Showing 176–200 of 200 documents
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Preeti Preeti, Ameeta Joshi, Madhuparna Dev
Introduction: Tuberculosis is caused by Mycobacterium tuberculosis and remains a leading infectious cause of mortality globally. Linezolid, an oxazolidinone, has strong in vitro evidence of action against drug resistant isolates of M. tuberculosis. It can be administered orally o…
Citra Wulandari, Ziske Maritska
Drug-resistant tuberculosis is a public health concern. TB that is drug-resistant to rifampin and isoniazid is known as MDR-TB, whereas XDR-TB is MDR-TB that is also resistant to second-line medicines, such as fluoroquinolones (levofloxacin, ofloxacin, and moxifloxacin). rifampin…
Michael L. Chen
…nosis of multidrug resistant and extensively drug resistant tuberculosis is a global health priority. Whole genome sequencing of clinical Mycobacterium tuberculosis isolates promises to circumvent the long wait times and limited scope of conventional phenotypic antimicrobial susc…
Duraipandiyan Veeramuthu, Ignacimuthu Savarimuthu, Inshad Ali Khan, Hissah Abdulrahman Alodaini, Ashraf Atef Hatamleh, et al.
Emergence of multidrug resistant strains of Mycobacterium tuberculosis is globally threatening the world and creating problems for the management of tuberculosis (TB). Traditional medicine and plant secondary metabolites are playing an important role in medicine; they are also us…
I. V. Liskina, М. С. Опанасенко, О. V. Теreshkovych, O.O. Melnyk, L. М. Zahaba, et al.
Tuberculosis (TB) remains a global medical problem and is one of the leading causes of death from infectious diseases worldwide. One of the main factors preventing successful control of the infection is the progressive increase in cases of drug-resistant TB. In order to increase …
Seema rani
Antimicrobial resistance (AMR) in Mycobacterium tuberculosis (M. tuberculosis) has emerged as one of the most pressing challenges in global public health. The development of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of tuberculosis (TB) has rendered c…
Akhilesh Kumar Maurya, Nidhi Mishra
Mycobacterium tuberculosis is a bacterial disease that infects and causes tuberculosis (TB) in humans. Millions of people are infected by M. tuberculosis worldwide; so, it is important to have potential drugs against tuberculosis (TB). Mycobacteria have been reported to be multid…
Koku Sisay Tamirat, Gashaw Andargie, Yaregal Animut Babel
Abstract Background: Tuberculosis (TB) generally considered as an ambulatory disease. However, hospitalization remains an important component for isolation and medical stabilization of patients. Hence, this study aimed to identify factors influencing the length of hospital stay d…
Abdul Rashid dayo, Shahzad Memon, Yar Muhammad Tunio, Kashif Ali, Maria Basheer, et al.
… the frequency of HIV infections in patients with pulmonary tuberculosis. Patients and methods: This cross-sectional study, was conducted at the Department of Medicine, Ghulam Muhammad Mehar Medical College, Sukkur, from October 2019 to 2020. All the patients had pulmonary TB of …
Olivera Bojovic, D. Gudelj, S. Lucic, Božidarka Rakočević
…ound: In the conditions of declining rate of drug-resistant tuberculosis and high success rate of treatment of these cases, occurrence of MDR/XDR-TB due to complexity of its treatment remains the main problem in controlling this disease in Montenegro. Methods and materials: Data …
Kavitha Saravu, Madhukar Pai
Drug-resistant tuberculosis (DR-TB) continues to be a global health crisis. In 2017, an estimated 558 000 people had rifampicin-resistant TB (RR-TB), and 82% of them had multidrug-resistant TB (MDR-TB); 3.5% of new TB cases and 18% of previously treated cases had MDR/RR-TB. A qua…
Aynias Seid, Nega Berhane
Tuberculosis (TB) is an infectious chronic human disease caused by Mycobacterium tuberculosis (MTB) bacteria. M. tuberculosis has a great capability of resistance with plentiful natural and acquired mechanisms in their genome that contribute to the spread of highly drug resistanc…
Venugopala KN, Christophe Tratrat, Manormoney Pillay, Sandeep Chandrashekharappa, Al-Attraqchi OHA, et al.
