Showing 176–200 of 200 documents
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Bela Verma, S Fouziya Sultana, Amin Kaba
Childhood tuberculosis is a formidable problem in present times. Although the principles of diagnosis and treatment remain the same in children and adults, yet the dissimilarities in the pathology and the host bring up challenges while dealing with pediatric TB. Just as children …
Lavleen Singh, Pallavi Sinha, Dhulika Dhingra
Congenital tuberculosis (CTB) is a rare disease presenting in infants with very few cases reported despite a high burden of tuberculosis. The fewer reported cases reflect in part the difficulty in making a definitive clinical diagnosis as signs and symptoms are non- specific alon…
Turgut Teke
Abstract Tuberculosis-related pleural effusion (TPE) is reported in 12 to 38% of thoracic tuberculosis (TB) cases in the pediatric population. In TPE, the pleural fluid bacilli load is very low, generally resulting in negative acid-fast bacill (AFB) staining and Mycobacterium cul…
Sofia Kostoudi, Robert Hammond
ABSTRACT Background Tuberculosis (TB) is the second leading infectious killer after COVID-19 and the 13 th leading cause of death worldwide. Latent tuberculosis (LTBI) has become a major pool of potential active tuberculosis cases and is propelling the TB global health burden fur…
Miguel Ángel Medina Pabón, Martha Johnston, Jefferson Antonio Buendía Rodríguez, Javier Enrique Fajardo Rivero
Background, the cost-effectiveness of Tuberculosis (TB) diagnosis remains challenging and poorly understood. TB remains a significant public health issue in Colombia due to its high transmissibility and lack of accessibility to health services for timely diagnosis and management,…
Alejandro Rojas Urrea, Daniela Marino, Ana María Rojas-Faura, Mónica Liseth Holguín Barrera, Lorena García Agudelo
Tuberculosis is known as “the great mimicker.” Extrapulmonary tuberculosis accounts for approximately 20% of all cases, with about 10% of these involving the intestines. The ileocecal region is the most common site due to its high density of lymphoid tissue, slowed intestinal tra…
Diwan Israr Khan, Samreen Gul Khan, Nawalur Rehman Khan
…rounding the authenticity of the Montoux test in diagnosing tuberculosis among these groups. It was inferred from the study that a significant figure of the children with positive tuberculin skin test was not found to be diseased with tuberculosis and those with negative test res…
Afonso, Nuno Gonçalo do Amparo Leitão
ABSTRACT - Background: Reducing tuberculosis (TB) mortality and morbidity requires minimal delay from onset of symptoms to diagnosis (total delay), and its two subcomponents (patient and healthcare delays). This systematic review aims to study pulmonary TB diagnosis delay associa…
Yelda Sorguç, Miray Çelebi Yılmaz, Fahri Yüce Ayhan, Yakup Yaman, Şener Tulumoğlu, et al.
…agnostic method, in children and adolescents with suspected tuberculosis in a country with a high burden of tuberculosis. Method: This study included 581 children and adolescents aged 4 - 19 years who were suspected of having tuberculosis, were latently infected with Mycobacteriu…
Joy Morcilla, Ma. Liza Antoinette Gonzales, Anna Lisa Ong‐Lim
…y TB in children remains to be a burden in the Philippines. Diagnosis remains to be a challenge for pediatricians due to its paucibacillary nature, difficulty in obtaining specimens, cost of test as well as the varied sensitivity of the different tests available. Gastric aspirate…
M Ramos Martins, Lucas Tenório Soares Carvalho, Thiago Fabiano da Silva Carvalho, Isabel Gomes
…evaluate the impact of the COVID-19 pandemic on in-hospital diagnosis of tuberculosis in non-HIV patients. <b>Methods:</b> Single-center retrospective study comparing adult hospitalised patients with TB not associated with HIV infection, admitted from March 2018 to June 2019 (pre…
Bineeta Kashyap, Neha Gupta, Pooja Dewan, Puneeta Hyanki, NarendraPal Singh
Objectives Childhood tuberculosis (TB) accounts for 10–20% of all TB cases, with tuberculous meningitis (TBM) being the leading cause of severe morbidity and mortality. Pathophysiology of TBM still remains obscure. Tumor necrosis factor-α (TNF-α) induces fever and activation of h…
Ana Alice Amaral Ibiapina Parente, Rafaela Baroni Aurílio, Clemax Couto Sant’Anna, Maria de Fátima Bazhuni Pombo Sant’Anna, Afrânio Lineu Kriski, et al.
