Showing 101–125 of 200 documents
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Mohsen Heidary, Saeed Zaker Bostanabad, Amini SM, Ameneh Jafari, Ghalami Nobar M, et al.
…ran, IranEmail davood_darban@yahoo.comBackground: Nowadays, tuberculosis (TB) is one of the top ten leading causes of mortality worldwide. The emergence of multidrug-resistant (MDR) – and extensively drug-resistant (XDR) – Mycobacterium tuberculosis (M. tuberculosis) …
Karan Varshney, Frasso, CPh, Rosemary, DrPH Leader, et al.
Tuberculosis killed more people in 2018 than any other single infectious disease. In recent years, there has been an upsurge in cases of drug-resistant tuberculosis. Considering both that antibiotic resistance has been described as a global crisis, and that strains of tuberculosi…
М. В. Павлова, О. V. Lushina, A. I. Anisimova, Л. И. Арчакова, P. K. Yаblonskiy
… devoted to the effectiveness of the treatment of pulmonary tuberculosis with multiple (MDR) and broad drug resistance (XDR) M. tuberculosis (MBT) in patients after the end of the main course of treatment (intensive and continuation phase), which were observed with clinical cure …
A. A. Akzhigitova, T. N. Ignatova, A. К. Konratov, M. В. Теn
…f choice in therapy for extensively and multidrug-resistant tuberculosis. It is indicated for children from a 6-year age and young adults as part of a combination chemotherapy, in compliance with the medical council’s (MC) regulation on active extensively and multidrug-resistant …
Sora Yasri, Viroj Wiwanitkit
Emergence of drug-resistant tuberculosis has become an important public health problem at present[1]. In Indochina, especially for Myanmar and Thailand, the extensively drug-resistant Mycobacterium tuberculosis is an emerging problem[2]. The extensively drug-resistant M. tubercul…
Yitagesu Habtu, Tesema Bereku, Girma Alemu, Ermias Abera
… among thirty high burden countries of multi-drug resistant tuberculosis (MDR-TB) in the regions of world health organization. Contextual evidence on the emergence of the disease is limited at a program level. </sec> <sec> <title>OBJECTIVE</title> The aim of the study is to explo…
Alfi Rahmatika, Muhammad Mufaiduddin, Innelya Innelya
Background: Tuberculosis (TB) is one of the major causes of death in the world with the number of cases reaching millions every year. TB is caused by Mycobacterium tuberculosis. The occurrence of mutations in M. tuberculosis that cause resistance to anti-tuberculosis drugs has be…
Marie Sjölin Wijk
Tuberculosis remains the leading cause of death from a single infectious agent globally, posing a significant threat to public health. This highlights the need for improved treatment strategies to enhance outcomes and limit the emergence of resistance. Optimizing therapy requires…
П. А. Хромова, С. Н. Жданова, Natalia Solovieva, V. V. Sinkov, Sergey M. Masharsky, et al.
…uded in the list of 30 countries with the highest burden of tuberculosis, including MDR tuberculosis. The most important part of this problem is the primary MDR/XDR TB in children. The aim: a comparative analysis of the phenotypic and genotypic profile of drug resistance to anti-…
Pengwei Lou, Jiandong Yang, Yaoqin Lu, Yanggui Chen, Jiabo Xu
This study aims to predict the future incidence of tuberculosis in Urumqi using a dynamic model that incorporates pathogenic molecular characteristics. Sputum samples from tuberculosis patients in Urumqi were collected from 2017 to 2021. Following mycobacterium tuberculosis cultu…
A. A. Zhurilo, A. I. Barbova
…lence of multidrug-resistant and extensively drug-resistant tuberculosis in the era of human immunodeficiency virus infection poses a serious threat to effective tuberculosis control. Drug resistance in M. tuberculosis occurs due to lowfrequency spontaneous chromosomal mutations.…
Subendu Sarkar, Rajender Pal SİNGH
…owever, the effect of these phytochemicals on Mycobacterium tuberculosis is yet unknown. Treatment of multi-drug resistance (MDR) and extensively drug-resistant (XDR) strains of the tuberculosis bacterium are still challenging. Therefore, there is an urgent need to overcome this …
Oluwabusola Oluwakorede Asenuga, James Ponman Sargwak, Emmanuel Chimeh Ezeako, Matthew Babalola, Faith Omosigho, et al.
