Showing 101–125 of 200 documents
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Nagar M, Joshi A, Sahu S, Nagar V, Mitra A
Background Musculoskeletal tuberculosis (TB) continues to share the major burden of extrapulmonary TB. This burden up to some extent may be attributed to the implementation gap which is reasonably broadest at the level of the immediate point of care. As an orthopedic physician is…
Selmane S, L'Hadj M
…d at highlighting some demographic and clinical features of tuberculosis (TB) at Leon Bernard TB unit, Algeria. Methods This was a retrospective and descriptive study based on TB data extracted from TB patient records during 2009-2019 at Leon Bernard TB unit. Results Of the total…
Wang MS, Wang JL, Liu XJ
Background In China, the prevalence of tuberculosis (TB) diseases and epidemiological trends in the TB forms among children are still unclear; a retrospective study was conducted aiming to assess it. Methods Between January 2007 and September 2020, 1577 consecutive childhood TB p…
Sun W, Lu Z, Yan L
…s Specimens were tested by mNGS and other routine tests for tuberculosis (TB). The diagnostic accuracy of mNGS was calculated and compared with the final clinical diagnosis. Results The sensitivity of mNGS was found to be significantly higher than the sensitivities of the other r…
Chen S, Wang C, Zou Y, Zong Z, Xue Y, et al.
…ackground Existing diagnostic approaches for paucibacillary tuberculosis (TB) are limited by the low sensitivity of testing methods and difficulty in obtaining suitable samples. Methods An ultrasensitive TB diagnostic strategy was established, integrating efficient and specific T…
Kang W, Liu S, Du J, Tang P, Chen H, et al.
Aims A high proportion of all patients with tuberculosis (TB) present with extrapulmonary TB (EPTB), including concurrent EPTB involving more than one extrapulmonary lesion site. However, previous reports only characterized lesions of single-site EPTB cases. This study aimed to i…
Hoel IM, Sviland L, Syre H, Dyrhol-Riise AM, Skarstein I, et al.
Background Extrapulmonary tuberculosis (EPTB) poses diagnostic challenges due to the paucibacillary nature of the disease. The immunochemistry-based MPT64 antigen detection test (MPT64 test) has shown promising results for diagnosing EPTB in previous studies performed in low-reso…
Kanade SR, Nataraj G, Mehta PR
Background In India, musculoskeletal tuberculosis (TB) accounts for 10%-25% of extrapulmonary TB. Data on drug-resistant skeletal TB are lacking. At present, the diagnosis is based mainly on radiological techniques. Laboratory confirmation of skeletal TB is delayed as 6-8 weeks a…
Oliveira M, Vita-Campos C, Jeunon T
Tuberculosis (TB) is a common condition with increasing incidence worldwide. Cutaneous TB represents a small portion of extrapulmonary TB. Health care professionals must be aware of cutaneous forms of TB to avoid delay in diagnosis and treatment. We present a case of a 59-year-ol…
Eletreby R, Elsharkawy A, Mohamed R, Hamed M, Kamal Ibrahim E, et al.
…droxyvitamin D3 (25(OH)D3) concentrations in extrapulmonary tuberculosis (EPTB) patients and to evaluate the effect of vitamin D3 supplementation on their treatment course. Methods Serum 25(OH)D3concentrations were measured in 47 newly diagnosed EPTB patients and 42 controls. Vit…
Aouraghe H, Benchekroun S, Mahraoui C, ElHafidi N
Multifocal tuberculosis (TB) accounts for up to one-third of all cases of TB and children are at higher risk for extrapulmonary TB than adults. Spinal TB is the regular form of skeletal TB. Spondylodiscitis TB represents 47%-94% of spinal TB. Cervical localization is rare but rem…
Xuan Ying Poh, Fei Kean Loh, Chen Bai, Hai Tarng Chong, Wei Keat Teo, et al.
…te anti-tuberculous treatment (ATT), central nervous system tuberculosis (CNS-TB) still causes permanent neurological deficits and death. To identify prognostic factors, we profiled a prospective cohort of pediatric HIV-negative tuberculous meningitis (TBM) and non-TBM patients. …
Basu Roy R, Thee S, Blázquez-Gamero D, Falcón-Neyra L, Neth O, et al.
