Showing 151–175 of 200 documents
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Ying Luo
…otal role in interrupting the transmission of Mycobacterium tuberculosis (MTB). However, the development of sensitive and reliable diagnostic approaches for TB remains a significant unmet need, underscoring the necessity for innovative methods that can be translated into clinical…
Jinish Doshi, Kunal Deokar, Priyanka Gaikwad
Dear Editor, We are impressed by the article titled "Latent tuberculosis diagnostics: current scenario and review" by Gupta et al., published in your journal...
Lei Gao, Zhusheng Quan, Jun Cheng, Qi Jin
…h for MTB infection testing might be a favorable choice for tuberculosis control in schools in China.
Roslin Jose, Suchit Thapa Chhetri, Eleena Dhakal, Erica L. Stockbridge, Miller, Thaddeus
Background: Tuberculosis (TB) remains a threat to public health, both globally and within the US. An estimated 80% of active TB cases in the US are from reactivation of latent TB infection (LTBI). Reactivation is preventable with proactive, targeted LTBI screening and treatment b…
Trevor M Stantliff, Argita D. Salindri, Rocío Egoávil-Espejo, Ashton D. Hall, Laura Medina-Rodríguez, et al.
Summary Tuberculosis infection (LTBI) has been associated with increased cardiovascular risks. We aimed to characterize abnormal blood pressure (BP) readings in individuals with LTBI. We conducted a retrospective study of adults with LTBI presenting for their initial medical visi…
Patrick Lungu, Duncan Chanda, Gershom Chongwe, Shabir Lakhi
…ective was to establish the prevalence of latent and active tuberculosis in bedside contacts of smear-positive index patients and associated risk factors.
 METHODS 
 We recruited bedside contacts of smear-positive TB patients in medical wards and contacts of surgical pa…
Zikun Huang, Cuifen Xiong, Qing Luo, Juxiang Zhu, Yongqin Guo, et al.
Despite efforts to control it, tuberculosis (TB) remains a significant challenge in the field of public health globally.1 Timely diagnosis of active TB is essential to control disease transmission.2 A recently discovered group of small non-coding RNAs, namely transfer RNA-derived…
Aykut Eşki, Velat Şen
…anti- TNF-α agents risk various infections, especially tuberculosis (TB). We determined the incidence of latent TB infection (LTBI) and TB development and assess the follow-up protocol of patients using anti-TNF-α therapy. Methods: Children aged under 18 years prescribe…
Junling Wang
… individualized nursing intervention on patients with activetuberculosis (ATB) and latent tuberculosis infection (LTBI). Methods: The nursing study started in January 2020 and ended in January 2023. A total of 60 patients with ATB and LTBI were included, and they were divided int…
…ncluding TNF inhibitors (TNFi), increase the risk of latent tuberculosis infection (LTBI) activation, and TB screening before initiating systemic therapy is recommended. Safety outcomes in LTBI+ patients with moderate-to-severe psoriasis (PsO) or active psoriatic arthritis (PsA) …
Daut, Ummi Nadira, Abdul Aziz, Tasnim
Despite the significance of latent tuberculosis infection (LTBI) treatment, its acceptance among healthcare workers (HCW) is lower than non-HCW. It is important to identify the factors that contribute to the lack of adherence to LTBI treatment among HCW.
Roxana Mansour Ghanaie, Abdollah Karimi, Leila Azimi, Seddon James, Mahshid Nasehi, et al.
…tuberculous infection (LTBI) in child household contacts of tuberculosis (TB) cases, the national programs in high-burden TB regions rarely implement adequate screening of this high-risk group, mainly because of resource limitations. We aimed to evaluate the prevalence of LTBI am…
Rebecca F. Baggaley, Carolin Vegvari, Christian Akem Dimala, Marc Lipman, Robert F. Miller, et al.
