Showing 76–100 of 200 documents
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Sofia Kostoudi, Robert Hammond
ABSTRACT Background Tuberculosis (TB) is the second leading infectious killer after COVID-19 and the 13 th leading cause of death worldwide. Latent tuberculosis (LTBI) has become a major pool of potential active tuberculosis cases and is propelling the TB global health burden fur…
Chin-Chung Shu, MD
To follow-up the latent tuberculosis infection and the risk of developing active tuberculosis in patients receiving long-term dialysis Tuberculosis (TB) remains an important infectious disease worldwide. Taiwan is still an edemic area. In 2008, there is an incidence of 62 person…
Bwarenaba B Kautu
Tuberculosis (TB) is a deadly infectious disease caused by Mycobacterium tuberculosis (M. tuberculosis). Currently, it is the leading infectious disease killer in the world ranking above HIV/AIDS. Furthermore, the continued emergence and spread of drug-resistant forms of TB are i…
Charutha Retnakumar, Komala Ezhumalai, Ruben Raj, Prakash Babu Narasimhan, Subitha Lakshminarayanan, et al.
Introduction: Tuberculosis control remains an ongoing challenge for low and middle-income countries with lack of understanding of the factors determining transmission of infection. This study aimed to investigate the impact of alcohol use among pulmonary tuberculosis patients on …
Chin-Chung Shu, MD
To follow-up the latent tuberculosis infection and evaluate the risk of developing active tuberculosis in patients with severe chronic kidney disease or receiving long-term dialysis Tuberculosis (TB) remains an important infectious disease worldwide. Taiwan is still an edemic ar…
Saadiq Garba, Heidi Fischer, Lei Qian, Zhuoxin Li, Katia Bruxvoort, et al.
…ract Background California has the largest number of active tuberculosis (TB) cases in the US; more than 2 million Californians are estimated to have latent tuberculosis infection (LTBI), and 87% of TB cases in 2021 were attributed to LTBI reactivation. This study in a large Cali…
Thomaz Felipe Soares Arnizant, Filipe Andrade Bernardi, Tiago Lara Michelin Sanches, Nathalia Yukie Crepaldi, Thiago Nascimento do Prado, et al.
According to the World Health Organization (WHO), latent tuberculosis occurs through latent infection by Mycobacterium tuberculosis without evidence of active tuberculosis (TB) symptoms. As patients don’t develop the same symptoms as active TB, the treatment is abandoned before t…
Ebru Yalçın, Nagehan Emiralioğlu, Gökçen Dilşa Tuğcu, Sanem Eryılmaz, Mina Hızal, et al.
… there is strong evidence of its role in the development of tuberculosis(Tb) disease. Our aim is to determine the levels of vitamin D, cathelicidin B(LL-37) in patients with Tb disease, latent Tb infection(LTBI) and healthy children. Our second aim of this study is to determine t…
Mohau S. Makatsa, F. Millicent A. Omondi, Rubina Bunjun, Robert J. Wilkinson, Catherine Riou, et al.
ABSTRACT The development of a highly effective tuberculosis (TB) vaccine is likely dependent on our understanding of what constitutes a protective immune response to TB. Accumulating evidence suggests that CD4+ T cells producing IL-22, a distinct subset termed ‘Th22’ cells, may c…
Dewi Kartika Turbawaty, Adhi Kristianto Sugianli, Ahmad Rizal Ganiem, Ida Parwati
…AT-6), culture filtrate 10-kDa (CFP- 10), and Mycobacterium tuberculosis (Mtb) 64 (MPT-64) antigens are secreted by actively growing Mtb in active tuberculosis (TB) patients. Increased levels of ESAT-6, CFP-10, and MPT-64 at the site of infection facilitate the entry of antigens …
Anjum Hameed Dr. Manal Tanveer
…on of fund receiving forums and TB research implementation. Tuberculosis (TB) causes millions of deaths every year across the globe and it is ranked among most alarming infectious diseases. This research overviews general treatment guidelines, diagnosis and pathogenesis of TB. Be…
Patrick Lungu, Duncan Chanda, Gershom Chongwe, Shabir Lakhi
Background: Screening of contacts of tuberculosis (TB) patients is not routinely done in resourcelimited countries like Zambia despite the World Health Organization (WHO) recommendations, leading to missed opportunities for prevention, early diagnosis and high mortality.Objective…
Wenhong Zhang, PhD
…nal study is to investigate the proportion of Mycobacterium tuberculosis (MTB) infection in school contacts of active tuberculosis (ATB) patients. The main questions it aims to answer are: * the proportion of MTB infection among school contacts of ATB patients * risk factors rel…
Ulrich Mrowietz, Elisabeth Riedl, Stefan Winkler, Wen Xu, Himanshu J. Patel, et al.
