Showing 76–100 of 200 documents
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Ameya D. Bendre, Pooja Singh, Swati Jaiswal
Tuberculosis: Recent Updates in Basic Research, Drug Discovery and TreatmentAmeya D. Bendre1, Pooja Singh2*, Swati Jaiswal3*1.Department of Chemistry, S. P. Pune University (formerly known as Pune University), Ganeshkhind, Pune 411007, IndiaCurrent affiliation: Gennova Biopharmac…
Samantha Pillay, Geraint Davies, Marty Chaplin, Margaretha de Vos, Samuel G. Schumacher, et al.
…ibility testing (DST). DST determines whether Mycobacterium tuberculosis bacteria are susceptible or resistant to drugs. Xpert MTB/XDR is a rapid nucleic acid amplification test for detection of tuberculosis and drug resistance in one test suitable for use in peripheral and inter…
L.M. Zahaba, M.S. Opanasenko, І. В. Ліскіна, О. V. Теreshkovych, O.O. Melnyk, et al.
…. To clarify the clinical forms of drug-resistant pulmonary tuberculosis with surgical treatment and their relationship with the morphological activity of specific inflammation and the detection of Mycobacterium tuberculosis (MBT) in the surgical material. MATERIALS AND METHODS. …
Ekramy Elmorsy, Basil D. M. Alruwaili, Hatem R. H. Alrwaili, Anwar S. J. Alrawaili, Abdulelah Alanazi, et al.
Background & objectives: Tuberculosis (TB) continues to be a significant global health issue, as an increasing number of individuals are presenting with severe, life-threatening conditions that require admission to intensive care units (ICUs). The management of critical care …
Amish Talwar, Clarisse A. Tsang, Sandy F. Price, Robert Pratt, William L. Walker, et al.
This report reviews the current status of tuberculosis in the United States, noting the declining incidence and describing the populations with the greatest prevalence. This report reviews the current status of tuberculosis in the United States, noting the declining incidence and…
Gudisa Bereda
Medication-resistant tuberculosis is a considerable across-the-board public health challenge that menace’s the substantial advance made in tuberculosis heedfulness and precluding in current decades. Multidrug-resistant tuberculosis is caused by organisms that are resistant to the…
Margherita Bracchi, Clare van Halsema, Frank A. Post, Funmi Awosusi, Alison Barbour, et al.
…f these guidelines is to help physicians manage adults with tuberculosis (TB)/human immunodeficiency virus (HIV) co-infection. Recommendations for the treatment of TB in HIV-positive adults are similar to those in HIV-negative adults. Of note, the term "HIV" refers to HIV-1 throu…
Gudisa Bereda
Mycobacterium tuberculosis strains that are resistant to an elevating number of second-line medicines used to treat multidrug-resistant tuberculosis are becoming a threat to public health worldwide. Recent guidelines recommended at least 20 months of treatment, but recent regimen…
Ngula Monde, Mildred Zulu, Mathias Tembo, Ray Handema, Musso Munyeme, et al.
…tries in sub-Saharan Africa is affected with drug resistant tuberculosis. However, the drug resistant tuberculosis situation over the years has not been described in various regions of the country. Consequently, this study aims to determine the drug resistant tuberculosis burden …
О.С. Шевченко, Svitlana Matveyeva, Anna Stepanenko, Olexandra Choporova, Olha Pohorielova
PECULIARITIES OF DRUG-RESISTANT TUBERCULOSIS IN UKRAINE AND KHARKIV REGION 
 Shevchenko O., Matveyeva S., Stepanenko A., Choporova O., Pohorielova O.
 Background. Multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis remain severe epidemic problem…
Getachew Kahsu Abay, Bahlibi Hailay
Abstract Background Tuberculosis (TB) is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. The emergence of Mono or multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis (XDR-TB), poses a considerable challenge to Mycobacter…
Cristina Daniela Marineci, Cristina Elena Zbârcea, Simona Negreș
Tuberculosis is a chronic infection, most often affecting the lungs, which usually manifests after a latency period from primary infection with Mycobacterium tuberculosis. Symptoms are generally nonspecific, with fever, cough, weight loss and malaise. The diagnosis is based on mi…
Christoph Lange, Yousra Kherabi, Lorenzo Guglielmetti, Raquel Duarte, Gunar Günther
…sistance testing for BPaLM regimen for rifampicin-resistant tuberculosis in Europe”, published in this journal ( 1 Günther G, Guglielmetti L, Kherabi Y, Duarte R, Lange C; Tuberculosis Network European Trials group. Availability of drugs and resistance testing for bedaquiline, pr…
О. М. Raznatovska, V.I. Petrenko, О.S. Shalmin, R.M. Yasinskyi, A.V. Fedorec, et al.
