Showing 1–25 of 200 documents
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Mohau S. Makatsa
… of the treatment is hampered by multidrug resistant TB and HIV infection. There is an urgent need for an effective TB vaccine to prevent ongoing transmission. The development of a new and efficacious TB vaccine will likely be dependent on our understanding of protective immunity…
Elizabeth Corbett, MD, David Dowdy, MD. PhD, Lawrence Moulton, PhD
… algorithms for TB case detection on Tuberculosis (TB)- and HIV-related outcomes; (2) to compare the impact of using the routine screening and GeneXpert algorithms for exclusion of TB prior to initiation of IPT and ART on TB- and HIV-related outcomes; and (3) to assess the relati…
Lusiana R Idrus, Master
…tionale: The co-infection of human immunodeficiency virus (HIV) and tuberculosis (TB) diseases presents further problems to patient's adherence due to high pill burden and adverse effects in the drug combination therapy. This situation is also a risk of the increase of multi-dru…
John C. Mgogwe, Jaffu Otheniel Chilongola
…nt tuberculosis (MDR-TB) with human immunodeficiency virus (HIV) immunologic state which is marked by chemokine and cytokine distortion is indicated by boosting the defense stimulation to a patient. The effect of coexisting infections on the MDR-TB patient with HIV is still not f…
John C. Mgogwe, Balthazar Nyombi, Oliva S. Massay, Hadija Semvua, Jaffu Chilongola
…lti Drug Resistant Tuberculosis TB (MDR-TB) with or without HIV infection, undergoing treatment with second-line Anti TB plus ARV’s or second-line anti TB. Objective To assess the hematological, biochemical and immunological indices of patients with or without HIV-MDR-TB at the K…
Indana Eva Ajmala, Laksmi Wulandari
TB and HIV have a very close relationship since the development of AIDS. Through a significant reduction in cellular immunity, HIV affects the pathogenesis of tuberculosis, thereby increasing the risk of TB in HIV co-infected individuals. In 2006, there were an estimated 9.2 mill…
Anthony Garcia-Prats, MD, Ethel Weld, MD
…imen (OBR) for multidrug-resistant tuberculosis (MDR-TB) in HIV-infected and HIV-uninfected children with MDR-TB. The purpose of this study is to evaluate the pharmacokinetics, safety, and tolerability of the anti-TB drug DLM in combination with OBR for MDR-TB in HIV-infected an…
Frolova Op, T. I. Sharkova, O. V. Butylchenko, Л. П. Северова, A. V. Abramchenko
…e Russian Federation in 2021, human immunodeficiency virus (HIV) infection was more often registered in the general population than in vulnerable groups. AIMS: This study aimed to determine the characteristic patient cohorts with tuberculosis (TB) and HIV coinfection in dynamic e…
Huma Haider
…ica with a population of approximately 15 million. Malaria, HIV and tuberculosis (TB) remain important public health concerns in the country, despite significant progress over the past two decades. Malaria incidence has declined markedly between 2003 and 2019 (by 81% from 2003 to…
Sujit Kumar Bhattacharyya, Pratik Barma, Rajarshi Bhattacharyya
…n increasing association with human immunodeficiency virus (HIV). As multidrug resistant tuberculosis (MDR-TB) is determined by microbiological testing, early detection of MDR -TB by X-Ray chest is highly recommended to help in guiding diagnostic confirmation. The chest x-ray pat…
…s that both multidrug-resistant tuberculosis spread and the HIV epidemic are factors maintaining the high tuberculosis burden worldwide and in the Russian Federation. The main transmission pathway for HIV-infection in the Russian Federation, as well as in other countries of Easte…
Cruz S. Sebastião, João Samulengo, Joana Pauxão, António Mateus, Zinga David, et al.
