Showing 76–100 of 200 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
Rangasamy Ramanthan, M. Jayapritha
…ngs, to improve TB detection. Expanding access to molecular diagnostics and integrating nutritional interventions are essential for better management.
Tehreem Zulfiqar Janjua, Saqib Musharaf, Arooba Zulfiqar Janjua, Faisal Hassan Zahid Chaudhery, Farzeen Bakhtawar, et al.
Pulmonary tuberculosis (PTB) remains a significant public health concern, especially in high-burden countries like Pakistan. Diagnosis becomes particularly challenging in sputum-negative patients, leading to delayed treatment and increased transmission. Bronchoalveolar lavage (BA…
MH Mezzour, M. Karhate, L. Senhaji, M. Taghyioullah, B. Amara, et al.
Abstract RATIONALE: Pseudotumoral tuberculosis (TB), an uncommon malignancy-mimicking form of pulmonary TB, often causes diagnostic delays, especially in patients without TB history or immunosuppression. In TB-endemic areas, reliance on negative sputum culture or GeneXpert result…
S. Lee, Hee Kang, Min-Jung Jung, Sekyoung Park, Ki Nam Lee
Background: This study evaluated the diagnostic yield and positive predictive factors of post-percutaneous core needle biopsy (PCNB) sputum cytology in diagnosing malignancy.Methods: This retrospective study included patients who underwent PCNB at a single center from January 201…
World Health Organization
This operational handbook provides practical guidance for the implementation of WHO policies and recommendations on rapid diagnostic technologies for tuberculosis (TB) and drug-resistant tuberculosis (DR-TB). The publication describes WHO-recommended diagnostic tests and testing …
І. В. Ліскіна, С. Д. Кузовкова, Л. М. Загаба, О.D. Nikolaeva
… diagnosed in 13 % of cases. The main methods of laboratory diagnostics were classical bacteriological methods — simple direct light microscopy and MBT culture, the positive results of which were obtained in only half of all studies, as well as molecular-genotypic tests. Prevalen…
Rina Triasih
In general, the diagnosis of COVID-19 in children is the same as that in adults, which is based on the clinical and epidemiological history of the patient. Clinicians should have a suspicion of COVID-19 when a child shows one or more clinical manifestations of COVID-19 and, withi…
Bjørn Waagsbø, Eva Margrethe Buset, Jørn-Åge Longva, Merete Bjerke, Birgitte Bakkene, et al.
PURPOSE: Studies on aetiology of community-acquired pneumonia (CAP) vary in terms of microbial sampling methods, anatomical locations, and laboratory analyses, since no gold standard exists. In this large, multicentre, retrospective, regional study from Norway, our primary object…
Nur Azikin Rozali, Ayu Mustikarini
Introduction: Pulmonary tuberculosis (TB) poses a significant global health challenge, necessitating timely and accurate diagnosis. While chest X-ray (CXR) is widely used, its diagnostic accuracy varies. Advanced modalities like computed tomography (CT) and ultrasound offer poten…
Bjørn Waagsbø, Eva Margrethe Buset, Jørn-Åge Longva, Merete Bjerke, Birgitte Bakkene, et al.
Abstract PurposeStudies on aetiology of community-acquired pneumonia (CAP) vary in terms of microbial sampling methods, anatomical locations, and laboratory analyses, since no gold standard exists. In this large, multicentre, retrospective, regional study from Norway, our primary…
François Chappuis, MD, PhD
Tropical fevers have been a diagnostic challenge from the antiquity. Nowadays, despite the availability of good diagnostic capacities, undifferentiated febrile illnesses continue to be a thorny problem for travel physicians. In developing countries, the scarcity of skilled person…
Dr Natasha Naseer
Background: Pulmonary tuberculosis (TB) remains a major global health concern, particularly in high-risk populations such as immunocompromised individuals, children, and close contacts of TB patients. While chest X-ray (CXR) is the conventional screening tool, its sensitivity is …
Nsikak Godwin Etim, Tatfeng Youtchou Mirabeau, Olwayemisi A. Olorode, Miriam U. Nwodo, Sylvester Chibueze Izah
Various diagnostic methods are employed to detect tuberculosis (TB).One of the most commonly used tools is the microscopic examination of sputum samples, utilizing acid-fast staining to identify Mycobacterium tuberculosis.Chest X-rays are instrumental in identifying TB-related lu…
Raju Sarkar, Medha Wadhwa, Dhaval Parmar, Apurvakumar Pandya, Devang Raval, et al.
