Showing 76–100 of 200 documents
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Araújo RM, Montenegro RA, Peixoto ADS, Silva LLS, da Costa RMPJ, et al.
Background The diagnosis of extrapulmonary tuberculosis (EPTB) shows numerous difficulties because of non-specific symptomatology and low sensitivity of conventional methods. Loop-mediated isothermal amplification (LAMP) is a fast and low-cost technique, which can amplify under i…
Sevilla-Fuentes S, Mendoza-Vargas LÁ, Araiza-Rodríguez JF, Berthaúd-González B, Falfán-Valencia R, et al.
…l cavity was requested, confirming the diagnosis of lingual tuberculosis, an extremely rare disease, occurring in less than 1% of extrapulmonary cases. MRI of the cervical spine showed a crush fracture of the C6 and C7 bodies associated with spondylitis of probably infectious eti…
Lan Y, Chen L, Zhang H
Extrapulmonary tuberculosis (EPTB) accounted for 14% of 6.4 million cases of TB that were reported to WHO in 2017, and genitourinary TB (GUTB) is the second most common type of EPTB. The most common site of GUTB is the kidneys and testicular TB is relatively rare. The case of one…
Atherton RR, Cresswell FV, Ellis J, Skipper C, Tadeo KK, et al.
…ion recommended the Xpert ® MTB/RIF Ultra assay (Ultra) for tuberculosis (TB) diagnosis. Ultra offers improved analytical sensitivity when compared with the initial Xpert ® MTB/RIF (Xpert) assay for the detection of Mycobacterium tuberculosis. Ultra is therefore likely to be of p…
Venus Marie R Rojas, Michaela Zwyer, Selim Bouaouina, Daniela Brites, Sonia Borrell, et al.
The Mycobacterium tuberculosis complex (MTBC) phylogenetic lineages 1-4 (L1-L4) are the main causes of human tuberculosis (TB). Until now, most of the focus in the TB field has been on MTBC L2 and L4, as these two lineages are geographically widespread and have been repeatedly as…
Fang Y, Zhou Q, Li L, Zhou Y, Sha W
…udy aimed to investigate the epidemiology of extrapulmonary tuberculosis (EPTB) and analyse the epidemiological characteristics of EPTB patients with or without pulmonary tuberculosis (PTB). EPTB cases admitted in our hospital from January 2015 to December 2020 were included. Uni…
Varghese B, Enani M, Alrajhi A, Al Johani S, Albarak A, et al.
…ckground Growing evidences suggested that the Mycobacterium tuberculosis complex (MTBC) lineages can determine the clinical outcome of pulmonary and extra-pulmonary tuberculosis. However, limited data only available revealing such association of bacterial genotypes and clinical p…
van Heerden JK, van Zyl A, Schaaf HS, Frigati LJ, Goussard P, et al.
Background Tuberculosis (TB) and childhood cancers have overlapping presentations and malignancies may be misdiagnosed as TB in high TB-burden settings. Methods This retrospective study investigated the diagnosis of TB in children with cancer registered in the Tygerberg Hospital …
Ule Belotti NC, Madela NK, Tonelli Nardi SM, Mariano DC, de Souza NG, et al.
Background The Xpert Mycobacterium tuberculosis Rifampicin (MTB-RIF) is a technological innovation that presents precision and speed in the diagnosis of tuberculosis (TB). The study aimed to evaluate the performance of Xpert MTB/RIF in the TB diagnosis and compare its results wit…
Niu T, He F, Yang J, Ma C, Xu J, et al.
Background Pulmonary tuberculosis (PTB) complicated with extrapulmonary tuberculosis (EPTB) infection can aggravate the disease, but there have been few reports. Methods Retrospective analysis was used to collect the clinical data of PTB patients with pathogen positive in a teach…
Wenting J, Yuyan M, Qingfeng S, Yao Z, Yumeng Y, et al.
Background and purpose abdominal tuberculosis (TB) is a common form of extrapulmonary TB but it is still a diagnostic dilemma in clinical practice. This study aimed to highlight the clinical features and diagnostic approaches for abdominal TB. Methods seventy cases of diagnosed a…
Hoel IM, Syre H, Skarstein I, Mustafa T
The diagnosis of extrapulmonary tuberculosis (EPTB) is often challenging due to paucibacillary nature of the disease. Xpert MTB/RIF Ultra (Ultra) has been developed to improve detection of Mycobacterium tuberculosis complex (MTC) in paucibacillary specimens. The objective of the …
Jain S, Bajgai P, Kaur S, Dogra M, Sharma A, et al.
