Showing 76–100 of 200 documents
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Microbiologist- External Quality Assurance, State TB control Society, Port Blair, Andaman and Nicobar Islands, Keerthivasan Gurumurthy
Introduction: Tuberculosis is a contagious bacterial infection affecting more than 10 million people worldwide. It is a major public health concern in India especially with the increasing numbers of drug-resistant cases of tuberculosis. Lack of early diagnosis, inadequate and ina…
Santosh Shankar Patil, Nilima Sanjay Naik, VR Patil
Tuberculosis (TB) remains a significant global health challenge, with increasing incidence of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) posing a threat to public health. This study aimed to analyze the genetic diversity of M. tuberculosis strains using RAPD fingerpr…
G. Edwar, N. Hayyin, D. Syahdita, Farchan Azzumar, Aulia Fitri Rhamadianti, et al.
…tract RATIONALE: A significant proportion of Drug-Resistant Tuberculosis (DR-TB) patients worldwide remains a global health burden with only 44% of patients receiving treatment. In 2023, the proportion of individuals with Multidrug Resistant/Rifampicin Resistant Tuberculosis (MDR…
Rehmadanta Sitepu, Fira Dwijayanti, Chresiani Destianita Yoedistira
The conversion phase in tuberculosis treatment examines patients to ensure the possibility of further advancement. Despite its low specificity, microscopic evaluation is a standard method at public health centers. Moreover, the biased results from this method form a new problem r…
Muhammad Bilal Ibrahim, Maria Cristina Cuartas-Mesa, Hiba Noor, Ali Husnain, Mihir Shah, et al.
Introduction: Tuberculosis (TB) is more frequently found among high-risk populations such as immigrants, with HIV, incarcerated, and homeless individuals in the US. it is still a significant public health concern as diagnosis and presentation represent a challenge, especially as …
Ahmad Alikhani, Elnaz Amini, Mohsen Arabi, Hamid Reza Goli
Abstract Background: Due to the significant prevalence of tuberculosis (TB) in Mazandaran and Golestan provinces in northern Iran, we aimed to investigate the gene mutations in resistant Mycobacterium tuberculosis isolated from pulmonary TB patients in these provinces of Iran. Me…
Ntandazo Dlatu, Lindiwe Modest Faye, Teke Apalata
…t programs, especially in areas with limited re-sources, as tuberculosis continues to be a major public health issue. The study aimed to evaluate clinical data from TB-infected pa-tients' clinic files in rural areas of the Olivier Reginald Tambo District Municipality, Ea…
D Gebretsadik, Naglaa Ahmed, Elias Kebede, Muneer Khan Mohammed, Belete MA
… Daniel Gebretsadik Email gebretsadikd@gmail.comBackground: Tuberculosis is a communicable disease that is a major cause of ill health, one of the top 10 causes of death worldwide, and the leading cause of death from a single infectious agent, even ranking above human immuno-defi…
Sanjida Bari Ananna, Sohidul Islam, Ishrat Jabeen, Ishtiaque Ahammad, S. M. Mostofa Kamal, et al.
Background: Multi-drug resistant (MDR) Tuberculosis (TB) is one of the most significant concerns in tuberculosis control. Genotyping of Mycobacterium tuberculosis helps study evolutionary relationships, its transmission, and molecular epidemiology. The collaborative data from gen…
Olutayo Israel Falodun, Idowu Simeon Cadmus, O. E. Fagade
The success of the global tuberculosis (TB) control program has been threatened with drug resistant strains emergence; especially the Multidrug Resistant Tuberculosis (MDR-TB). Despite that Nigeria is one of the countries with high tuberculosis burden, little is known on the magn…
