Showing 26–50 of 200 documents
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Sumona Datta, Carlton A. Evans
Tuberculosis is estimated to affect 10 million people each year, but this statistic is remarkably uncertain: 30% are countries' estimates of undiagnosed, untreated, or unreported cases. Furthermore, about half of tuberculosis diagnoses globally are uncertain because they rely ent…
Marc d’Elbée, Nyashadzaishe Mafirakureva, Chishala Chabala, Minh Huyen Ton Nu Nguyet, Martin Harker, et al.
…ute malnutrition (SAM) are an important risk group for underdiagnosis and death from tuberculosis. In 2022, the World Health Organization (WHO) recommended use of treatment decision algorithms (TDAs) for tuberculosis diagnosis in children. There is currently no cost-effectiveness…
Özlem Tezol
Objectives: Pediatric tuberculosis is a major public health problem. Malnutrition characterized with wasting is prevalent among pediatric tuberculosis patients. We aimed to review pediatric tuberculosis cases by considering their nutrition manifestations. Materials and Methods: T…
Christiane Mello Schmidt, Claudete Aparecida Araújo Cardoso, Rafaela Baroni Aurílio, Maria de Fátima Bazhuni Pombo Sant’ Anna, Clemax Couto Sant’Anna
As children develop paucibacillary forms of tuberculosis (TB), bacteriological tests usually are negative. This chapter describes aspects of the laboratory tests available for clinical practicePractice. It also discusses perspectives, such as biomarkers, which can be utilized in …
Constantin Iavorschi, Stela Kulcitkaia, Igor Ivanes, Nadejda Pisarenco
Pediatric tuberculosis (TB) presents unique diagnostic challenges due to various factors, including the low sensitivity of sputum examination, difficulties in obtaining samples, and the presence of paucibacillary forms of the disease. This retrospective-descriptive study aimed to…
Maria Eugênia Julio, Alexandra Monteiro, Mônica de Cássia Firmida, Diego Rodrigues Tavares, Ana Josiele Ferreira Coutinho
Pulmonary tuberculosis in childhood is difficult diagnosis taking into account the difficulty of microbiological confirmation, being diagnosis based on the presence of clinical signs, radiological alterations, history of contact with a bacilliferous adult, and interpretation of t…
Tulane University
Pediatric tuberculosis (TB) continues to pose diagnostic challenges in low- and middle-income countries with high rates of TB disease, due to the well-described impact of paucibacillary disease in children, and current TB culture and polymerase-chain reaction tests are of limited…
Shrinivasa B. Marinaik, Sriram Selvaraju, R. Srinivasan, Krishnamoorthy, Sunil Kumar Raina, et al.
Background: About one-fifth of the global gap in TB diagnosis was contributed by India which translates to roughly over half a million cases. Meanwhile the National tuberculosis elimination programme has made coordinated efforts to involve public and private health providers in a…
Krunal Patel, Kinjal Patel, Pooja Gandhi, Bhavini Rathwa, Dipak M. Nakum
Introduction: Tuberculosis is a chronic infectious disease caused by predominantly Mycobacterium tubercle bacilli. Pediatric tuberculosis is among the top 10 causes of death in children. India accounts for one fourth of the global tuberculosis burden, standing one among the thirt…
Aybüke Akaslan Kara, Kamile Ötiken Arıkan, Elif Böncüoğlu, Elif Kıymet, Şahika Şahinkaya, et al.
