Showing 51–75 of 200 documents
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Renuka Murhar, Sunita Gajbhiye, S.S. Zodpey, Shailesh Lichade
…lones indicating pre-XDR TB. Conclusions: For Mycobacterium tuberculosis detection in extrapulmonary samples, multiple modalities should be employed so that the bacilli in these samples is not missed and the turn-around time is lowered which is a key to TB control strategy.
Pooja Sadana, Vishal Verma, Priyanka Devgun
…reatment outcome. Other factors like sex, residence, typeof tuberculosis and the HIV status of the patient did not affect the treatment outcome.
Pooja Sadana, Vishal Verma, Priyanka Devgun
…eatment outcome. Other factors like sex, residence, type of tuberculosis and the HIV status of the patient did not affect the treatment outcome.
Argita D. Salindri, Maia Kipiani, Nino Lomtadze, Nestani Tukvadze, Zaza Avaliani, et al.
…e relationship between common comorbidities in persons with tuberculosis (TB) (including human immunodeficiency virus [HIV], diabetes, and hepatitis C virus [HCV]) with post-TB mortality. We conducted a retrospective cohort study among persons who initiated treatment for rifampic…
Manisha Nagpal, Sarthak Chawla, Priyanka Devgun, Naresh Chawla
Background: Multidrug resistant tuberculosis (MDR-TB) has become a major public health problem. It is associated with significant morbidity and mortality. The treatment success rate worldwide is around 50%.Methods: This cross-sectional study was conducted on all MDR-TB patients w…
World Health Organization. Regional Office for Europe
…arming problem of multidrug- and extensively drug-resistant tuberculosis (M/XDR-TB) in the WHO European Region, and in order to scale up a comprehensive response and to prevent and control M/XDR-TB, a consolidated action plan has been developed for 2011–2015 for all 53 Member Sta…
Human Sciences Research Council
…'s population of the human immunodeficiency virus (HIV) and tuberculosis (TB) co-infected individuals. It has been estimated that approximately 60% of people with TB are co-infected with HIV (WHO 2012). Co-infected individuals have almost double the chances of getting multi-drug …
Zubeida Salaam-Dreyer, Elizabeth M. Streicher, Frederick A. Sirgel, Fabrizio Menardo, Sònia Borrell, et al.
Abstract Rifampicin mono-resistant TB (RMR-TB) constitutes 38% of all rifampicin-resistant TB (RR-TB) in South Africa and is increasing. We aimed to compare RMR-TB with multidrug-resistant TB (MDR-TB) within a high TB, RR-TB and HIV burden setting. Patient-level clinical data and…
Zumla, Alimuddin, Wallis, Robert, Klein, Nigel, Oleson, Ole, Lang, Hannu, et al.
Xiaowei Dai, Chung‐Yi Li, N H Wang, S S Chen, Li Tian, et al.
The prevalence of fluoroquinolones (LFX and MFX) resistance in rifampicin-resistant MTB is very serious. LFX and MFX show incomplete bidirectional cross-resistance. BDQ and LZD have the most promising future in the treatment of MDR-TB. Improve drug-resistance testing will help to…
H J Chen, Xubin Zheng, Y Wang, Jinze Li, Biao Xu
Number of patients under drug resistance surveillance and the detection of MDR/XDR-TB trended to increase in Guizhou province from 2012 to 2019. The detection rate of MDR/XDR-TB in high-risk groups was higher than low-risk groups.
Pavithra GB, R. Prassanna Adithiyan, B Charumathi, Timsi Jain
Background: Non- adherence is one of the major risk factors for the emergence of MDR and XDR TB. It is also one of the key factors responsible for treatment failure, disease relapse, prolonged infection and death. This study was conducted to explore the various factors contributi…
World Health Organization. Regional Office for the Eastern Mediterranean
World Health Organization
Elwira Sieniawska
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Despite the successes in the development of diagnosis and treatment of this disease, it still poses a significant threat to humanity, especially in countries with an average and low level of healthcare de…
Hamidah Hussain, Amyn A. Malik
Preventing tuberculosis infection from progressing to tuberculosis disease is a crucial component of the goal to eliminate tuberculosis. When deciding on the use of tuberculosis preventive therapy among household contacts, policy makers regularly ask questions, such as whether tu…
Christoph Lange, Anca Vasiliù, Anna M. Mandalakas
Tuberculosis is the leading cause of death attributed to a single infectious pathogen worldwide. Despite the availability of anti-tuberculosis therapies for more than half a century, the number of people affected by tuberculosis reached a historical peak in 2021.1WHOGlobal tuberc…
Yue Wang, Weibing Wang
Given that existing tuberculosis interventions and strategies are not going to enable achievement of WHO's goal to eliminate tuberculosis by 2050,1Xu K Ding C Mangan CJ et al.Tuberculosis in China: A longitudinal predictive model of the general population and recommendations for …
Beijing Hospital
Background: Drug resistant tuberculosis is a serious public health problem that threatens the health of human life and the development of society and economy. At present, the diagnosis of drug-resistant tuberculosis mainly depends on traditional drug susceptibility test. But it …
Michael Reid, Eric Goosby, Sebastian Kevany
…r High-Level Meeting of all UN member states made defeating tuberculosis a global political priority.1Stop TB PartnershipUN high-level meeting on TB–key targets and commitments.http://www.stoptb.org/global/advocacy/unhlm_targets.aspDate: 2018Date accessed: December 12, 2018Google…
Pradeep M Muragundi
Introduction: Extensively Drug-Resistant Tuberculosis (XDR-TB) is a recent challenge for tuberculosis control program. The absence of the functional drugs and high rate of the failure in treatment and mortality rate also high jeopardize for epidemiology. Its prevalence is unknown…
Gunar Günther, Lorenzo Guglielmetti, Claude Leu, Christoph Lange, Frank van Leth, et al.
…ckground Access to comprehensive diagnostics and novel anti-tuberculosis medicines is crucial to improve tuberculosis control at times of emerging Mycobacterium tuberculosis drug resistance. Methods We investigated access to genotypic and phenotypic M tuberculosis drug susceptibi…
Victor Næstholt Dahl, Simon Tiberi, Delia Goletti, Christian Wejse
… countries healthcare systems will be strained. Even though tuberculosis (TB) incidence rates had been gradually decreasing over the years in Ukraine and Russia with rates of 73 and 46 per 100,000 individuals in 2020 (WHO 2021WHOGlobal tuberculosis report 2021. World Health Organ…
Christoph Lange, Keertan Dheda, Dumitru Chesov, Anna M. Mandalakas, Zarir Udwadia, et al.
…lopment and in implementation, to reduce the drug-resistant tuberculosis epidemic.1Lange C Dheda K Chesov D Mandalakas AM Udwadia Z Horsburgh Jr, CR Management of drug-resistant tuberculosis.Lancet. 2019; 394: 953-966Summary Full Text Full Text PDF PubMed Scopus (128) Google Scho…
Nawal Salahuddin, MBBS,FCCP
Tuberculosis is a global public health problem. One third of the world's population is infected with tuberculosis (TB) with almost 2 million deaths per year globally. According to the WHO, Pakistan ranks 8th amongst the 22 high TB burden countries, with an estimated prevalence is…