Showing 1–25 of 200 documents
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Bhanu Desai, Rushi N Patel, Yashvi Vijaykumar Dattani, Tamannaben Rameshbhai Ninama, Amay Himanshu Khara, et al.
… TB in children. Paediatric clinical feature is variable in tuberculosis. Many cases of primary TB infection in children are asymptomatic and remain completely unnoticed or accidentally discovered at a later stage. In this study we looked for clinical and radiological presentatio…
Ery Olivianto, Agustin Iskandar, Triyana Dian Dhuha Akmaly, Sarah Zoraya Mirza, Maxie Felix Jahono
Background: Tuberculosis (TB) remains a major global health challenge, particularly among children. Diagnosing pediatric TB is complicated due to nonspecific symptoms and the difficulty of obtaining sputum samples for microbiological confirmation. Immunological tests, such as the…
Amodini Lakshmeswar, Mamta N. Anand, M B Koujalgi
…ackground: In India, an estimated 220,000 children contract tuberculosis (TB) annually, yet the absence of a gold standard test hinders effective diagnosis and reporting of childhood TB. Objective: This study aimed to analyse the clinical profile of childhood tuberculosis, utiliz…
Shrinivasa B. Marinaik, Sriram Selvaraju, R. Srinivasan, Krishnamoorthy, Sunil Kumar Raina, et al.
Background: About one-fifth of the global gap in TB diagnosis was contributed by India which translates to roughly over half a million cases. Meanwhile the National tuberculosis elimination programme has made coordinated efforts to involve public and private health providers in a…
Emad Siddiqui, Tooba Siddiqui, Abdus Salam Khan
Abstract Background Tuberculosis (TB), a preventable airborne infectious disease, early detection is essential to improve health outcomes. Extent of childhood tuberculosis is unknown and is estimated to be around 6% of all incidences. Diagnosis of pediatric tuberculosis is always…
Pınar Etiz, Ali Tanju Altunsu
…xamine the epidemiologic features and treatment outcomes of pediatric pulmonary tuberculosis cases who were registered to the Adana Tuberculosis Dispensaries. Materials and Methods: Fifty-six pediatric patients aged 0-18 years with the diagnosis of pulmonary tuberculosis were exa…
Dhruv Gandhi, Meenakshi Dey, Sonal Patil, Dhruv Mamtora, Ira Shah
Abstract Background The diagnosis of pediatric tuberculosis (TB) remains challenging due to difficulties in specimen collection and the paucibacillary nature of the disease. While Mycobacteria Growth Indicator Tube (MGIT) culture is the gold standard, its long turnaround time lim…
Laura Moretó Planas, MD
Tuberculosis (TB) diagnosis in children is challenging in low and middle-income countries where access to TB culture and X-ray is limited. More than half cases of childhood TB remain undiagnosed every year. A delay in TB diagnosis can lead to an increase in preventable morbidity …
Jyoti Sharma, Sanjeev Chaudhary, Sandesh Guleria, Vipan Garg, Anju Bala
…AAT) positivity in presumptive pulmonary and extrapulmonary tuberculosis (EPTB) in pediatric patients.Materials and methods: It was a descriptive observational study done in pediatric presumptive pulmonary tuberculosis (PTB) and EPTB patients in a tertiary care institute of north…
Daniel Edisha Garba, Uju Marie-Esther Dibua, Chiamaka Ukamaka Oka, Yvonne Ogechukwu Ozoadibe, Friday Attah, et al.
Urogenital tuberculosis (UGTB) is a common extrapulmonary manifestation of TB, but its diagnosis remains challenging due to nonspecific symptoms and limited diagnostic tools. Despite its significant impact on global health, it remains incompletely understood and often overlooked.…
Robert Sinurat
Tuberculosis myelitis usually impacts adult patients and is associated with tuberculous meningitis, miliary tuberculosis, or human immunodeficiency virus infection. Pediatric tuberculosis myelitis cases without any associated diseases have never been reported. The author reported…
N.S. Pravada, А. M. Budritskiy, V.A. Seryogina
Objectives. To assess the peculiarities of diagnosis and clinical course of tuberculosis in children and adolescents. Material and methods. Retrospective analysis of outpatient records of children and adolescents with tuberculosis in Vitebsk region during the period from 2016 to …
Hsin-Ching Kuo, Solomon Chih‐Cheng Chen, Hsin-Kai Lin, Shu-Ti Chia, Joseph-Hang Leung
…(ADA), interferon-gamma release assays (IGRA) confirmed the diagnosis of tuberculosis (TB). By using the optimal cut-off value of 39 IU/L (range: 36–40 IU/L), an elevated ascitic ADA level of 71 IU/L confirmed the diagnosis of TB peritonitis.1Lewinsohn D.M. Leonard M.K. LoBue P.A…
BHARAT BHUSHAN TRIPATHI, DEEPAK KUMAR PATEL, DEVPRIYA SHUKLA, Anurag Jain
Objective: To study the clinical profile and outcome of tuberculosis (TB) in children under 14 years of age. Methods: It is a hospital-based cross-sectional study done in a tertiary referral center in Central India from July 2017 to June 2019. After ethical approval, 80 children …
C. A. Campos Seabra, A. Silva, Raquel Duro, A. Paupério, Vítor Fagundes
…rbidities can present diagnostic challenges. Extrapulmonary tuberculosis, particularly urogenital tuberculosis, is a rare but important cause of persistent genitourinary symptoms. We describe the case of an 83-year-old female with hypertension, diabetes, chronic kidney disease, a…
Işıl Ezel Taşkın Karaçay, Tuğba Erat, Saliha Kanık Yüksek, Pınar Nalçacıoğlu, Rana Beyoğlu, et al.