…86 39413Email sandeepc@instem.res.inBackground and Purpose: Tuberculosis has been reported to be the worldwide leading cause of death resulting from a sole infectious agent. The emergence of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis has made the…
Deepali Vp, Shreeya, M. Arjun, Vidya Niranjan
Tuberculosis, a bacterial infection caused by the organism Mycobacterium Tuberculosis, is a widespread disease infecting roughly one-fourth of the world’s population. Although a majority of these cases remain asymptomatic, tuberculosis continues to be the second- most common caus…
Mukesh Masand, Pramod Kumar Sharma, Vishal M. Balaramnavar, Deepti Mathpal
Abstract: The World Health Organization (WHO) considers tuberculosis to be the most dangerous chronic communicable disease in the world, infecting two billion people or one-third of the world’s population. Tuberculosis (TB) caused by Mycobacterium tuberculosis remains a leading c…
…patients with destructive forms of drug-resistant pulmonary tuberculosis remains a difficult problem. The presence of a destruction cavity in the lung reduces the effectiveness of therapy and is a negative prognostic factor. The objective of the study: to search for the optimal t…
N.A. Pavluchenkova, A.V. Mikheeva, E. A. Sakharitova
…pread of multidrug-resistant and extensively drug-resistant tuberculosis (MDR and XDR) requires the search and implementation of not only new diagnostic methods, but also innovations in the treatment of the disease. Aim. The assessment of current treatment options for multidrug-r…
Man Mohan Puri, Anil Kumar, Pooja Aneja, Rajnish K. Gupta, Lokender Kumar, et al.
…a, hypomagnesaemia, and hypocalcaemia have been reported in tuberculosis patients who have been treated with capreomycin.1-3 Capreomycin is recommended in the treatment of M. tuberculosis isolates resistant to kanamycin at baseline in multi drug resistant tuberculosis patients (M…
Samuel Pecho‐Silva, Ana Claudia Navarro‐Solsol, Vicky Panduro‐Correa, Jorge L. Maguiña, Ali A. Rabaan, et al.
Introduction: Multidrug-resistant tuberculosis is a significant public health problem for which drugs are used with many adverse effects. Among the devastating consequences of these diseases, there is a wide variation in the incidence of ototoxicity and hearing loss in patients w…
Siddharth G. Chatterjee, Arvind Pandey
Background: India has largest population of drug resistant tuberculosis, the treatment of which is long and full of adverse drug reactions. Despite the ongoing research in clinical and pharmacological aspects, quality of life in drug-resistant tuberculosis remains less explored. …
Vibha Mehta, Puneet Kumar Gupta, Mukesh Bairwa, Jakkula Sam Rahul
…ow no boundaries, severe global epidemics of drug resistant tuberculosis (DR-TB) pose a great health crises. Globally, World Health Organization (WHO) estimates that there are 484,000 new cases with resistance to first line drug rifampicin, of which 78% have MDR-TB (Multi drug re…
José-María García-García, Mercedes Sanz, José Antonio Gullón Blanco, Xavier Clop i García, Joan Pau Millet Vilanova, et al.
…and follow-up studies of patients with rifampicin-resistant tuberculosis in Spain. <bold>Aim:</bold> The aim of the study is to determine the characteristics and follow-up of patients with rifampicin-resistant tuberculosis alone (RR-TB) or extended (multidrug-resistant tuberculos…
D. V. Donchenko, Mikhail Chushkin, E. V. Krаsnikovа, Mammad A. Bagirov
BACKGROUND: Despite the success of the fight against tuberculosis, the proportion of patients with multidrug- and extensively drug-resistant pathogens continues to grow. According to the World Health Organization, the effectiveness of treating patients with multidrug- and extensi…
Valentina Aksenova, Н. И. Клевно, А. И. Казаков, D.А. Kudlаy, А. Д. Пахлавонова, et al.
…ren with multidrug-resistant and extensively drug-resistant tuberculosis (MDR / XDR-TB) is a difficult task due to many factors: the duration of treatment, the lack of drugs with children’s dosages, age restrictions (according to the drug instructions). Purpose of the study. To a…
M. P. Tatarintseva, Т. Л. Батищева, I. N. Demidkov, A.R. Aroyan, A. V. Miletskiy
…Chemotherapy is the main component used in the treatment of tuberculosis. In addition to chemotherapy, pathogenetic treatment holds a special place in the complex treatment. The inhaled tauractant therapy restores phospholipid content on the surface of the alveolar epithelium, st…