Showing 51–75 of 200 documents
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Behzadifar M, Martini M, Behzadifar M, Bragazzi NL
Tuberculosis is a serious respiratory infectious disease, caused by Mycobacterium tuberculosis bacteria. It has always represented a permanent, serious public health challenge over the course of human history, because of its severe epidemiological, clinical and societal implicati…
Abayneh M, Teressa M
…istently deciding its current extent and chance elements of tuberculosis (TB) in all levels of clinical settings contributes to the anticipation and control exertion of the disease. In Ethiopia, updated information is still needed at every healthcare level and in different risk g…
Kassa M, Desta K, Ambachew R, Gebreyohannes Z, Gebreyohanns A, et al.
Background Mycobacterium tuberculosis (M. tuberculosis) remains one of the most significant causes of death and a major public health problem in the community. As a result, the aim of this study was to determine magnitude of Mycobacterium tuberculosis, its drug resistance, and as…
Xiaoqin Xiong, Fangfang Zhong
…sess the global, regional, and national burden of pulmonary tuberculosis (TB), including drug-susceptible (DS-TB) and multidrug-resistant TB (MDR-TB), among children and adolescents from 1990 to 2021, and to project trends to 2045. **METHODS:** Data were extracted from the Globa…
Selim A, Elhaig MM, Taha SA, Nasr EA
Tuberculosis (TB) is an endemic disease in animals and humans in Egypt. This study aims to investigate the antimycobacterial activity of silver nanoparticles(AgNPs) by determining the minimal inhibitory concentration (MIC) of AgNPs, using the microplate Alamar blue assay. The AgN…
Asnake Simieneh, Rahel Dereje, Tadesse Misganaw, Gossa Fetene Abebe
Multidrug-resistant tuberculosis (MDR-TB) is increasingly recognized as a global public health challenge. Continuous monitoring of the prevalence of MDR-TB and its associated factors is crucial for the effective control and management of this disease. While alarming rates of MDR-…
Oyedeji GJ, Adeyemo C, Dissou A, Abiodun T, Alli OAT, et al.
Background The development of multidrug-resistant tuberculosis (MDR-TB) poses a considerable threat to tuberculosis control programmes in Nigeria. There is an increase in the prevalence of MDR-TB worldwide both among new tuberculosis cases as well as previously-treated ones. Ther…
Vilchèze C, Kim J, Jacobs WR Jr
The treatment of drug-susceptible tuberculosis (TB) is long and cumbersome. Mismanagement of TB treatment can lead to the emergence of drug resistance in patients, so shortening the treatment duration could significantly improve TB chemotherapy and prevent the development of drug…
Elduma AH, Holakouie-Naieni K, Almasi-Hashiani A, Rahimi Foroushani A, Mustafa Hamdan Ali H, et al.
…ble robust method to estimate the causal effect of previous tuberculosis treatment history on the occurrence of multidrug-resistant tuberculosis (MDR-TB). TMLE is a method to estimate the marginal statistical parameters in case-control study design. The aim of this study was to e…
Hameed S, Mahmood N, Chaudhry MN, Ahmad SR, Rahman MA
…alence of drug resistance it is necessary to diagnose TB in tuberculosis sputum suspect patients instead of TB-cultured samples which required a long time of culturing. Comparison of the results of drug resistant bacterial genes in both tuberculosis suspect sputum and multi-drug …
Somphavong S, Berland JL, Gauthier M, Vu TT, Nguyen QH, et al.
Background In Lao People's Democratic Republic (PDR), tuberculosis (TB) prevalence was estimated at 540/100,000 in 2011. Nevertheless, little is known about the genetic characteristics and anti-TB drug resistance of the Mycobacterium tuberculosis population. The main objective of…
…tion of the first United Nations (UN) high-level meeting on tuberculosis (TB) calls countries to diagnose and treat 40 million people with TB globally between 2018 and 2022. Traditionally, in most countries, TB diagnosis has been performed using sputum-smear microscopy, a method …
Bangarwa M, Dhingra D, Mittal M, Saigal K, Ghosh A
…world with almost 27 lakh cases reported in 2019. Pediatric tuberculosis in India accounts for almost 31% of global TB burden. Despite such high mortality and morbidity in children, diagnosis of pulmonary TB in children still remains very challenging. Material and methods This cr…
Esteves LS, Dalla Costa ER, Vasconcellos SEG, Vargas A, Ferreira Junior SLM, et al.