To the Editors: Orbital tuberculosis (O-TB) is a rare form of extrapulmonary TB that may mimic neoplasms, inflammatory pseudotumors, or abscesses. Diagnosis relies on microbiology, PCR, histopathology and imaging. Despite challenges, outcomes are favorable with timely antitubercu…
Aditya Pawar, Niranjan Sahoo, Pawan Sharma, Nidhi Rathi
…ountries like India where the general dictum is to consider Tuberculosis as one of the differential diagnosis to any condition that is still under evaluation. Parotid Tuberculosis is a very rare entity. There are fewer than 200 cases reported in literature worldwide of Parotid gl…
Muhammad Sidat, Gil Muvale, Mohammad Salgado, Cátia Domingos, Suraia Tane Liasse, et al.
<h3>Background</h3> Tuberculosis (TB) diagnosis is challenging in children, particularly in infants, contributing to high TB-related mortality. Up to 30% of infants with pulmonary TB have concurrent extrapulmonary disease, with findings that can frequently be detected with ultras…
Young Seok Seo, Ji‐Man Kang, Dong Soo Kim, Jong Gyun Ahn
… cartridge-based nucleic acid amplification assay for rapid tuberculosis diagnosis and assessment of antibiotic sensitivity. Although previous evidence supports the use of Xpert for diagnosing extrapulmonary tuberculosis (EPTB) in adults, information regarding the accuracy of Xpe…
Alejandro Rojas Urrea, Daniela Marino, Ana María Rojas-Faura, Mónica Liseth Holguín Barrera, Lorena García Agudelo
Tuberculosis is known as “the great mimicker.” Extrapulmonary tuberculosis accounts for approximately 20% of all cases, with about 10% of these involving the intestines. The ileocecal region is the most common site due to its high density of lymphoid tissue, slowed intestinal tra…
Bineeta Kashyap, Neha Gupta, Pooja Dewan, Puneeta Hyanki, NarendraPal Singh
Objectives Childhood tuberculosis (TB) accounts for 10–20% of all TB cases, with tuberculous meningitis (TBM) being the leading cause of severe morbidity and mortality. Pathophysiology of TBM still remains obscure. Tumor necrosis factor-α (TNF-α) induces fever and activation of h…
Ana Alice Amaral Ibiapina Parente, Rafaela Baroni Aurílio, Clemax Couto Sant’Anna, Maria de Fátima Bazhuni Pombo Sant’Anna, Afrânio Lineu Kriski, et al.
…uction in the value of the detection limit of Mycobacterium tuberculosis(M. tb.) from 116(from Xpert) to 15.6 CFU. The classification of bacillary load is: high, medium, low, and traces. In Brazil, in children(under 10 years) and in extrapulmonary tuberculosis(EPTB), the result o…
Altynai Zhumabekova
…diagnosed with tuberculous meningitis and miliary pulmonary tuberculosis (TB) during her 16th week of pregnancy. The patient presented with symptoms such as vomiting, severe debilitation, lethargy, and loss of appetite. Chest radiography revealed pulmonary TB with a disseminated …
Tran Thi Van Anh, Phan Viet Hai, Do Thien Hai, Trinh Cuong Loi, Phạm Trung Kiên, et al.
Abstract: Objective: Some factors related to the diagnosis of tuberculous meningitis at the National Children's Hospital (2019 - 2024). Subjects and methods: Cross-sectional descriptive study of 50 children from 1 month to 15 years old diagnosed and treated for tuberculous mening…
Kani Dayal Khare, Krishnendu Maiti
Abstract Tuberculosis secondary affects the genitourinary system, has vague symptoms, and is uncommon in children younger than 3–10 years. Renal thimble bladder (TB) damage, including renal failure and decreased bladder capacity, results from a delayed diagnosis. Here, we will di…