Showing 51–75 of 200 documents
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Sotskiy PO, Sotskaya OL, Hayrapetyan HS, Sarkisian TF, Yeghiazaryan AR, et al.
…us, FMF and colchicine may potentially affect fertility and pregnancy in patients with FMF. The aims of the study are to evaluate the causes of infertility and pregnancy outcome in FMF patients and to compare them with 2 groups: non-FMF patients with peritoneal female genital tub…
Silvia S Chiang, Jonathon R Campbell, Daniele Maria Pelissari, Márcia C Bellotti de Oliveira, Anna Cristina C Carvalho, et al.
…rculosis (TB) annually. Little is known about the impact of pregnancy on TB outcomes. **METHODS:** This study used surveillance data from Brazil's Ministry of Health. We included women aged 11-49 years newly diagnosed with drug-susceptible TB disease between 2016 and 2022, treat…
Nyashadzaishe Mafirakureva, Anna Cartledge, Isobella Bradshaw, Adrie Bekker, Nicole Salazar-Austin, et al.
…, perinatal, and infant health risks of tuberculosis during pregnancy, global estimates of incidence remain scarce. Existing estimates are outdated, and do not include the postpartum period, HIV co-infection, age, or specific changes in risk, limiting our understanding of the tru…
Jennifer A Hughes, Flynn McMorrow, Kristina M Brooks, Mauricio Pinilla, Lee Fairlie, et al.
…re no published data on clofazimine pharmacokinetics during pregnancy, and safety data are limited. We present data from pregnant and postpartum women receiving clofazimine for treatment of rifampicin-resistant tuberculosis (RR-TB). **METHODS:** IMPAACT P1026s was an observation…
Victoria Male, Christine E Jones
…o the newborn, so an alternative strategy is vaccination in pregnancy. This approach has been successfully used to protect newborns against tetanus and pertussis, and vaccines that are primarily offered to protect the mother during pregnancy, such as influenza and COVID-19 vaccin…
Van Schalkwyk M, Bekker A, Decloedt E, Wang J, Theron GB, et al.
Physiological changes during pregnancy may alter the pharmacokinetics (PK) of antituberculosis drugs. The International Maternal Pediatric Adolescent AIDS Clinical Trials Network P1026s was a multicenter, phase IV, observational, prospective PK and safety study of antiretroviral …
Marije Van Schalkwyk, Adrie Bekker, Eric Decloedt, Jiajia Wang, Gerhard B Theron, et al.
…etics (PK) of antituberculosis drugs may be altered by both pregnancy-induced physiological changes and drug interactions in individuals living with HIV who develop tuberculosis. Within the multicenter International Maternal Pediatric Adolescent AIDS Clinical Trials Network P1026…
Birku M, Desalegn G, Kassa G, Tegbaru B, Howe R, et al.
…infection and this suppression could further be enhanced by pregnancy. However, the effect of pregnancy on Mycobacterium tuberculosis (M. tuberculosis)-specific immune response during HIV/latent TB co-infection is not well understood. Here we investigated the changes in M. tuberc…
Hazenberg P, Navaratnam K, Busuulwa P, Waitt C
…bstantial anatomical and physiological changes occur during pregnancy and labor, which impact on drug absorption, distribution, metabolism, and elimination. Reduced maternal concentrations may have a clinically important impact on the efficacy of anti-infectives for mother, fetus…
Jones AJ, Mathad JS, Dooley KE, Eke AC
…rcular (anti-TB) agents and antiretroviral therapy (ART) in pregnancy. Recent findings This review discusses the currently available evidence on the use of anti-TB agents in pregnant PLWH on ART. Pharmacokinetic and safety studies of anti-TB agents during pregnancy and postpartum…
Garay-Aguilar NV, Reynoso-Rosales LR, Llamo-Vilcherrez AP, Toro-Huamanchumo CJ
…10 causes of death worldwide. The significance of TB during pregnancy lies in its symptoms, which can be mistaken for physiological changes associated with pregnancy. This confusion can lead to maternal-perinatal complications. Objective To evaluate the association between pulmon…
Chu Y, Chen Y, Yao W, Wang L, Zhang B, et al.