T. I. Guryeva, Е. И. Никишова, Olga A. Zolotaya, O. M. Sveshnikova, Д. В. Перхин, et al.
…tablish effectiveness and safety of preventive treatment of tuberculosis with fluoroquinolones in children exposed to multidrug-resistant tuberculosis (MDR TB) in their families. Subjects and Methods. A cohort prospective study was conducted in Arkhangelsk Region from January 01,…
Maksi Puasa, Nur Chayati
…roduction: The increasing number of patients with resistant tuberculosis requires attention and efforts for prevention. Resistance causes more expensive cost of treatment, longer duration of treatment, more severe side effects and decreasing the chance of recovery. The specific p…
Aarthi Sridhar, Anjana Gopi, Abhilasha Dalal, Divya Ravi
…of 2 microscopic methods for the diagnosis of Mycobacterium tuberculosis (M.tb) along with culture and drug susceptibility testing to first line drugs. : The cross-sectional study comprises 200 suspected cases of pulmonary tuberculosis both clinically and radiologically in KIMS, …
Diah Syafriani, Rouly Pola Pasaribu, Zen Ahmad
MDR TB is a condition of M. tuberculosis that is resistant to isoniazid and rifampicin. This occurs because of certain genomic mutations in certain Mtb specific genes. Some of the genes that play a role in the INH mutation are the katG gene, the inhA gene, the ahpC gene, the ndh …
Ahmet Yılmaz, Dursun Erol Afşin
Objective: In the study, 419 Mycobacterium tuberculosis complex strains (MTC), which were isolated from samples sent to the Regional Tuberculosis Laboratory in our city between 2015 and 2019 with suspected tuberculosis from Erzurum and surrounding cities were investigated. Method…
Ahamed, Nisha, Yurasova, Yelena, Zaleskis, Richard, Grzemska, Malgorzata, Reichman, Lee B, et al.
Tuberculosis is an increasingly serious problem in the WHO European region, particularly in the countries of eastern Europe, the Baltic States, and the Commonwealth of Independent States (CIS).Primary health care providers can play an important role in tuberculosis control throug…
Konstantin Glebov, Anastasiia Russkikh, Anastasia Samoilova, O. V. Lovаchevа, I. А. Vаsilyevа, et al.
…s (DST) confirmation of drug resistance in newly identified tuberculosis (TB) patients is not possible, there is a serious problem when choosing the correct treatment regimen. Data on the drug resistance of the M. tuberculosis (MBT) source of infection can help in prescribing ade…
Olha Sakhelashvili-Bil
… children and 45 adolescents) from the multi-drug resistant tuberculosis sites underwent the complex clinical radiological and immunological examination. Insignificant functional disorders of cellular response (immunoregulatory processes) caused by the prevalence of suppressor an…
World Health Organization
…panies the third edition of the WHO operational handbook on tuberculosis, Module 3: Diagnosis, and provides technical information sheets on selected rapid diagnostic technologies for the detection of tuberculosis (TB) and drug-resistant tuberculosis (DR-TB). The document describe…
Anubha Singh
Many people believe that tuberculosis (TB), like smallpox, is a disease of the past, and they are surprised to learn that tuberculosis still exists in the United States. On a global basis, TB continues to be the leading cause of death for adults from an infectious disease. Despit…
Preeti Sharma, Alok Raina, Kavita Sharma
…o provide nutritional incentive of INR 500 per month to all tuberculosis (TB) patients till they complete their treatment. Aim of present study is to determine the number (proportion) of patients being treated for tuberculosis who received the benefits of NPY and to explore the wa…
Muhammad Bilal Ibrahim, Reyan Hussain Shaikh, Arshia Jahangir, Ali Husnain Khan, Hiba Noor
Tuberculosis is more frequently found among high-risk populations in the United States. It has a challenging diagnosis since it can present with diverse organ involvement that may delay the diagnosis. This is especially true regarding hepatic tuberculosis, with prevalence varying…
Arshad Javaid, Mazhar Ali Khan, Mukhtiar Zaman Afridi, Abdur Rab Khan, Abdul Ghafoor
…kground: Resistance to first-line drugs is a major issue in tuberculosis (TB) control. Globally 20% of previously treated TB cases have been reported to have multi-drug resistant tuberculosis (MDR-TB). Pakistan is among the top high TB burden countries with an annual incidence of…
Khalid Mokti, Zaleha Md Isa, Mohd Rizal Abdul Manaf, Firdaus Hayati, Syed Sharizman SYED ABD RAHIM
Undernutrition and tuberculosis (TB) are a vital issue in most developing countries of the world. Both of these medical problems tend to have interacted with each other and bidirectional. The undernutrition creates a more significant problem in patients with active TB rather than…
Shi W, Jing Wu, Tan Q, Hu Cm, Xiang Zhang, et al.
… Province, People’s Republic of China; 2Department of Tuberculosis, The Second Hospital of Nanjing, Nanjing, Jiangsu Province, People’s Republic of China; 3Department of Tuberculosis, The Third Hospital of Zhenjiang City, Zhenjiang, Jiangsu Province, People’s Re…