Showing 101–125 of 200 documents
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Charutha Retnakumar, Palanivel Chinnakali, Balaji Bharadwaj, Karikalan Nagarajan, Sonali Sarkar
We aimed to compare the proportion of tuberculosis infection among social contacts of male tuberculosis Index case with and without alcohol use in the Puducherry district. A cross-sectional study using ego-centric approach was conducted between November 2023 and May 2024. A total…
Lanping Zhang, Wenjun He, Xiufen Wang, Xue Li, Jinghui Chang, et al.
**BACKGROUND:** Inadequate health knowledge of tuberculosis patients is one of the causes of poor adherence among tuberculosis patients in China's tuberculosis control. In this study, we will develop and validate the effectiveness of a large language model (LLM) to improve the he…
Moonan PK, Nair SA, Agarwal R, Chadha VK, Dewan PK, et al.
The End TB Strategy envisions a world free of tuberculosis-zero deaths, disease and suffering due to tuberculosis by 2035. This requires reducing the global tuberculosis incidence from >1250 cases per million people to <100 cases per million people within the next two decades. Ex…
Emily McNair, Shahanara Valawalkar, Samyra R Cox, Abhay Kadam, Gayatri Lele, et al.
**BACKGROUND:** Post-tuberculosis lung disease is a well-recognized sequela of pulmonary tuberculosis (PTB). Extra-pulmonary tuberculosis (EPTB) accounts for a quarter of the global tuberculosis burden; yet pulmonary sequelae in people treated for EPTB are unknown. **METHODS:** …
Rakhmawati W, Nilmanat K, Hatthakit U
Objective Children living in tuberculosis households need protection. However, families need to be engaged to prevent tuberculosis transmission to children. This study aimed to analyze the details of "moving from fear to realization," which is one category of a substantive theory…
Cristine Cerva, Fabio Marcelo de Lima, Ana Paula Muterle Varela, Gabriela Merker Breyer, Jerônimo Miguel Vicenzi, et al.
Bovine tuberculosis susceptibility and pathogenesis are influenced by host immunity, which may be modulated by the host microbiota. While intestinal microbiota composition affects pulmonary diseases in humans, its role in bovine tuberculosis remains unclear. This study explores t…
Yanti B, Mulyadi M, Amin M, Harapan H, Mertaniasih NM, et al.
Objective The role of Mycobacterium tuberculosis complex (MTBC) species in tuberculosis (TB) infection in human is still questioned. The aim of this study was to determine whether M. tuberculosis and M. bovis is associated with apoptosis and necroptosis by measuring the expressio…
Mustafa AS
…potent immunogenic protein secreted by the bacteria causing tuberculosis, i.e., Mycobacterium tuberculosis. Another highly immunogenic culture filtrate protein whose gene is linked to ESAT6/ESXA is known as CFP10/ESXB. Because of their high immunogenicity and specificity to M. tu…
Levillain F, Kim H, Woong Kwon K, Clark S, Cia F, et al.
Tuberculosis still claims more lives than any other pathogen, and a vaccine better than BCG is urgently needed. One of the challenges for novel TB vaccines is to protect against all Mycobacterium tuberculosis lineages, including the most virulent ones, such as the Beijing lineage…
Wu W, Cheng P, Lyu J, Zhang Z, Xu J
… a Tag Array chip for detecting first- and second-line anti tuberculosis drug resistance in pulmonary tuberculosis and compared the analytical performance of the gene chip to that of phenotypic drug susceptibility testing (DST). Methods From November 2011 to April 2016.234 consec…
Micheni LN, Kassaza K, Kinyi H, Ntulume I, Bazira J
Infections with multiple strains of Mycobacterium tuberculosis are now widely recognized as a common occurrence. Identification of patients infected with multiple strains provides both insight into the disease dynamics and the epidemiology of tuberculosis. Analysis of Mycobacteri…
Wan L, Guo Q, Wei JH, Liu HC, Li MC, et al.
Background Drug resistant tuberculosis poses a great challenge for tuberculosis control worldwide. Timely determination of drug resistance and effective individual treatment are essential for blocking the transmission of drug resistant Mycobacterium tuberculosis. We aimed to esta…
Hernández-Bustamante I, Santander-Plantamura Y, Mata-Espinosa D, Reyes-Chaparro A, Bini EI, et al.
