Showing 101–125 of 200 documents
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Harsini Harsini, Umarudin Umarudin, Jatu Aphridasari
<b>Background:</b> The problems of prevention of tuberculosis (TB) are become more complex with the presence of Mycobacterium Tuberculosis which drug resistant called multi drug resistant tuberculosis (MDR-TB). The IL-10 1082 G/A gene polymorphism is associated with the secretion…
Dina Bisara Lolong, Joko Irianto, Ina Kusrini, Ingan Ukur Tarigan, Alfons Maryono Letelay, et al.
…alyze the risk factors associated with multidrug- resistant tuberculosis (MDR-TB) as a first national survey in Indonesia. Methods: This national coverage cross-sectional study was conducted from 2017 to 2018. The study subjects were selected using a multi-stage probability rando…
Yassir Adam Shuaib
The Sudan is a high tuberculosis (TB) burden country (i.e. 77 per 100,000 population). Specifically, the eastern part of the country is endemic with high incidence rates of TB reaching up to 275 per 100,000 population during the past decade. Prevalence of Mycobacterium tuberculos…
Seung Wook Hong, Sang Hyoung Park, Byong Duk Ye, Suk‐Kyun Yang
Differentiating between intestinal tuberculosis (ITB) and Crohn’s disease (CD) remains a challenge for gastroenterologists. In Asia, where the prevalence of tuberculosis is relatively high and the incidence of CD is rapidly increasing, this issue is crucial. Here we report a case…
Yu. А. Sheyfer, I. S. Gelberg
…eatment outcomes in patients with pulmonary destructive MDR tuberculosis who completed the intensive phase of treatment and had healed or persisting cavities. Subjects and methods . Treatment outcomes were retrospectively analyzed in 191 patients suffering from destructive pulmon…
Shianny Natasha Suwandi, Iceu Dimas Kulsum, Basti Andriyoko
Background: Indonesia has the second-highest tuberculosis prevalence in the world. Moreover, Indonesia is among the 30 countries with the highest burden of multidrug-resistant tuberculosis (MDR-TB). This study aimed to determine the pattern of second-line anti-tuberculosis drug r…
Dinda Nursyafira Misyatin, Arto Yuwono Soeroto, Ferdy Ferdian
Background: Diagnosis of drug-resistant tuberculosis (DR-TB) begins with identifying presumptive DR-TB patients using Xpert MTB/RIF, as a diagnostic test to detect resistance to rifampicin. The study aimed to identify the distribution of rifampicin-resistant tuberculosis (RR-TB) …
Hema Malini, Emil Huriani, Devia Putri Lenggogeni, Shinta Herlina
The high incidence of multidrug-resistant tuberculosis (MDR-TB) in the community due to the lack of socialization or the provision of health education about MDR-TB. During this time, health education is only focused on tuberculosis (TB) generally. The purpose of this study was to…
ArunabhaDatta Chaudhuri
… of guidelines of programmatic management of drug resistant tuberculosis in India 2019 by Revised National Tuberculosis Control Programme, Central TB Division, Directorate General of Health Services, Ministry of Health & Family Welfare, Nirman Bhawan, New Delhi, integrates use of…
Nayereh Ebrahimzadeh, Shiva Irani, Shohreh Khatami, Seyed Davar Siadat
Background: Tuberculosis is a threat to public health. The epidemiology of tuberculosis can be effective in identifying the source of infection, the dominant circulating strains and achieving transmission pathways in the world. The aim of this study was to determine the genotype …
Ashutosh Kumar, Rishabh Kumar Rana, Shalini Sundram, Sudipta Sinha, Richa Jaiswal, et al.
… The aims and objectives were to study the progression from tuberculosis to multi drug resistance-TB in revised national tuberculosis control programme: perspectives from health system care givers.Methods: The study was carried out in TB Sanatorium ITKI, Sadar Hospital Ranchi and…
Alireza Jafari, Masoomeh Taziki, Hesamaddin shirzad Aski, Ali Mojtahedi, Nasser Behnampour, et al.
Aims and objectives: Tuberculosis (TB) is estimated to have caused the deaths of 1 billion people in the last 200 years. Methods: In the first step, the microplate alamar blue assay (MABA) was used for the detection of seventy-eight clinical isolates from Golestan Regional Tuberc…
Neetha S. Murthy, Sanjeev Nair, P. Ramya, Renu Susan George, B Ravikrishnan, et al.