Background: The continuous evolution of drug-resistant Tuberculosis strains around the globe, particularly in West Africa, continues to be a major public health problem and poses serious threats to the actualization of the ”End Tuberculosis Strategy” projected by 2030. Hence, a c…
Bhawna Chaudhary
Abstract: Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis (TB), which is a primary cause of mortality and morbidity worldwide. Mtb during course of time re-established themselves to evolve into Multi Drug Resistant Strains (MDR) and extensively Drug Resist…
Ravindra Kushwaha, Rajeev Kumar, Ram Awadh Singh Kushwaha
Drug resistant tuberculosis (DR-TB) is a serious health issue worldwide and a number of mechanisms have been suggested which are involved in developing resistance in Mycobacterium tuberculosis to anti-tuberculosis drugs. In the Indian perspective, the pattern and prevalence of dr…
Moses Mpeirwe, Ivan Mugisha Taremwa, Patrick Orikiriza, Patrick Engeu Ogwang, Duncan Ssesazi, et al.
Tuberculosis (TB) remains a public health challenge and one of the leading causes of death worldwide. TB is preventable and curable. However, treatment of tuberculosis has continued to be difficult as a result of rapid increase of multidrug and extensively drug resistant strains …
Yousaf Jamal, Jamal Ahmad, Afsar Ali, Mahmood Iqbal Malik, Sultan Mehmood Kamran, et al.
Objective: To study the patterns of resistance to anti tuberculosis drugs in patients of drug resistant pulmonary tuberculosis. Study Design: Cross sectional analytical study. Place and Duration of Study: Department of Pulmonology, PEMH Rawalpindi from Jul 2016 to Dec 2017. Metho…
Pooja Jatav, Ruchi Khare Shrivastava
Tuberculosis remains a global health concern, necessitating the exploration of novel therapeutic strategies. Multidrug-resistant and extensively drug-resistant strains of Mycobacterium tuberculosis pose a growing challenge in tuberculosis treatment. Drug resistance can reduce the…
…The article is devoted to the effectiveness of treatment of tuberculosis with MDR-TB and XDR-TB mycobacteria after the main course of chemotherapy. The treatment of tuberculosis with multiple and broad MD MBT is a com-plex and urgent task. Prescribing the latest generation of dru…
Alexey M. Tikhonov, A. Zakharov, M. V. Burakova, Olga Gordeeva, E. V. Krаsnikovа, et al.
Introduction. The problem of mycobacterium tuberculosis resistance requires the effective implementation of a strategy to curb the growth of the pathogen’s drug resistance, namely, monitoring the competent administration of anti-tuberculosis drugs, and developing new chemotherapy…
Alexey M. Tikhonov, A. Zakharov, M. V. Burakova, Olga Gordeeva, E. V. Krаsnikovа, et al.
Abstract. Introduction. The problem of mycobacterium tuberculosis resistance requires the effective implementation of a strategy to curb the growth of the pathogen’s drug resistance, namely, monitoring the competent administration of anti-tuberculosis drugs, and developing new ch…
Luísa Heinzen Cescon, Ana Júlia Probst Nichellatti
Drug-resistant tuberculosis represents one of the main challenges for disease control in Brazil. Cases of multidrug-resistant tuberculosis (TB-MDR) and extensively drug-resistant tuberculosis (TB-XDR) increase treatment duration, costs, and the risk of unfavorable outcomes. This …
Askar Zetov, Kulakhmed Erimbetov, Nargiza Parpieva, Bolat Zhetibayev, Abzal Malbaskanov
…roach in treatment of multi- and extensively drug-resistant tuberculosis.Design:The article described a retrospective analysis of surgical treatment of 246 multi- and extensively drug-resistant tuberculosis patients who were divided into 3 groups: 152 multi-drug-resistant tubercu…
Harald G. Wiker
Recent studies challenge the traditional belief that latent tuberculosis is a lifelong condition. Analysis of tuberculosis decline in low endemic areas suggests that latency is diminishing, and a significant proportion of individuals likely clear the infection each year. The risk…
O. I. Bobokhodzhaev, U. Yu. Sirodzhidinova, R. M. Nurov, B. P. Pirmakhmadzoda, Abdurakhimov A.Kh. Abdurakhimov, et al.
…ctiveness of treatment of multiple drug resistant pulmonary tuberculosis (MDR TB) with different chemotherapy regimens in the Republic of Tajikistan. Subjects and Methods. To achieve this objective, the prevalence of drug resistant tuberculosis in 2009–2020 was studied by analyzi…