TB and HIV continue to increase and constitute major public health concerns worldwide, mainly in resource-limited countries, showing that we are not going to end HIV if we do not also end TB. Herein, we investigated the risk factors related to HIV infection among TB patients in L…
Laston Gonah, Talent Maphosa
…e investigated association of MDR-TB treatment outcomes and HIV status in Zimbabwe. The study was a retrospective cohort study of case records from National TB Surveillance System of MDR-TB patients (>16 years) who were culture proven at diagnosis and started treatment between Ja…
Kelly Dooley, MD
…with certain antiretroviral (ARV) medications used to treat HIV. People whose immune systems are weakened by HIV infection are susceptible to TB, so it is important to find treatments for both that can be given in combination. This study will test the safety of combining a new me…
Dyan Kunthi Nugrahaeni, Salma Zaqiya
…y of previous TB treatment and increased co-infection of TB-HIV (Human Immunodeficiency Virus). This study aimed to identify the relationship between history of previous TB treatment and HIV status with MDR-TB. This is a case control study. The sample case was patients with MDR-T…
World Health Organization. Regional Office for Europe
…oordinating meeting of the WHO collaborating centres on TB, HIV, viral hepatitis and STI was held on 7 May 2020. Due to the COVID-19 pandemic, the meeting was conducted virtually, allowing all participants to attend the meeting remotely. The overall objectives of the meeting were…
Dmytro Butov, MD
…n 44% and 32.9% of TB isolates. The first Ukrainian case of HIV was reported in 1987. Today, Ukraine has the highest HIV rate in the Eastern Europe, with increasing proportion of dual infection. For example, in 2002 the prevalence of TB and HIV co-infection was 6.3%, but in 2006 …
Grant Theron, PhD
…hese clinics are representative of many areas where TB (and HIV) are found at high prevalence. If the constraints of working in such areas can be understood and appropriate changes that work made, the investigators believe the outputs and policy changes generated in this study wi…
World Health Organization. Regional Office for Europe
…oordinating meeting of the WHO collaborating centres on TB, HIV, viral hepatitis and STI was held in Copenhagen, Denmark, on 11–12 November 2019, and included presentations and discussions. The overall objectives were to review the current activities of the participating WHO coll…
World Health Organization. Regional Office for Europe
… WHO Technical Officers together in order to strengthen TB, HIV and viral hepatitis laboratory diagnostics, testing and monitoring capacity. The most recent developments in these fields were covered during expert presentations followed by extensive discussions. Panel discussions,…
Sydney Rosen
…o present at the study clinic for TB screening and optional HIV testing, providing a reward to the index patients for participating, and entering index patients whose contacts do present into a lottery to win a prize.The effectiveness of the intervention in screening a high propo…
Bitrus Joshua Barde, Joseph Okopi, Isiyaku Ahmadu
… the global fight for the elimination of Tuberculosis (TB), HIV coinfection with MDR-TB makes TB management even worse. Previous studies have reported poorer outcomes and staggering high mortality rates among persons coinfected with HIV and MDR-TB. This coinfection is said to be …
Marsha Zahrani, Rebekah Juniati Setiabudi, Helmia Hasan, Manik Retno Wahyunitisari
…n transmission and TB treatment failure. In addition to TB, HIV and diabetes mellitus may raise the risk of TB MDR. To determine the TB MDR risk factors, it's critical to understand the prevalence of TB MDR patients with TB, HIV, and diabetes mellitus histories.Methods: This stud…
Bhim Bahadur Subba, N. Rimal, Bikash Shrestha
…TB is considered one of the opportunistic infection among PLHIV. The increasing burden of HIV/TB co-infection among key population cause problem to maintain adherence to ART and DOTS services. The emergence of MDR-TB is one of the greatest challenge to control and management of b…
Fred Monje, Daniel Kadobera, Yakubu Owolabi, Lilian Bulage, Alex Riolexus Ario, et al.
…rs associated with completion of TB treatment at MRRH among HIV-positive and HIV-negative patients. Results: We identified 331 TB case notifications among children <15 years. TB case notification rates declined from 6.6/100,000 in 2013 to 2.2/100,000 in 2017 [odds ratio (OR)=0…