Showing 51–75 of 200 documents
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Capocci SJ, Sewell J, Smith C, Cropley I, Bhagani S, et al.
… studies to justify this in contemporary high resource, low TB/HIV incidence settings. We sought to assess the uptake, yield and cost-effectiveness of testing for latent and active TB. Methods Adults attending an ambulatory HIV clinic in London, UK were prospectively recruited by…
Jinhong He, Xiangxi He, Xiaoxin Xie, Yanhua Fu, Xingxing Luo, et al.
… conducted in Guiyang Public Health Treatment Center. Of 46 TB/HIV co-infected patients received DTG + 3TC or DTG/3TC, a total of 42 patients were finally enrolled in the study. The outcomes of interest were successful TB treatment, viral load (VL) suppression, and …
Seid A, Girma Y, Abebe A, Dereb E, Kassa M, et al.
…llenges global TB control and prevention efforts, where the TB/HIV co-infection epidemic makes the situation much worse. The aim of the study was to determine the determinant factors associated with patterns of MDR-TB among pulmonary TB patients in the Northwest Amhara, Ethiopia.…
Hayibor KM, Bandoh DA, Asante-Poku A, Kenu E
…ical characteristics were extracted on TB-only-infected and TB/HIV-coinfected patients. The chi-squared test and binary and multiple logistic regression models were used to assess factors associated with adverse treatment outcome. Results Out of the 758 patient records analyzed, …
Hoa NB, Nhung NV
…rbidity and mortality globally. We conducted an analysis of TB/HIV surveillance data to describe the trends in HIV testing coverage and HIV positivity rate among TB patients in Viet Nam, 2011-2017. Main text This was a descriptive study based on review and analysis of surveillanc…
Endeshaw Habtamu Wolelaw, Endalk Getasew Hiruy, Asiya Mohammed Abdu, Kebadnew Mulatu Mihretie
**BACKGROUND:** In patients who have tuberculosis and the human immunodeficiency virus, Tuberculosis is the most prevalent opportunistic illness and the main cause of death. However, little is currently, the time to death and its predictors are known, particularly among individua…
Pean P, Madec Y, Nerrienet E, Borand L, Laureillard D, et al.
IRIS is a common complication in HIV-infected patients treated for tuberculosis (TB) and cART. Our aim was to evaluate NK cell reconstitution in HIV-infected patients with TB-IRIS compared to those without IRIS. 147 HIV-infected patients with TB from the CAMELIA trial were enroll…
Theresa Musa Hassab, Audrey Hamachila, Aubrey Chichonyi Kalungia, Norman Nyazema, Moses Mukosha, et al.
Tuberculosis (TB) and HIV co-infection pose significant challenges in resource-limited settings, contributing to multi-drug-resistant TB when treatment fails. This study aimed to identify determinants of TB treatment outcomes among HIV/TB co-infected patients in Lusaka, Zambia.A …
Konyana SPP, Teixeira NF, Pirjol L, Thwala B, Nkoyane W, et al.
Introduction Cutaneous immune-mediated adverse drug reactions are more prevalent in people with human immunodeficiency virus (PWH). Severe cutaneous adverse drug reactions (SCAR) are a life-threatening subset of cutaneous adverse drug reactions (CADRs) and a significant public he…
Lungu P, Mushota K, Njelesani E, Sukwa T, Lakhi S, et al.
Background Mycobacterium tuberculosis (TB) remains a disease of global health concern and a leading cause of mortality arising from an infectious agent. Protective immunity to TB remains unclear. Suppressor of cytokine signaling-3 (SOCS3) and signal transduction and activator of …
Lwin N, Boyle M, Davis JS
Corticosteroids are the mainstay of therapy for immune reconstitution inflammatory syndrome (IRIS). However, little is known about how to treat IRIS unresponsive to steroids. We report a patient with HIV-TB coinfection who was unresponsive to first prednisolone and then inflixima…
Tesfaye B, Alebel A, Gebrie A, Zegeye A, Tesema C, et al.
Background Tuberculosis and HIV/AIDS are the major public health problems in many parts of the world particularly in resource limited countries like Ethiopia. Although studies have been conducted on the prevalence and associated factors of TB / HIV co-infection in Ethiopia, there…
Sharan R, Bucşan AN, Ganatra S, Paiardini M, Mohan M, et al.