…me is considered the precursor of type 2 diabetes mellitus. Tuberculosis is a leading infection that constitutes a global threat remaining a major cause of morbi-mortality in developing countries. People with type 2 diabetes mellitus are more likely to suffer from infection with …
Marcy O, Wobudeya E, Font H, Vessière A, Chabala C, et al.
Background Tuberculosis diagnosis might be delayed or missed in children with severe pneumonia because this diagnosis is usually only considered in cases of prolonged symptoms or antibiotic failure. Systematic tuberculosis detection at hospital admission could increase case detec…
Atahan E, Saribas S, Demirci M, Babalık A, Akkus S, et al.
…expression levels can be used to assess the success of anti-tuberculosis treatment outcomes to detect viable mycobacteria cells. Therefore, we evaluated the levels of 85B mRNA of Mycobacterium tuberculosis strains in patients with pulmonary tuberculosis. Methods Thirty patients w…
Laura Olbrich, Leyla Larsson, Rory Dunbar, Peter J Dodd, Megan Palmer, et al.
…* In 2023, almost 200,000 children under 15 years died from tuberculosis, most without appropriate treatment. Treatment decision algorithms (TDAs), developed to facilitate rapid anti-tuberculosis treatment initiation in children, were recommended by the World Health Organization …
Tenaye L, Mengiste B, Baraki N, Mulu E
…might attribute to high infectious diseases burden, such as tuberculosis. The global importance of diabetes mellitus as a tuberculosis-risk factor is still not a well-established fact. Thus, we conducted this study to determine the prevalence of diabetes mellitus and its associat…
Gautam N, Karki RR, Khanam R
Background Tuberculosis is one of the major infectious diseases and is both complex and serious. It is spread from person to person through the air, causing a public health burden, especially in low- and middle-income countries. This study aims to assess the knowledge on tubercul…
Kimura M, Araoka H, Baba H, Okada C, Murase Y, et al.
Tuberculosis screening was performed for a healthy asymptomatic woman to determine whether she had been infected with active genital tuberculosis via sexual intercourse with her husband who had epididymal tuberculosis. Vaginal swab culture yielded Mycobacterium tuberculosis. Furt…
Kobayashi T, Tsuyuguchi K, Kasai T, Suzuki K
Tuberculosis may be accompanied by various hematological abnormalities during treatment, and occasionally thrombocytopenia is also noted. Most cases of thrombocytopenia in tuberculosis are moderate, and there are few reports about thrombocytopenia with diffuse alveolar hemorrhagi…
Peter Scott, Maysa Elsayedkarar, Edson Marambire, Gertrude Ncube, Tsitsi Apollo, et al.
**BACKGROUND:** Tuberculosis household contacts are at elevated risk of HIV, and systematic screening for tuberculosis is an opportunity for people to know their status. We aimed to assess the coverage and positivity of HIV testing during household systematic screening for tuberc…
Li X, Wang J, Yang Z, Song Q
Objective Early diagnosis of osteoarticular tuberculosis helps improve patients' outcomes, but little is known about the accuracy of noninvasive diagnostic methods. This case-control study aimed to assess the diagnostic value of peripheral blood T-cell spot of tuberculosis assay …
Yu J, Huang W, Zhang G, Xiao R
Tuberculosis is a chronic infectious disease that gradually poses a certain threat to public health and economic growth. Tuberculosis typically affects the lungs, pleura, and lymph nodes and rarely the skin. Cutaneous tuberculosis manifesting as ulcerated lesions is also rare and…
Lawal IO, Mokoala KMG, Mathebula M, Moagi I, Popoola GO, et al.
…rd course of anti-tuberculous treatment (ATT) for pulmonary tuberculosis and are declared cured according to the current standard of care commonly have residual metabolic activity (RMA) in their lungs on fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomogra…
Khan PY, Paracha MS, Grundy C, Saeed S, Dojki M, et al.
Background: Assessment of the effectiveness of tuberculosis control strategies requires the periodic measurement of M. tuberculosis transmission in populations, which is notoriously difficult. One well-established method is to measure the prevalence of infectious pulmonary tuberc…