Tuberculosis (TB) remains a major public health problem in the world and Brazil is among the countries with the highest incidence and prevalence rates, and Rio Grande do Sul, a Brazilian state, occupy a prominent position. Multidrug-resistant Mycobacterium tuberculosis (MDR-TB) f…
Ulasi A, Nwachukwu N, Onyeagba R, Umeham S, Amadi A
…rmined the prevalence of rifampicin resistance in pulmonary tuberculosis patients in Enugu Nigeria. Methods A prospective hospital-based study involving 1300 presumptive multidrug-resistant tuberculosis patients was conducted in Enugu between April 2017 and 31st March, 2019.Parti…
Zainabadi K, Walsh KF, Vilbrun SC, Mathurin LD, Lee MH, et al.
Standard methods for enumerating Mycobacterium tuberculosis in patient sputum can miss large populations of viable M. tuberculosis cells that are unable to grow either on solid medium or in liquid medium unless the medium has been extensively diluted. Because these bacteria can b…
de Almeida IN, Vasconcellos SEG, de Assis Figueredo LJ, Dantas NGT, Augusto CJ, et al.
Background In recent decades, Mycobacterium tuberculosis with the RD Rio genotype, frequently isolated from tuberculosis patients in Rio de Janeiro, has become part of the Latin American - Mediterranean (LAM) family and has been associated with multidrug-resistant tuberculosis (M…
J Aliyev
In recent years, the epidemiological situation of tuberculosis in the world has remained tense. One of the main reasons for the epidemiological tension is the rapid increase in resistance to anti-tuberculosis drugs. The status and frequency of resistance among different categorie…
Aliyev J
In recent years, the epidemiological situation of tuberculosis in the world has remained tense. One of the main reasons for the epidemiological tension is the rapid increase in resistance to anti-tuberculosis drugs. The status and frequency of resistance among different categorie…
Yang C, Gao Q
Tuberculosis (TB) has remained an ongoing concern in China. The national scale-up of the Directly Observed Treatment, Short Course (DOTS) program has accelerated the fight against TB in China. Nevertheless, many challenges still remain, including the spread of drug-resistant stra…
Iradukunda A, Ndayishimiye GP, Sinarinzi D, Odjidja EN, Ntakaburimvo N, et al.
…e World Health Organization efforts to expand access to the tuberculosis treatment, multidrug resistant tuberculosis (MDR-TB) remains a major threat. MDR-TB represents a challenge for clinicians and staff operating in national tuberculosis (TB) programmes/centres. In sub-Saharan …
Abaate TJ, Alali AA
…owing global public health concern, and multidrug-resistant Tuberculosis is responsible for roughly one-quarter of all antimicrobial-resistant infection-related deaths worldwide. GeneXpert is a rapid, automated molecular test that detects multi-drug-resistant Tuberculosis using R…
Tilahun M, Shimelis E, Wogayehu T, Assefa G, Wondimagegn G, et al.
…ulti-drug resistance is a major challenge in the control of tuberculosis. Despite newer modalities for diagnosis and treatment, people are still suffering from this disease. Understanding the common gene mutations conferring rifampicin and isoniazid resistance is crucial for the …
Korablioviene J, Mauricas M, Caplinskas S, Zagrebneviene G, Korabliov P
Despite considerable efforts and quite early initiated anti-tuberculosis (TB) actions, Lithuania still remains one of the European Union (EU) countries with the highest tuberculosis rates, especially multidrug-resistant (MDR) TB. According to the European Centre for Disease Preve…
Bahizi G, Majwala RK, Kisaka S, Nyombi A, Musisi K, et al.
Background Drug-resistant tuberculosis (DR-TB), including rifampicin-resistant tuberculosis (RR-TB) and multidrug-resistant tuberculosis (MDR-TB, or RR-TB with additional isoniazid resistance), presents challenges to TB control. In Uganda, the GeneXpert test provides point-of-car…