We present our own observation of the multifocal tuberculosis with pre-extensive drug resistance (pre-XDR-TB) development in a patient who was treated in the pulmonary tuberculosis department No. 2 of the Zaporizhzhia’ regional phthisio-pulmonology clinical treatment and diagnos…
Parissa Farnia, Ali Akbar Velayati
…mes with a new definition of pre-extensively drug-resistant tuberculosis (XDR-TB) and XDR-TB. New definitions for pre-XDR and XDR-TB helped to define more precisely groups of TB patients who require complex treatment regimens.[1] The definition of pre-XDR-TB applied to TB caused …
Shuang Wei, M.D.
Rifampicin-resistant tuberculosis (RR-TB) is characterized by a long treatment course, high incidence of adverse reactions, low cure rate and high recurrence rate. This is related to the large number of drugs in the RR-TB treatment regimen, high incidence of adverse reactions and…
Shuaibu Abdullahi Hudu
Tuberculosis is still the most prevalent infectious cause of mortality, and it has a significant medical, societal, and economic impact MDR-TB is a type of tuberculosis (TB) infection produced by bacteria resistant to at least two of the most important first-line anti-TB treatmen…
Jin Mo Goo, M.D.
…ultralow dose CT scan. Multidrug- or extensively resistant tuberculosis tuberculosis is a major public health threat worldwide and the global burden of drug-resistant tuberculosis is increasing. Drug-resistant tuberculosis is associated with long period and high costs for treatm…
T. I. Cookey, Sofiat Adewuyi-Oseni, I. O. Okonko, K. C. Anugweje
Aim: Mycobacterium tuberculosis (MTB), the causative agent of tuberculosis, is a strictly aerobic bacterium that grows fastidiously and slow, which is among the top 10 causes of death globally and the leading cause from a single infectious agent (above HIV/AIDS). Among the deadly…
Muhammad Akram, Abid Mahmood, Mohammed Khudhair Hasan, Isaac John Umaru, Hind A. Abdulghafoor, et al.
…s. Mainly affecting the lungs (pulmonary TB), Mycobacterium tuberculosis is a slow-growing, acid-fast bacillus that causes tuberculosis. However, it may also affect other organs, such as the lymph nodes, bones, central nervous system, and genitourinary tract. Due to a number of v…
Inna Friesen, Timo Ulrichs, L. A. Hryshchuk, H. S. Saturska
… to compare the epidemiological situation of chemoresistant tuberculosis in Germany and Ukraine, in addition analyzing the nature and features of chemoresistant tuberculosis in 192 patients treated at the Ternopil Regional TB Dispensary Ukraine during 2017—2018.
 Materials a…
Анна Старшинова, E. N. Belyaeva, Igor Kudryavtsev, Artem Rubinstein, Leonid P. Churilov, et al.
…Health Organization (WHO), nearly 10.6 million new cases of tuberculosis were detected in 2022, indicating an increase of 3.5 % from the reported 10.3 million in 2021. After the COVID-19 pandemic, the incidence of tuberculosis increased by 3.9 % from 2020 to 2022. According to th…
О. А. Пасечник, В. Л. Стасенко
…modeling the further development of the epidemic process of tuberculosis in several regions of the world, including the Russian Federation, indicate an unfavorable prognosis in the spread of multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis. Purpose of…
Balasundaram Revathi Mani, Usharani Brammacharry, Venkateswari Ramachandra, Suganthi Palavesam, Muthuraj Muthaiah
The emergence of drug-resistant tuberculosis jeopardizes the TB control programme activities globally. Multidrug-resistant TB is defined as tuberculosis strains resistant to at least two first-line drugs, rifampicin (RIF) and isoniazid (INH). Extensively drug-resistant TB refers …
O.B. Pikas, M.A. Semeniuk
…rience and professional publications on modern treatment of tuberculosis patients and its effectiveness was carried out.The analysis of literary sources of recent years indicates an urgent problem regarding tuberculosis in Ukraine (especially in the conditions of martial law and …