…27 healthcare institutions providing care for children with tuberculosis (TB) in nine European countries. Results Of 118 children included, 54 (45.8%) had definite, 38 (32.2%) probable and 26 (22.0%) possible TBM; 39 (33.1%) had TBM grade 1, 68 (57.6%) grade 2 and 11 (9.3%) grade…
Salma Madihi, Achraf Aainouss, Mly Driss Ei Messaoudi, Abdelouaheb Benani
Tuberculosis (TB) is a major health burden, the leading cause of death among people living with HIV, and one of the main causes of death linked to antimicrobial resistance. The World Health Organization (WHO) launched in 2015 the End TB Initiative that aims to reduce TB cases and…
Jackline Anase Nlula, Sembakutti Samita, Etienne Yuh Jam, Bernard Ngowi, Ellen Mitchell, et al.
…ita Region of Tanzania is known as critical focal point for tuberculosis (TB) control due to its persistently high disease burden and unique socio-economic landscape. Despite this, limited research has explored how sociodemographic and clinical factors influence TB presentation (…
Shakoor S, Mir F, Hasan R
Background Children evaluated for tuberculosis (TB) are often diagnosed with miscellaneous conditions that mimic TB. Knowledge of differentials informs policy on service provision through liaison with referral centers offering definitive diagnosis and treatment for common alterna…
Singh J, Dinkar A
Tuberculosis (TB) is known to cause a wide variety of complications and atypical presentations. It usually presents with typical symptoms. Here, we present the unusual case of pulmonary TB with the involvement of lungs, brain, liver, spleen, vertebra, skin, left cervical lymph no…
Yi Hao Wong, Hai Tarng Chong, Ting Huey Hu, Catherine Wei Min Ong
Despite the World Health Organization End TB Strategy, tuberculosis (TB) remains the world's leading infectious cause of death. Conventional antimicrobial therapies are hindered by prolonged treatment durations, poor patient adherence, and drug toxicity. Host-directed therapies (…
Pinsai S
Abstract Background Tuberculosis (TB) and HIV are one of the significant public health problems in Thailand, and an estimated 15,000 individuals have a dual infection. Both HIV and TB each disease speeds up the progression of each other. TB is the leading cause of death in HIV-in…
Camil Mihuta, Adriana Socaci, Patricia Hogea, Emanuela Tudorache, Monica Simina Mihuta, et al.
: Tuberculosis and COVID-19 co-infection poses significant clinical challenges, with pulmonary TB (PTB) and extrapulmonary TB (extraPTB) potentially influencing disease progression and outcomes differently. This study aims to compare the clinical manifestations, inflammatory mark…
Khanal S, Kafle A, Bhandari S, Kayastha P
…n her breast for 2 months, which was diagnosed with mammary tuberculosis on basis of aspiration cytology and successfully treated with antitubercular drugs. Breast abscess of long duration may be tubercular etiology in both developing and developed nations.
Luntsi G, Ugwu AC, Ahmadu MS, Ohagwu CC, Sidi M, et al.
…nfected with acquired immune deficiency syndrome (AIDS) and tuberculosis (TB) coinfection. An extensive literature search was conducted between 1994 and 2021 for original peer-reviewed articles in the English language on ultrasound application in the diagnosis of extrapulmonary T…
Ye Z, Zhu J, Liu C, Lu Q, Wu S, et al.
Background Tuberculosis (TB) is a chronic infectious disease. Bone and joint TB is a common type of extrapulmonary TB and often occurs secondary to TB infection. In this study, we aimed to find the difference in the blood examination results of patients with bone and joint TB and…
Coelho LE, Chazallon C, Laureillard D, Escada R, N'takpe JB, et al.
…therapy (ART) initiation, people with HIV (PWH) treated for tuberculosis (TB) may develop TB-associated immune reconstitution inflammatory syndrome (TB-IRIS). Integrase inhibitors, by providing a faster HIV-RNA decline than efavirenz, might increase the risk for this complication…
Gupta L, Aggarwal R, Naveen R, Lawrence A, Zanwar A, et al.
…ic inflammatory myositis (IIM) with India being endemic for Tuberculosis (TB). We compared and contrasted the prevalence, clinical profile and outcomes of active TB in IIM with systemic lupus erythematosus (SLE). Methods Medical records were reviewed for adults and children with …