…e data regarding drug-resistant evolutionary genetics of M. tuberculosis (MTB) remains sparse in India. Our objective was to determine the genotypic drug resistance mutation pattern for Rifampicin and Isoniazid of MTB isolates to gain an understanding of the prevailing molecular …
Hanouf Niyazi
…ons of current and new drug regimens and the response of M. tuberculosis to treatment are complicated and time consuming. Other issues include the need for accurate and early detection, drug resistance screening and follow-up measures to ensure treatment completion as intended. T…
World Health Organization. Regional Office for Europe
While decreasing trends in tuberculosis (TB) incidence and mortality rates represent major achievements in TB prevention and care in the WHO European Region and eastern Europe and central Asia (EECA), the still alarmingly high rates of drug-resistant TB (DR-TB) and of TB/HIV coin…
Ayaz Ali Unar, Abdullah Dayo, Muhammad Ali Ghoto, Khalida Unar, Muhammad Ali Khokhar
Background: Anti-tuberculosis drug resistant is a major public health problem worldwide. It arises due to improper use of anti-tuberculous drugs in susceptible TB patients. The objectives of this study were to evaluate treatment outcomes and adverse effects of drug resistant tube…
A. Noorjahan, B. Bhargavi, K. Mallikarjuna, Bushra Ishaq, L.S.S. Varaprasad Reddy, et al.
Tuberculosis (TB) is a communicable systemic infectious disease with high morbidity and mortality associated with it. Resistance to medications used to treat tuberculosis has been on the rise in recent years. (multidrug-resistant tuberculosis) (MDR-TB) is a significant challenge …
Zhao ZL, L Chen, H Zhang
Zhao-Liang Zhao,1 Ling Chen,1 Hong Zhang1,2 1Tuberculosis Division of Respiratory and Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, People&amp;rsquo;s Republic of China; 2Z-BioMed, Inc., Rockville, MD 20855, USACorrespondence:…
Mariano Guillermo Bonanno
Background: Multidrug-resistant tuberculosis (MDR-TB) caused by Mycobacterium tuberculosis mainly affects the respiratory system but can spread to other organs. Its resistance arises from inappropriate use of antibiotics, complicating treatment. Its control depends on rapid diagn…
World Health Organization. Regional Office for Europe
…been published at the global and European levels to support tuberculosis (TB) elimination and the management of TB infection. These warrant a review of the available reports and their implications for the WHO European Region. This publication aims to guide Member States in the Re…
Yusup Subagio Sutanto, Magdalena Sutanto, Agnes Sri Harti
…changes in bacterial profiles related to resistance to anti-tuberculosis drugs (ATD) which can affect the incidence rate of MTB and MDR-TB in a region. The research objective was to analyze the effectiveness of the type of ATD against the resistance level of Mycobacterium tubercu…
Onyeche Vange, E. Uhl, T. Azua E.
Tuberculosis (TB) has become a global health challenge; it is a serious problem in sub-Saharan Africa, where rates of Human Immunodeficiency Virus (HIV) co-infection and drug resistance are high. The prevalence and rifampicin (RIF) resistance of Mycobacterium tuberculosis (MTB) a…
Harit Anon, Varsha Singh, Sonia Mehta, Shavi Nagpal, Rosy Bala, et al.
Background: Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide, despite being a treatable and preventable disease. The emergence of Multi Drug Resistant (MDR) TB had exacerbated the situation further. To prevent the spread of infection & to accelerate t…
Ranjitha Shankare Gowda, M. A. Bkar Pk, Raghavendra Rao M, Krishna Karthik
Tuberculosis (TB), a dreadful disease known to mankind continues to be a problem in a developing country likeIndia. The incidence of people getting infected with TB is on the rise due to compounding factors like coinfectionwith the human immunodefiency virus and multidrug-resista…
Olajumoke Tubi Abiola, S. D. Gyar, Yakubu Boyi Ngwai, Jibril Egwu Owuna
Abstract Background: Tuberculosis (TB) remains a significant public health challenge in Nigeria, particularly with the emergence of drug-resistant strains. Accurate detection of Mycobacterium tuberculosis (MTB) and its resistance patterns is essential for effective disease manage…