Showing 51–75 of 200 documents
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Igwaran A, Edoamodu CE
Tuberculosis is one of the oldest known diseases and the leading communicable cause of deaths worldwide. Although several studies have been carried out on tuberculosis, no research has examined the publication trends in this area. Hence, this study aimed to fill the gap by conduc…
Sinha M, Rani R, Bagga P
Objectives To analyse correlation of past history of tuberculosis with present state of infertility with respect to HSG and diagnostic findings, with a view to assess the frequency of genital tuberculosis in infertile women, its clinical presentation and association with infertil…
Mishra H, Reeve BWP, Palmer Z, Caldwell J, Dolby T, et al.
Background Xpert MTB/RIF Ultra (Ultra) is a new test for tuberculosis undergoing global roll-out. We assessed the performance of Ultra compared with Xpert MTB/RIF (Xpert) in an HIV-endemic setting where previous tuberculosis is frequent and current test performance is suboptimal.…
Luo D, Wang L, Liu H, Li L, Liao Y, et al.
Tuberculosis caused by Mycobacterium tuberculosis (M. tuberculosis) is the leading cause of death among infectious diseases in the worldwide. Lack of more sensitive and effective diagnostic reagents has increased the awareness of rapid diagnosis for tuberculosis. In this study, T…
Jin J, Geng H, Li Y, Wang M, Yang S, et al.
…ness and its influencing factors of patients with pulmonary tuberculosis on preferential policies for tuberculosis prevention and treatment in Shandong, China. A total of 858 patients with pulmonary tuberculosis between January 1, 2018 and September 30, 2019 were surveyed with qu…
Jayasooriya S, Dimambro-Denson F, Beecroft C, Balen J, Awokola B, et al.
…und Many patients in sub-Saharan Africa whom a diagnosis of tuberculosis is considered are subsequently not diagnosed with tuberculosis. The proportion of patients this represents, and their alternative diagnoses, have not previously been systematically reviewed. Methods We searc…
AlHamawi R, Khader Y, Abaza H, Satyanarayana S, Wilson N, et al.
Background Tuberculosis knowledge, practices, and perceived stigma and discrimination among patients with tuberculosis are key factors for the management of the disease. Objectives The objectives of the study were to assess knowledge, practices, perceived stigma and discriminatio…
Risco D, Martínez R, Bravo M, Fernández Llario P, Cerrato R, et al.
…ground Wild boar is an important reservoir of Mycobacterium tuberculosis variant bovis , the main causative agent of bovine tuberculosis (bTB). A proportion of tuberculosis (TB)-affected wild boars shed M tuberculosis by nasal route, favouring the maintenance of bTB in a multihos…
Mei YM, Zhang WY, Sun JY, Jiang HQ, Shi Y, et al.
Objectives Cutaneous tuberculosis with various manifestations can be divided into several clinical types according to the host's immune status and infective route. However, the etiological factors of this disease remain unclear. The objective of this study is to investigate the p…
Ketema W, Woubishet K, Tesfaye S, Gutema S, Taye K, et al.
Background Tuberculosis is commonly detected late or not at all in HIV-positive people. Rapid and sensitive molecular tests like Gene X-pert have recently become available to replace or supplement existing conventional tests for detecting tuberculosis, and the World Health Organi…
Sadovska D, Nodieva A, Pole I, Vīksna A, Ķimsis J, et al.
Background Current tuberculosis treatment regimens primarily rely on phenotypic drug susceptibility testing and rapid molecular assays. Although whole-genome sequencing (WGS) offers a promising alternative, disagreements between phenotypic and molecular testing methods remain. In…
Yu J, Liu M, Mijiti X, Liu H, Wang Q, et al.
…on between vitamin D receptor ( VDR ) gene polymorphism and tuberculosis susceptibility, as well as the potential interaction of host genetic factors with the heterogeneity of Mycobacterium tuberculosis in the population from Xinjiang, China. Methods From January 2019 to January …
Liu M, Wang Q, Liu H, Yin C, Mijiti X, et al.