To the Editor: Reactivation of latent tuberculosis infection (LTBI) and/or active tuberculosis (TB) has been associated with certain immunomodulatory therapies for psoriasis (Pso) or psoriatic arthritis (PsA).1Kaushik S.B. Lebwohl M.G. CME part II psoriasis: which therapy for whi…
Esther Uwimaana
Background: Tuberculosis (TB) diagnosis in the presence of HIV co-infection remains challenging.Heme oxygenise 1(HO-1) and neopterin have shown to be as potential biomarkers for TB diagnosis. Infection of macrophages with Mycobacterium tuberculosis (M. tb) causes the production o…
S Marimuthu
Background: Tuberculosis Preventive Treatment (TPT) is essential in reducing the risk of progression from latent tuberculosis infection (LTBI) to active disease. However, the factors associated with the non-initiation of TPT have not been explored thoroughly. Objective: This stud…
Rebecca F. Baggaley, Carolin Vegvari, Christian Akem Dimala, Marc Lipman, Robert F. Miller, et al.
…the related manuscript: “Health economic analyses of latent tuberculosis infection screening and preventive treatment among people living with HIV in lower tuberculosis incidence settings: a systematic review”.In a systematic review, the related study assessed cost-effectiveness …
Heinke Kunst, Dominik Zenner, Giovanni Sotgiu
…bold> Kunst H, Zenner D, Sotgiu G. How do migrations affect tuberculosis burden? Tuberculosis control among migrant populations. <italic>In:</italic> García-Basteiro AL, Öner Eyüboğlu F, Rangaka MX, eds. The Challenge of Tuberculosis in the 21st Century (ERS Monograph). Sheffield…
Hyung Woo Kim, Jinsoo Min, Joon Young Choi, Ah Young Shin, Jun‐Pyo Myong, et al.
Abstract Background This study aimed to investigate actual tuberculosis (TB) risk and uptake rates of latent tuberculosis infection (LTBI) screening among eight clinical risk groups specified in Korean guidelines. Proportions of potentially preventable TB in these groups were als…
Sindhura Lakshmi Koulmane Laxminarayana, Sushma Belurkar, Kavitha Saravu, Shilna Muttickal Swaminathan
…on-TB Gold (QFT), are available for the diagnosis of latent tuberculosis infection (LTBI). Intracellular cytokine flow cytometry (ICCFC) can be used to assess T-cell immune responses specific to tuberculosis (TB). We studied the role of ICCFC in differentiating active pulmonary T…
Manvi Singh, Nishant Jaiswal, Shreya Singh, Pranita Pradhan, Amit Agarwal, et al.
Introduction: Tuberculosis is still a leading cause of morbidity and mortality in the world, especially the low and middle income countries. While a lot is being done on the programmatic level, the burden of the disease is still underestimated owing to problems in diagnostics and…
Rita Wahyuningsih, Mei Syafriadi, Diana Chusna Mufida
…T (TPT) as an effort to strengthen the management of latent tuberculosis infection (ILTB) are still low. Toddlers in close contact with Drug Sensitive Tuberculosis (TB SO) are a group at risk of being infected with TB so they need to get TPT. This study aims to determine and anal…
Anish Butani, Akshaya Chauhan, Nitinkumar Solanki
Abstract Background: Tuberculosis preventive treatment (TPT) is important to halt the evolution of latent tuberculosis (TB) infection to active disease in household contacts (HHCs) of TB patients suffering from pulmonary type. Despite the various programmatic efforts, there are s…
Ajoy Kumar Verma, Raj Narayan Yadav, Lokender Kumar, Nawaid Hussain Khan, Ashish Ranjan, et al.
Abstract Introduction: Detecting latent tuberculosis infection (LTBI) is becoming more important in cases where the risk of disease progression is high and where anti-tuberculosis (TB) treatment is necessary. The aim of this study is to find out the immunological evidence of LTBI…
Diakourga Arthur Djibougou, Gloria Ivy Mensah, Tibila Kientega, Leon Tinnoaga Sawadogo, Hervé Hien, et al.
Background: The diagnosis and treatment of active tuberculosis and the detection/management of latent tuberculosis infection (LTBI) cases are the two main strategies for the TB control, particularly in endemic countries. Tuberculin skin test (TST) and Interferon Gamma Release Ass…