Showing 101–125 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Hensel J, McAndrews KM, McGrail DJ, Dowlatshahi DP, LeBleu VS, et al.
The Bacillus Calmette-Guerin (BCG) vaccine provides protection against tuberculosis (TB), and is thought to provide protection against non-TB infectious diseases. BCG vaccination has recently been proposed as a strategy to prevent infection with SARS-CoV-2 (CoV-2) to combat the C…
Asare-Baah M, Séraphin MN, Salmon LAT, Lauzardo M
Mixed infections with genetically distinct Mycobacterium tuberculosis (MTB) strains within a single host have been documented in different settings; however, this phenomenon is rarely considered in the management and care of new and relapse tuberculosis (T.B.) cases. This study a…
Aandahl RZ, Bhatia S, Vaudagnotto N, Street AG, Francis AR, et al.
Molecular epidemiology uses genetic information from bacterial isolates to shed light on the population structure and dynamics of pathogens. Bacterial pathogens can now be studied by whole genome sequencing, but for some well-studied pathogens such as Mycobacterium tuberculosis a…
Reis AC, Reis AC, Ramos B, Pereira AC, Cunha MV
… gain insights into research subtopics within the animal TB epidemiology domain and to highlight territorial inequalities regarding data reporting and research outputs over the years. To deliver such information, peer-reviewed reports of TB studies in livestock were retrieved fro…
Guthrie JL, Marchand-Austin A, Cronin K, Lam K, Pyskir D, et al.
Objectives Compare the molecular epidemiology of tuberculosis (TB) between two large Canadian provinces-Ontario and British Columbia (BC)-to identify genotypic clusters within and across both provinces, allowing for an improved understanding of genotype data and providing context…
Li M, Cai L, Gao Q
…n of asymptomatic TB to transmission in China using genomic epidemiology data from five population-based studies, encompassing 6,387 TB patients and 1,626 genomic-clustered patients. Transmission were classified as originating from either asymptomatic or symptomatic TB by compari…
Domínguez J, Acosta F, Pérez-Lago L, Sambrano D, Batista V, et al.
Systematic molecular/genomic epidemiology studies for tuberculosis surveillance cannot be implemented in many countries. We selected Panama as a model for an alternative strategy. Mycobacterial interspersed repetitive unit-variable-number tandem-repeat (MIRU-VNTR) analysis reveal…
Kruczak K, Augustynowicz-Kopeć E, Kozińska M, Passak-Stańda G, Niżankowska-Mogilnicka E, et al.
Background The transmission of tuberculosis may affect the incidence rate of the disease in Poland. Genetic methods are of assistance in tracing the infection transmission, identifying its sources, determining the risk groups, and focusing on the preventive actions. Objectives Th…
Allen A, Magee R, Devaney R, Ardis T, McNally C, et al.
…rovides the highest resolution data available for molecular epidemiology, producing richer outbreak tracing, insights into phylogeography and epidemic evolutionary history. We illustrate these advantages by focusing on a common single lineage of M. bovis (1.140) from Northern Ire…
Vindenes T, Jordan MR, Tibbs A, Stopka TJ, Johnson D, et al.
…e in Massachusetts, it is necessary to understand the local epidemiology and transmission risks. Methods We used an existing TB case database of Massachusetts TB cases in the time frame from 2012 to 2015, which links de-identified patient demographic information with TB genotypes…
Mtetwa HN, Amoah ID, Kumari S, Bux F, Reddy P
… alternative surveillance methods, such as wastewater-based epidemiology. This studyinvestigated the presence, concentration, and diversity of Mycobacterium tuberculosis complex, the cause of TB, in from six African countries: Ghana, Nigeria, Kenya, Uganda, Cameroon, and South Af…
Yang C, Gao Q
…tize the strategies for TB control. Evidence from molecular epidemiology studies has delineated the recent transmission of Mycobacterium tuberculosis (M. tuberculosis) strains in many settings. However, the transmission patterns of TB in most areas of China are still not clear. S…
Osei Sekyere J, Reta MA, Maningi NE, Fourie PB
…alth problem. However, a systematic review of TB resistance epidemiology in Africa is wanting. Methods A comprehensive systematic search of PubMed, Web of Science and ScienceDirect for English research articles reporting on the molecular epidemiology of Mycobacterium tuberculosis…
Christopher PM, Widysanto A
…e use of GeneXpert MTB/RIF assay to determine the molecular epidemiology of RR-TB in an urban setting of Indonesia. Methods All molecular epidemiological and microbiological databases were retrospectively examined from GeneXpert MTB/RIF assay results in Siloam Hospital Lippo Vill…
Agius PA, Cutts JC, Song P, Rudan I, Rudan D, et al.