…lity, and whether LTBI would affect the ovarian reserve and pregnancy outcome of infertile women undergoing intrauterine insemination (IUI) is still unknown. A single-center, retrospective, cohort study was designed that included infertile women undergoing IUI at the Department o…
Mendiratta V, Yadav A
Pregnancy with systemic lupus erythematosus (SLE) requires special attention in view of the enhanced risks to the fetus and the aggravation of SLE during pregnancy. Human immunodeficiency virus infection can further complicate the course of pregnancy as well as the outcome. We pr…
Carlsson C, Lönnermark E, Datta S, Evans CA
…ntion or care recommendations for people around the time of pregnancy were absent from some national policy recommendations and varied in others. Objectives To address the apparent gaps and inconsistencies in policy, we aim to design a systematic review and meta-analysis of the o…
Liu K, Zhang X, Ma X, Jia X, Zhao X, et al.
…though female genital tuberculosis may lead to infertility, pregnancy is still possible, especially through in vitro fertilization (IVF). In this eventuality, even latent tuberculosis (TB) infection is prone to reactivate. Because some of the symptoms of TB overlap with those of …
Simpson G, Philip M, Vogel JP, Scoullar MJL, Graham SM, et al.
For women infected with Mycobacterium tuberculosis, pregnancy is associated with an increased risk of developing or worsening TB disease. TB in pregnancy increases the risk of adverse maternal and neonatal outcomes, however the detection of TB in pregnancy is challenging. We aime…
Litao Guo, Xiaoling Wu, Lin Cao
…cribe the clinical characteristics of MPTB after IVF-ET and pregnancy outcomes to provide reference for early diagnosis and treatment. **METHODS:** Clinical data from patients who developed MPTB after IVF-ET from January 2018-December 2021 were retrospectively and statistically …
Ahmadzia HK, Khorrami N, Carter JA, Stone J, Amdur RL
Objective To compare rates of adverse pregnancy outcomes for HIV, tuberculosis, and malaria-infected patients in the United States with those of uninfected patients. Study design A nationally representative sample of 24,149,664 singleton live births were identified using pregnanc…
Cheng M, Yuan T, Liu Y
…us dissemination of Mycobacterium tuberculosis. Spontaneous pregnancy rate of women with TB is low; furthermore, live birth, spontaneous abortion or ectopic pregnancy may be the outcomes even if pregnancy occurs. Case presentation We report a case of a woman with disseminated TB …
Marian Loveday, Jennifer Hughes, Nobuhle Mchunu, Nonhlanhla Yende-Zuma, Kerry Holloway, et al.
…prospective, observational study. Maternal TB treatment and pregnancy outcomes were documented through ongoing record reviews and clinical assessments conducted to describe infant outcomes. Using Poisson regression with robust standard errors, we evaluated factors associated with…
Gai XY, Chi HB, Zeng L, Cao WL, Chen LX, et al.
…(IVF-ET). It was unclear whether untreated PTB would affect pregnancy outcomes after IVF-ET. Method We conducted a retrospective cohort study of 14,254 infertile patients who had received IVF-ET at Peking University Third Hospital in 2017. Prior PTB was defined as the presence of…
Masood U, Venturini N, Nicoletti P, Dellinger A, Kleiner D, et al.
…r Injury Network between 2004 and 2022 and occurring during pregnancy or 6 months postpartum were reviewed and compared with cases of drug-induced liver injury in nonpregnant women of childbearing age. Among 325 individuals of childbearing age in the Drug-Induced Liver Injury Net…
Wei JL, Zhang L, Xu YL, Gan W, Qi M, et al.
…ospective analysis was conducted involving 50 patients with pregnancy who had pulmonary TB and were admitted to the Third People's Hospital of Kunming (China) between 1 January 2017 and 31 December 2021. These patients were divided into an in-vitro fertilisation and embryo transf…
Yoo H, Lee J, Yim JJ, Bärnighausen T, Tanser F, et al.
We investigated whether mortality risk increases with the number of full-term pregnancies in HIV-infected women. Our study is based on data from the ACDIS cohort, collected in rural KwaZulu-Natal, South Africa. Mortality risk for different number of pregnancies in HIV-infected wo…
Abdillah R, Rachmaini F, Fadhilah D, Almahdy A
…berculosis drugs rifampicin and pyrazinamide combination in pregnancy can cause morphological, visceral and skeletal damage. Several studies showed that propolis improves pregnancy outcomes. This study aims to determine the fetal protective effect of propolis in BALB/c mice given…