…uction in the value of the detection limit of Mycobacterium tuberculosis(M. tb.) from 116(from Xpert) to 15.6 CFU. The classification of bacillary load is: high, medium, low, and traces. In Brazil, in children(under 10 years) and in extrapulmonary tuberculosis(EPTB), the result o…
Ariarathinam Newtonraj
India is striving hard to eliminate Tuberculosis by 2025. One of the steps is the introduction of modern diagnostic tools in public health to improve the total tuberculosis notification. In our observation of 10 years in the National Tuberculosis Elimination Programme in a union …
Altynai Zhumabekova
…diagnosed with tuberculous meningitis and miliary pulmonary tuberculosis (TB) during her 16th week of pregnancy. The patient presented with symptoms such as vomiting, severe debilitation, lethargy, and loss of appetite. Chest radiography revealed pulmonary TB with a disseminated …
Hebert Dedehouanou, Yazid Taïrou Toure, Laurence Yehouenou
The diagnosis of bacteriologically confirmed pulmonary tuberculosis in Benin and in other developing countries relies on the search for acid-fast bacilli through microscopy despite its limited sensitivity. The objective of this study is to evaluate the contribution of the Xpert t…
Noha M. Abu Bakr Elsaid, Amany Refaat, Lamiaa Fiala, Eman Hamed
Delayed diagnosis of tuberculosis (TB) can enhance the transmission of infection and worsen prognosis. To identify the risk factors of delay in the management of TB cases for early management. A cross-sectional analytic study was performed to assess the proportion, duration of de…
Tran Thi Van Anh, Phan Viet Hai, Do Thien Hai, Trinh Cuong Loi, Phạm Trung Kiên, et al.
Abstract: Objective: Some factors related to the diagnosis of tuberculous meningitis at the National Children's Hospital (2019 - 2024). Subjects and methods: Cross-sectional descriptive study of 50 children from 1 month to 15 years old diagnosed and treated for tuberculous mening…
Titus Divala, Elizabeth L. Corbett, Neil French, Chikondi Kandulu, Peter MacPherson, et al.
Background: Tuberculosis (TB) diagnostic algorithms often include ‘trial-of-antibiotics’— empirical antibiotics for mycobacteriology-negative individuals to treat infectious causes other than tuberculosis, as a ‘rule- out’ diagnostic test for tuberculosis. We investigated the eff…
Kani Dayal Khare, Krishnendu Maiti
Abstract Tuberculosis secondary affects the genitourinary system, has vague symptoms, and is uncommon in children younger than 3–10 years. Renal thimble bladder (TB) damage, including renal failure and decreased bladder capacity, results from a delayed diagnosis. Here, we will di…
Kedir Usmael, Tsegahun Manyazewal, Hussen Mohammed, Getnet Yimer, Lemessa Oljira, et al.
…ren share 12% of the global 10 million people infected with tuberculosis (TB) each year. Closing case detection gap in children remains difficult, with 56% of all children and 65% under-five with TB missed each year. We aimed to assess the patterns of childhood TB diagnosis and u…
Beuy Joob, Viroj Wiwanitkit
… “Performance of Interferon-Gamma Release Assay (IGRA)s for Tuberculosis Screening in Pediatric Inflammatory Bowel Disease” with great interest (1). Stevens et al noted that “IGRA's are a useful tool to screen for LTBI, both prior to anti-TNF therapy and during treatment (1).” Th…
Fatma Tuğba Çetin, Emine Kocabaş, Özlem Özgür Gündeşli̇oğlu, Ümmühan Çay, Derya Ufuk Altıntaş, et al.
ÖzGiriş: Romatizmal hastalıklarda, tümör nekrozis faktör-alfa (TNF-α) blokörü ilaç kullanımı sonrasında tüberküloz gelişme riskinin 1.6-25.1 kat arttığı bildirilmiştir.Bu nedenle, TNF-α blokörü ilaçları kullanacak hastaların latent tüberküloz enfeksiyonu gelişim riski açısından t…
Olivier Marcy, MD, Vibol Ung, MD
Childhood tuberculosis (TB) accounts for 11% of the total 9 million annual TB cases and the difficulty of its diagnosis is increased in case of HIV infection in children. The aim of this study is to improve TB diagnosis in HIV-infected children by developing a new diagnostic alg…
Lucas Gabriel Quadros Ramos, Fernanda Moreira Soares Boaventura Silveira, Jessica Elen Martins Alves, Karina Andrade de Prince
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, considering that this comorbidity represents a public health problem, it is of paramount importance to understand the associated clinical, epidemiological, and economic factors due to its high prevalence …