…lymorphisms in MBL2 may contribute to the susceptibility to tuberculosis. The aim of the present study was to determine the associations of the polymorphisms of five loci (rs1800450, rs1800451, rs7096206, rs7095891, and rs11003125) in the MBL2 gene with susceptibility to tubercul…
Sari NIP, Mertaniasih NM, Soedarsono, Maruyama F
…nd accurate diagnosis are very important in managing active tuberculosis because they provide an advantage in preventing further disease transmission. In accordance with the recommendation of the World Health Organization, the Indonesian Tuberculosis Control Program uses the acid…
Richard G White, Gavin J Churchyard, Katherine C Horton, Andrew Fiore-Gartland, Marcel A Behr, et al.
Current licensure trials of new vaccines to prevent tuberculosis disease use bacteriologically confirmed symptomatic tuberculosis disease as the primary endpoint. Globally, the incidence of symptomatic tuberculosis disease is low, making licensure trials large, long, and expensiv…
Li QH, Zhang Y, Zhao MM, Gu Y, Hu Y, et al.
…eous application and testing method to detect Mycobacterium tuberculosis rRNA (SAT-TB) with the endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) biopsy specimens to differentiate sputum-negative tuberculosis from sarcoidosis. In the first part, we vali…
Rajamanickam A, Ann Daniel E, Dasan B, Thiruvengadam K, Chandrasekaran P, et al.
Background The progression from Mycobacterium tuberculosis infection to active tuberculosis disease varies among individuals, and identifying biomarkers to predict progression is crucial for guiding interventions. In this study, we aimed to determine plasma immune biomarker profi…
Seifert M, Vargas E, Ruiz-Valdepeñas Montiel V, Wang J, Rodwell TC, et al.
Outside of the ongoing COVID-19 pandemic, tuberculosis is the leading cause of infectious disease mortality globally. Currently, there is no commercially available point-of-care diagnostic that is rapid, inexpensive, and highly sensitive for the diagnosis of active tuberculosis d…
Ehlers LP, Bianchi MV, Argenta FF, Lopes BC, Taunde PA, et al.
Tuberculosis is a common zooanthroponosis in humans with a high incidence in Brazil, but it may also affect non-human primates (NHPs), of which Old World primates are most commonly involved. Nonetheless, its occurrence in New World primates is unknown, and therefore, this study a…
Poudyal IP, Khanal P, Mishra SR, Malla M, Poudel P, et al.
…e co-morbidity of cardiometabolic diseases in patients with Tuberculosis adds a significant burden in current health systems in developing countries including Nepal. The main objective of this study was to explore cardiometabolic risk factors among patients with Tuberculosis. Met…
Kanabalan RD, Lee LJ, Lee TY, Chong PP, Hassan L, et al.
Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria encompassing nine members of closely related species that causes tuberculosis in animals and humans. Among the nine members, Mycobacterium tuberculosis (M. tuberculosis) remains the main causative agent f…
Burke RM, Nliwasa M, Dodd PJ, Feasey HRA, Khundi M, et al.
Background Tuberculosis case-finding interventions are critical to meeting World Health Organization End TB strategy goals. We investigated the impact of community-wide tuberculosis active case finding (ACF) alongside scale-up of human immunodeficiency virus (HIV) testing and car…
Berihun YA, Nguse TM, Gebretekle GB
Background Prevalence of tuberculosis in vulnerable groups such as prisoners is usually high, and the problem is worsened by poor treatment outcomes. In spite of this, there is limited information regarding tuberculosis in prisons of Ethiopia. Hence, this study was aimed to asses…
Gezahegn LK, Argaw E, Assefa B, Geberesilassie A, Hagazi M
…amide has proved to be highly effective in the treatment of tuberculosis (TB). However, the most common adverse effect of this regimen leading to interruption of therapy is hepatotoxicity. There is a paucity of evidence in Tigray region on anti-tuberculosis drug-induced hepatitis…
Tornheim JA, Madugundu AK, Paradkar M, Fukutani KF, Queiroz ATL, et al.
…kground Gene expression profiling is emerging as a tool for tuberculosis diagnosis and treatment response monitoring, but limited data specific to Indian children and incident tuberculosis infection (TBI) exist. Methods Sixteen pediatric Indian tuberculosis cases were age- and se…