HIV co-infection is the most critical risk factor for the reactivation of latent tuberculosis (TB) infection (LTBI). While CD4 + T cell depletion has been considered the major cause of HIV-induced reactivation of LTBI, recent work in macaques co-infected with Mycobacterium tuberc…
Saavedra Cervera B, López MG, Chiner-Oms Á, García AM, Cancino-Muñoz I, et al.
Genomic studies of the Mycobacterium tuberculosis complex (MTBC) might shed light on the dynamics of its transmission, especially in high-burden settings, where recent outbreaks are embedded in the complex natural history of the disease. To this end, we conducted a 1 year prospec…
Bionghi N, Daftary A, Maharaj B, Msibi Z, Amico KR, et al.
…e-containing TB regimens. Methods Eligible patients were DR-TB/HIV co-infected adults hospitalized for the initiation of Bedaquiline-containing treatment regimens in KwaZulu-Natal, South Africa. A one-way crossover design was used to evaluate levels of adherence and patient accep…
Modongo C, Wang Q, Dima M, Matsiri O, Kgwaadira B, et al.
Background Dolutegravir (DTG) has recently been recommended as a preferred first-line regimen for the treatment of new and treatment-experienced HIV-infected patients. However, potential drug interactions between DTG and rifampicin remain a clinical and public health concern. Met…
LaCourse SM, Seko E, Wood R, Bundi W, Ouma GS, et al.
Objective We evaluated diagnostic performance of oral swab analysis (OSA) for tuberculosis (TB) in a high HIV/TB burden setting in Kenya. Methods In this cross-sectional study, buccal swabs and sputum were collected from 100 participants with suspected TB in outpatient clinics in…
Gengiah S, Connolly C, Yende-Zuma N, Barker PM, Nunn AJ, et al.
Background A quality improvement (QI) collaborative approach to enhancing integrated HIV-Tuberculosis (TB) services may be effective in scaling up and improving the quality of service delivery. Little is known of the role of organizational contextual factors (OCFs) in influencing…
Wang DM, Li QF, Zhu M, Xu YH, Liao Y
…extrapulmonary tuberculosis/human immunodeficiency virus (EPTB/HIV) co-infection patients, especially the resistance profile of culture-confirmed EPTB. The purpose of our study was to analyse the clinical characteristics, common sites and drug resistance profile of culture-confir…
Maji D, Agarwal U, Kumar L, V V, Sharma A
The risk of death in HIV-TB coinfected individuals is far greater than in HIV-only patients. It is critical to provide timely and appropriate therapy in HIV-TB coinfected patients in order to reduce morbidity and mortality. The purpose of this study was to evaluate the clinical p…
Mishkin K, Alaei K, Alikeyeva E, Paynter C, Aringazina A, et al.
Objectives Drug-resistant tuberculosis (TB) poses a serious threat to public health in Kazakhstan. This paper presents findings related to TB treatment outcome and drug resistance status among people co-infected with human immunodeficiency virus (HIV) and TB in Kazakhstan. Method…
Fielies ML, Walker IS
Aneurysmal dilatation secondary to HIV vasculitis is well described being more common in patients under 45 years of age with advanced stage HIV infection (CD4 < 200 cells/µl). Tuberculous meningitis is far more common than previously anticipated with centres in Cape Town publishi…
Muhie NS
Background: Tuberculosis increases human immunodeficiency virus replication and accelerates human immunodeficiency virus progression in both tuberculosis and human immunodeficiency virus coinfected patients. The objective of this study was to determine the incidence rate, surviva…
Mchunu NN, Mwambi HG, Rizopoulos D, Reddy T, Yende-Zuma N
Background The association structure linking the longitudinal and survival sub-models is of fundamental importance in the joint modeling framework and the choice of this structure should be made based on the clinical background of the study. However, this information may not alwa…
Torpey K, Agyei-Nkansah A, Ogyiri L, Forson A, Lartey M, et al.
Tuberculosis (TB) and HIV are strongly linked. There is a 19 times increased risk of developing active TB in people living with HIV than in HIV-negative people with Sub-Saharan Africa being the hardest hit region. According to the WHO, 1.3 million people died from TB, and an addi…