…we aimed to evaluate the approaches and knowledge levels of pediatric infectious diseases research workers and pediatricians in the diagnosis and treatment of tuberculosis under the guidelines updated by the Ministry of Health in 2019. Method: This survey is a descriptive study a…
Emad Siddiqui, Tooba Siddiqui, Abdus Salam Khan
Abstract Background Tuberculosis (TB), a preventable airborne infectious disease, early detection is essential to improve health outcomes. Extent of childhood tuberculosis is unknown and is estimated to be around 6% of all incidences. Diagnosis of pediatric tuberculosis is always…
Olesya Pankratova
Tuberculosis is one of the 10 leading causes of death in the world. According to the WHO global strategy, one of the health targets of the Sustainable Development Goals is to end the tuberculosis epidemic by 2030. The article summarizes the basic theoretical data from various pro…
Francesca Montagnani, PhD, MD
…T, Cellestis Limited, Carnegie, Victoria, Australia) in the diagnosis of tuberculosis (TB - active or latent) in pediatric subjects (0 and 17 year)s recently exposed to infection (indicated as "contacts") or with clinical suspicion of active TB, and to compare the results obtaine…
Gagni Coulibaly, Fah Gaoussou Traoré, Bassirou Diarra, Aminata Maïga
<h3>Background</h3> The diagnosis of childhood tuberculosis is still a challenge in the world because children are generally paucibacillary moreover obtaining sputum is very difficult. Most of the existing diagnostic tests for tuberculosis are based on sputum sampling in symptoma…
John Cherry
… Summary This preprint examines the time from completion of tuberculosis preventive therapy to later TB diagnosis among people living with HIV on ART in Eastern Uganda. The study uses routine program data from three TASO Centres of Excellence in Mbale, Soroti, and Tororo and incl…
John Cherry
… Summary This preprint examines the time from completion of tuberculosis preventive therapy to later TB diagnosis among people living with HIV on ART in Eastern Uganda. The study uses routine program data from three TASO Centres of Excellence in Mbale, Soroti, and Tororo and incl…
Christian Wejse
… al.Point of care Xpert MTB/RIF versus smear microscopy for tuberculosis diagnosis in southern African primary care clinics: a multicentre economic evaluation.Lancet Glob Health. 2019; 7: e798-e807Summary Full Text Full Text PDF PubMed Scopus (27) Google Scholar present a previou…
Devraj Regmi, Purnakala Regmi, Sarbada Shrestha
Background: Delay in the diagnosis of tuberculosis can lead to an increased inactivity period, delayed treatment, and increased disease severity. The objective of this study was to identify the magnitude of the delay and the factors causing a delay in the diagnosis of Tuberculosi…
Pınar Etiz, Ali Tanju Altunsu
…xamine the epidemiologic features and treatment outcomes of pediatric pulmonary tuberculosis cases who were registered to the Adana Tuberculosis Dispensaries. Materials and Methods: Fifty-six pediatric patients aged 0-18 years with the diagnosis of pulmonary tuberculosis were exa…
Salih Cesur
Tuberculosis is an infectious disease whose diagnosis dates back to very early ages, which still maintains its importance in the world and in our country, can be treated and prevented with preventive (prophylactic) treatment. It is one of the leading causes of death in HIV/AIDS p…
Christian Diamant Mossoro‐Kpinde, Honorat Nouzoukem, Marcel Mbeko Simaléko, Nina Esther Ngoyi Ontsira, Hermione Dahlia Mossoro-Kpinde, et al.
Background and Objective: Tuberculosis is one of the leading causes of morbi-mortality, especially in developing countries, due to delayed diagnosis and management. The goal of this study is to assess the contribution of lipoarabinomannan (LAM) in improving tuberculosis (TB) diag…
Ayling Sanjaya
The diagnosis of pediatric TB is based on history taking, clinical symptoms, physical examination and support. In recent years the role of microRNA (miRNA or miR) has become a concern for researchers as biomarkers of diagnosis and therapy in TB in adults and children. MicroRNA is…
Santiago Atehortúa-Muñoz, Andrea Cardona-Moreno, Laura Niño-Quiroga, Javier Orlando Contreras-Ortiz, Catalina Arango-Ferreira
Abstract Objective Diagnosis of pulmonary tuberculosis (PTB) in pediatrics is a challenge due to the paucibacillary condition of the disease in this population, low sputum expectoration, and diverse unspecific symptomatology. Mycobacterial isolation through culture remains a prio…
Dhruv Gandhi, Meenakshi Dey, Sonal Patil, Dhruv Mamtora, Ira Shah
Abstract Background The diagnosis of pediatric tuberculosis (TB) remains challenging due to difficulties in specimen collection and the paucibacillary nature of the disease. While Mycobacteria Growth Indicator Tube (MGIT) culture is the gold standard, its long turnaround time lim…
Wiwiek Setiowulan, redi rulandani, Helmy Rachman
Pediatric drug reaction with eosinophilia and systemic symptoms (DRESS) is a life-threatening uncommon disease that can be difficult to diagnose. We present a case of a 10-year old girl with ten days of high fever during her fifth week of ATT (consisting of isoniazid, rifampicin,…