Introduction: Tuberculosis (TB) continues to be a major worldwide health concern, which is the leading cause of death in nations like India. Despite various efforts to combat TB, effective screening and timely diagnosis remain challenging. The use of Artificial Intelligence (AI) …
Dr Takasur Bibi
Female genital tuberculosis (FGTB) is a significant but often underdiagnosed cause of infertility and chronic pelvic morbidity, particularly in developing countries. Conventional diagnostic methods, such as histopathology, often suffer from low sensitivity due to the paucibacilla…
Suganthi P, Twinkle Dhamecha, Nilam Patel, Vinod Kumar
Background: Bronchial biopsy remains the reference standard for diagnosing pulmonary pathology; however, minimally invasive cytological techniques are increasingly used in clinical practice. This study aimed to determine the diagnostic accuracy of sputum cytology, bronchoalveolar…
K.K. Chopra, Shweta Singh
…says. The program envisages correlating the rapid molecular diagnostics, which offers an impressive turnaround time of as low as around 2 h, with conventional standard methods to reinforce the diagnostic capacities. These also provide with august identification of drug resistance…
Hidayat, Muhammad Dafa, Mertaniasih, Ni Made, Yudhawati, Resti
…is of laboratory confirmation methods for tuberculosis (TB) diagnostics. It encompasses historical perspectives and contemporary advancements, offering insights into the evolution of TB diagnosis over time. The review focuses on three primary diagnostic methods: microscopic exami…
Anu Jain, Snigdha Sen, Mahipal Singh, Fatima Abbas, Geetika Kriti Vashishtha, et al.
… analyzed peer-reviewed studies reporting OTB epidemiology, diagnostics, and clinical manifestations. Eleven studies from high-burden regions (India, Pakistan, China, Malaysia) and the USA were included after database searches and application of eligibility criteria. Due to heter…
Mohammed Suhail Najm Al-Salam, Farah Akram Mohammed Al-Mahdawi, Ahmed Shakir Ali Al-Wassiti, Mohammed Tareq Mutar
• Sensitivity, specificity, and AUROC analyses confirmed the criteria’s ability to reliably distinguish presumed ocular tuberculosis from non-tuberculous uveitis. • The structured use of mandatory and supportive criteria improved diagnostic consistency and reduced misdiagnosis in…
Hidayat, Muhammad Dafa, Mertaniasih, Ni Made, Yudhawati, Resti
…is of laboratory confirmation methods for tuberculosis (TB) diagnostics. It encompasses historical perspectives and contemporary advancements, offering insights into the evolution of TB diagnosis over time. The review focuses on three primary diagnostic methods: microscopic exami…
H Sekharamahanti, D Nerusu, K Chintharala, L Dankwa
Abstract Rationale Patients with a strong clinical suspicion of pulmonary tuberculosis (PTB) but negative initial spot CBNAAT (GeneXpert) results present a common diagnostic dilemma. Simple, low-cost sampling approaches such as induced sputum or 24-hour pooled sputum may enhance …
Laura Olbrich, Heather J. Zar, Steve Graham, Issa Sabi, Nyanda Elias Ntinginya, et al.
…ry confirmation is hampered by non-specificity of symptoms. Diagnostics validation studies in children are difficult – in most studies, very few of the symptomatic children achieved microbiological disease confirmation, resulting in imprecise estimates for test sensitivity. Desig…
Amy Y Vittor, MD PHD
Tuberculosis (TB) is one opportunistic infection often seen in HIV individuals. In 2013, there were an estimated 31,800 HIV-TB co-infection cases and 6,100 HIV-related deaths due to TB in the Americas. Due to the non-specific nature of its clinical symptoms, TB can be confused wi…
Qiao Liu, Dandan Yang, Ye Ji, Leonardo Martínez, Jianming Wang, et al.
…y hampered by inadequate diagnostic tools and point-of-care diagnostics are urgently needed. Recent work has highlighted C-reactive protein (CRP) as a potential supplementary tool however its reliability is still unclear. Methods: We performed an age- and sex-matched case-control…