An epidemiological transition in the prevalence of peripheral artery disease (PAD) is taking place especially in low- and middle-income countries (LMICs) where an ageing population and adoption of western lifestyles are associated with an increase in PAD. We discuss the limited e…
Shinichiro Hirai, Masaki Nakamura, Satoshi Kawato, Yushi Hachisu, Takashi Kikuchi, et al.
**INTRODUCTION:** While multi-locus variable number tandem repeat analysis (MLVA) as molecular epidemiological analysis has been used to detect Mycobacterium tuberculosis outbreaks, its discriminatory power for identifying strains is limited. Whole-genome sequencing (WGS) offers …
Pereira AC, Pérez de Val B, Cunha MV
…n in Iberia. We highlight the value of intersecting genomic epidemiology with molecular ecology to resolve epidemiological links and show that an EU-official eradication program in goats is utterly needed to control TB in a multi-host scenario.
Meng Li, Long Cai, Qian Gao
…n of asymptomatic TB to transmission in China using genomic epidemiology data from five population-based studies, encompassing 6,387 TB patients and 1,626 genomic-clustered patients. Transmission were classified as originating from either asymptomatic or symptomatic TB by compari…
Kone B, Somboro AM, Holl JL, Baya B, Togo AA, et al.
…uch as the African region. Recent developments in molecular epidemiology tools have significantly improved our understanding of TB transmission patterns and revealed the high genetic diversity of TB isolates across geographical entities in Africa. This study reports the results o…
Weinrick B
Molecular epidemiology studies of tuberculosis have been empowered in recent years by the availability of whole-genome sequencing, which has allowed a new focus on the adaptive significance of drug resistance mutations. Genome sequencing technology remains expensive, however, lim…
Mizukoshi F, Kobayashi N, Kirikae F, Ohta K, Tsuyuguchi K, et al.
…operties of drug-resistant tuberculosis in Japan. Molecular epidemiology provides several clues to inform potential measures to control drug-resistant tuberculosis in Japan.
Al-Jardani A, Al Yaquobi F, Adikaram C, Al Wahaibi A, Al-Balushi L, et al.
…and exploring the geospatial distribution to understand the epidemiology of TB in Oman. Methods Confirmed cases with spoligotyping clusters were randomly selected. WGS of 70 isolates were selected for final analysis. Correlation of epidemiological and geospatial data was conducte…
Alvarez GG, Zwerling AA, Duncan C, Pease C, Van Dyk D, et al.
Background In the last decade, tuberculosis (TB) incidence among Inuit in the Canadian Arctic has been rising. Our aim was to better understand the transmission dynamics of TB in this remote region of Canada using whole-genome sequencing. Methods Isolates from patients who had cu…
Jiao L, Song J, Chen H, Gu D, Liao S, et al.
To date, many studies have been conducted to investigate associations between variants and tuberculosis risk; however, the results have been inconclusive. Here, we systematically provide a summary of the understanding of the genetic architecture of tuberculosis susceptibility. We…
Zheng H, Xiao J, Yang H, Li F, Guo Y, et al.
Data on epidemiology trends of paediatric tuberculosis (TB) are limited in China. So, we investigated the clinical and epidemiological profiles in diagnosed TB disease and TB infection patients at Beijing Children's Hospital. Of 3 193 patients, 51.05% had pulmonary TB (PTB) and 1…