<b>Introduction:</b> In lower tuberculosis (TB) incidence countries (<100 cases/100,000/year), screening and preventive treatment (PT) for latent TB infection (LTBI) among people living with HIV (PLWH) is often recommended, yet guidelines advising which groups to prioritise for s…
Arya Marganda Simanjuntak, Indra Yovi, Patricia Dean Ully Marbun, Adinda Elisabet
Introduction: Globally, cases of pulmonary tuberculosis (PTB) are rising by 4%, while new cases have declined in many nations, most notably by 14% in Indonesia. During the COVID-19 pandemic, the number of undiagnosed and untreated PTB patients could rise and infect more people. I…
A Trindall, A Popay, J Heywood, T Sutton, S Sharman, et al.
<h3></h3> Between 2011 and 2019, 10 tuberculosis (TB) cases were linked to a cluster via strain typing and/or whole genome sequencing. Four further cases were identified in quick succession at the end of 2019 into early 2020. Overall, 13 of the cases had either pulmonary or pulmo…
Yong Fang, Yuan Tang, Na Wang, Qiao-Xia Luo, Liang Tang, et al.
…e a potential new therapeutic evaluation indicator for anti-tuberculosis (TB) treatment. Methods : Newly diagnosed active pulmonary TB patients, latent TB infection (LTBI) and healthy controls were enrolled from January 2021 to December 2021. PTB patients were treated by standard…
Wiwiek Setiowulan, redi rulandani, Helmy Rachman
…ay and no symptoms of TB. Therefore, the patient has latent tuberculosis infection (LTBI) but overdiagnosed as TB disease. Due to the negative HIV status of the patient, TB prophylaxis is not indicated. Therefore, reintroduction of ATT was contraindicated, which led to lack ident…
Phillip Ssekamatte, Obondo James Sande, Reinout van Crevel, Irene Andia Biraro
<h3>Background</h3> Tuberculosis (TB) is one of the leading causes of death from a single infectious agent with approximately 1.4 million deaths annually. Efforts to eradicate TB are threatened by diabetes mellitus (DM), which confers a greater than a 3-fold TB disease risk. Both…
Martin Dedicoat
A quarter of the world's population may be infected with tuberculosis (TB). In the majority of these people the infection will remain dormant. A variety of risk factors may lead to this latent TB infection (LTBI) becoming active. Treatment of LTBI has been shown to reduce the ris…
Simone Villa, Marino Faccini, M. Pontello, Mario Raviǵlione, Maurizio Ferrarese, et al.
…ratory flows to Italy from countries with high incidence of tuberculosis (TB), especially those in Sub-Saharan Africa and the Indian subcontinent, have increased. Social issues and p...
Abu Taleb, A.M.F., El Sokkary, R.H., El Tarhouny, S.A.
…test [TST] has many limitations for the diagnosis of latent tuberculosis [TB] infection. The aim of this study in Egypt was to estimate the usefulness of an interferon-gamma release assay [IFN-gamma] assay for the detection of latent TB infection in contacts of active TB cases. A…
Lisa Kawatsu, Kazuhiro Uchimura, Akihiro Ohkado
Abstract Background Screening for latent tuberculosis infection (LTBI) among migrant population has become a critical issue for many low TB burden countries. Evidence regarding effectiveness of LTBI programs are limited, however, partly because of paucity of national data on trea…
Nirven Kumar, Cain Kapiri
…ation (WHO) has classified Papua New Guinea (PNG) as a high tuberculosis (TB)-burden country; therefore, the risk for TB infections among camp residents is high. ExxonMobil PNG (EMPNG) implemented a TB screening program using the QuantiFERON-G (QFT-G) screening method. The object…
Aldon Li, Tawny Belleau, Graciela Faiad
…s (IGRA) facilitate screening of patients exposed to active tuberculosis (TB), but the clinical utility of TB screening tests in determining management of exposed high-risk patients is not well described. Because the sensitivity of TB screening tests is dependent on patient’s imm…
Salmaan Keshavjee, T. Nicholson, Aamir J. Khan, Lucica Diţiu, Paul E. Farmer, et al.
…; participants then received treatment for active or latent Tuberculosis (TB) as needed. Local coalitions can use the experiences and framework to inform how to tailor the own efforts to drive down TB rates one community at a time. Additionally, TB is driven by poverty and is its…