidence of primary osteoarticular tuberculosis without pulmonary t…
Harya SA, Nhungo CJ, Lori JM, Mitamo AA, Mkony CA, et al.
Introduction and importance Tuberculosis is prevalent in African countries especially in sub-Saharan Africa where HIV/AIDS is common. While Testicular tuberculosis is uncommon in the young as well as the elderly, pulmonary tuberculosis is commonly observed in these populations. H…
Touihmi S, Rkain I
Introduction Tuberculosis is a chronic bacterial infection caused by the Mycobacterium tuberculosis . Extrapulmonary tuberculosis (EPTB) accounts for about 20% of cases in immunocompetent patients and 50% of cases in HIV-positive individuals (7). Except for the cervical lymph nod…
Khan MK, Islam MN, Ferdous J, Alam MM
Tuberculosis (TB) is a progressive granulomatous infectious disease caused by the gram positive, acid fast bacilli classified under the genus Mycobacterium. Tuberculosis in human is mostly by Mycobacterium tuberculosis and primarily affects lungs causing pulmonary tuberculosis. I…
Li C, Wang S, Yu H, Wang J, Deng J, et al.
The research of childhood tuberculosis is inadequate in china. The cross-priming amplification (CPA) of specific DNA in clinical samples is increasingly adopted for the diagnosis of childhood tuberculosis. In this study, a multicenter research was performed to investigate the inc…
Ndege R, Ngome O, Bani F, Temba Y, Wilson H, et al.
Background Patients with clinically suspected tuberculosis are often treated empirically, as diagnosis - especially of extrapulmonary tuberculosis - remains challenging. This leads to an overtreatment of tuberculosis and to underdiagnosis of possible differential diagnoses. Metho…
Ismail Ouhammou, Hinde Hami, Arabi Rida, Mezouara Mounia, Ouassima Erefai, et al.
**INTRODUCTION:** pleural tuberculosis, the second most common extrapulmonary manifestation after lymph node involvement, poses a considerable diagnostic and therapeutic challenge. This study examines the epidemiological, clinical, biological, and therapeutic features of pleural …
Hammami F, Koubaa M, Ben Ayed H, Rekik K, Ben Jemaa M, et al.
Introduction Tuberculosis affects commonly the lungs, but any other organs can be affected as well. Urogenital tuberculosis is usually misdiagnosed. In this perspective, we aimed to give an update on the epidemiological, clinical and evolutionary features of urogenital tuberculos…