… To describe the prevalence and clinical findings of ocular tuberculosis (TB) in Human immunodeficiency virus (HIV) and systemic TB co-infected patients. Methods : In this prospective, observational, non-comparative case series, we included HIV and systemic TB co-infected patient…
Ozbakir H, Guner Ozenen G, Ergun D, Kacar P, Gulderen M, et al.
Background Tuberculosis (TB) infection is transmitted by sharing the same airway with people with active TB. Children are often not considered the source of TB bacilli, and index case investigation is carried out after diagnosis. Here, we describe the impact of the presence of a …
Uddin MKM, Ather MF, Rahman A, Nasrin R, Rahman SMM, et al.
Tuberculosis (TB) remains one of the leading causes of death and Bangladesh ranks 7th among the highest TB burden countries. Though molecular epidemiological data for pulmonary TB (PTB) have previously been described in Bangladesh, data on the molecular characterization and clini…
Weber SF, Saravu K, Heller T, Kadavigere R, Vishwanath S, et al.
Diagnosing extrapulmonary tuberculosis (EPTB) is challenging. Point-of-care ultrasound (POCUS) for human immunodeficiency virus (HIV)-associated EPTB is applied in sub-Saharan Africa. This study aimed at evaluating the applicability of POCUS for diagnosing EPTB in HIV-positive an…
Maitre T, Bonnet M, Calmy A, Raberahona M, Rakotoarivelo RA, et al.
…s meningitis (TBM) is the most lethal and disabling form of tuberculosis (TB), particularly in sub-Saharan Africa. Current anti-TB treatment is poorly effective since TBM mortality reaches 40% in HIV-negative patients and up to 70% in HIV-co-infected patients. To reduce TBM-induc…
Dahiya B, Khan A, Khan A, Mor P, Kamra E, et al.
…e small circulating vesicles released from urine samples of tuberculosis (TB) patients, contain a pool of biomarkers. We recently detected Mycobacterium tuberculosis lipoarabinomannan (LAM) and CFP-10 (Rv3874) biomarkers from the urinary EVs of pulmonary TB (PTB) and extrapulmona…
Vielgut I, Putzl L, Thomüller I, Igrec J, Brcic I, et al.
…ead of the disease and secondary deformity, musculoskeletal tuberculosis (TB) remains a challenge in terms of early diagnosis and treatment. This study gives an overview on TB trends in Austria (pulmonary and extrapulmonary TB) (A) and analyses a retrospective series of musculosk…
Qian X, Nguyen DT, Lyu J, Albers AE, Bi X, et al.
…ognized as risk factors for dissemination of extrapulmonary tuberculosis (EPTB). However, there are few population-based studies investigating the association between the primary sites of tuberculosis (TB) infection and mortality during TB treatment. De-identified population-base…
Abstract Background Extrapulmonary tuberculosis (EPTB) is quite prevalent in India, ranging from 8.3% and 13.1%. Diagnosis of EPTB is often challenging as it resembles other granulomatous conditions pathologically. TB culture remains the gold standard for definitive diagnosis, bu…
Ishan Shevate, Sarthak Walia, Kishankumar Mahida, Rahul Salunkhe, Rishabh Aggarwal
**INTRODUCTION:** Tuberculosis (TB) remains a significant health issue in India, with approximately 30-40% incidence. While only 18% of TB cases are extrapulmonary, shoulder TB, particularly Caries sicca, is extremely rare. Caries sicca is characterized by severe pain, restricted…
Mohd Redhuan AM, Abu Bakar MY, Mohd Shahriman AF, Nur Syafiqa A, Noor Faizah A, et al.
Introduction Tuberculosis (TB) remains a highly prevalent disease in Malaysia. Early identification using cost-effective methods such as chest radiography can reduce the health burden of a TB epidemic. However, normal chest radiographic findings are common. This study aimed to ev…
S A Susilo, A B Harsono, G N A Winarno, S Salima, K I Mantilidewi
An uncommon form of extrapulmonary tuberculosis is abdominal tuberculosis (TB). Due to its vague symptoms, abdominal TB remains difficult to diagnose. We report three cases of peritoneal TB with abdominal enlargement in Bandung, Indonesia, which were initially misdiagnosed as ova…
Sharma JB, Dharmendra S, Rapaka G, Singh UB, Kriplani A, et al.
Background and objective Female genital tuberculosis (FGTB) is an important type of extrapulmonary tuberculosis (TB) associated with morbidity especially infertility in developing countries. Laparoscopy may be difficult and hazardous in FGTB. The aim of the study was to observe t…