Showing 1–25 of 200 documents
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Laura Olbrich, Leyla Larsson, Rory Dunbar, Peter J Dodd, Megan Palmer, et al.
…* In 2023, almost 200,000 children under 15 years died from tuberculosis, most without appropriate treatment. Treatment decision algorithms (TDAs), developed to facilitate rapid anti-tuberculosis treatment initiation in children, were recommended by the World Health Organization …
Peter Scott, Maysa Elsayedkarar, Edson Marambire, Gertrude Ncube, Tsitsi Apollo, et al.
**BACKGROUND:** Tuberculosis household contacts are at elevated risk of HIV, and systematic screening for tuberculosis is an opportunity for people to know their status. We aimed to assess the coverage and positivity of HIV testing during household systematic screening for tuberc…
M Deepaselvi, C Ammaiyappan Palaniswamy, Santhi Sree Mummadisingu, Sai Chandhan Throvagunta, Kavatarapu Pradyumna, et al.
…nufacturing. Silicosis not only increases susceptibility to tuberculosis (TB) infection but also adversely impacts TB outcomes. Despite the long-established association between silicosis and TB, a clear understanding of the burden within the Indian context has remained unexplored…
Helen Zhang, Naomi Medina-Jaudes, Alicia Forcada-Nadal, Ewan M Harrison, Francesc Coll
**BACKGROUND:** Tuberculosis (TB) is the leading cause of death from an infectious disease worldwide. Mutations arising in Mycobacterium tuberculosis complex (MTBC) strains during TB infection provide a record of bacterial adaptations, such as those needed to survive the attack o…
Abraham Tekola Gebremedhn, Kidist Bobosha, Hawult Taye Adane, Yeabsira Alemu Fantaye, Dawit Girma Abebe, et al.
**BACKGROUND:** Post-tuberculosis lung disease (PTLD) is a significant global public health challenge. The contribution PTLD on long-term morbidity and impaired quality of life is increasingly recognized. There is limited evidence on effective management strategies of PTLD. This …
Harri Hardi, Zahra Fitrianti, Liganda Endo Mahata, Melva Louisa
… complicated therapeutic challenges, such as the coinfected Tuberculosis (TB)-HIV population. This systematic review analyses pharmacogenes related to antiretroviral and anti-tuberculosis medications in the TB-HIV population. An analysis of 39 included studies indicated that efav…
Janmejaya Samal, Hari Singh
**BACKGROUND:** Delayed tuberculosis (TB) care can have adverse effects on both patients and the community. Such delays can perpetuate transmission within the community and disrupt ongoing efforts to eliminate TB. **OBJECTIVES:** The primary objective of this meta-analysis was t…
Aninda Debnath, Ravindra Nath, Anubhav Mondal, Pankaj Chandrabhan Nathe, Jugal Kishore, et al.
Tuberculosis (TB) and tobacco use are two intertwined public health challenges that significantly impact low- and middle-income countries, particularly India, which bears the highest global TB burden. Tobacco use exacerbates TB risk, progression, and treatment outcomes. Despite t…
Maham Zahid, Saima Afaq, Kashif Shafique, Fatima Khalid Qazi, Urooj Ashfaq, et al.
**INTRODUCTION:** Tuberculosis (TB) and diabetes mellitus comorbidity can lead to poor TB treatment outcomes, particularly with uncontrolled blood glucose levels. Understanding the impact of glycemic control on TB treatment outcomes is essential. **OBJECTIVE:** To synthesise evi…
Anna Juul Christensen, Laura Risbjerg Omann, Jessica Carlsson, Joseph Baruch Baluku, Ole Kirk, et al.
… substance and hazardous alcohol use in people with HIV and tuberculosis (TB) disease and its impact on TB treatment outcomes. **METHODS:** A systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched MEDLI…
Alfred Ngwira, Samuel Manda, Esron Daniel Karimuribo, Sharadhuli Iddi Kimera
**BACKGROUND:** Tuberculosis (TB) in cattle negatively affects the cattle economy in Africa, with zoonotic TB posing drug-resistance issues in humans. The burden of TB in cattle and zoonotic TB in humans in sub-Saharan Africa (SSA) is not well understood. This study aimed to dete…
Dereje Dana Zeruma, Mesfin Kote, Eshetu Zerihun, Getahun Gedabo, Biruk Wogayehu
**INTRODUCTION:** The WHO’s 2024 Global tuberculosis (TB) Report shows that TB causes 1.25 million deaths annually, including 161,000 TB-Human Immunodeficiency Virus (HIV) infections. It affects 10.6 million people, mainly in Asia and Africa, 75% of whom are…
Janmejaya Samal, G S Preetha, Hari Singh
**BACKGROUND:** Delayed diagnosis and treatment can be detrimental not only to patients but also to the community, as such delays can perpetuate TB transmission. This presents a significant challenge in the ongoing efforts to eliminate TB from the community. The primary objective…
Leeberk Raja Inbaraj, Mukesh Kumar Sathya Narayanan, Jefferson Daniel, Vignes Anand Srinivasalu, Adhin Bhaskar, et al.
**BACKGROUND:** Accurate and prompt diagnosis of tuberculosis in children is challenging due to non-specific clinical presentation and the low bacillary load of samples. Low-complexity manual nucleic acid amplification tests (LC-mNAATs) such as loop-mediated isothermal amplificat…
David J Horne, Jerry S Zifodya, Adrienne E Shapiro, Elizabeth Chandler Church, Jonah S Kreniske, et al.
…commended rapid diagnostic test that simultaneously detects tuberculosis and rifampicin resistance. This review updates a comparative accuracy Cochrane review of Xpert MTB/RIF and Xpert Ultra as Xpert Ultra has replaced Xpert MTB/RIF. **OBJECTIVES:** To determine the diagnostic …
Stephanie Bjerrum, Bada Yang, Johanna Åhsberg, Laura Olbrich, Mathias Weis Damkjær, et al.
…gnostic tests (also known as mWRDs) widely used to diagnose tuberculosis disease. The lateral flow urine lipoarabinomannan assay (LF-LAM) is recommended by the WHO to assist in diagnosing tuberculosis disease amongst people with HIV. Previous systematic reviews have assessed the …
Hannah M Rickman, Mphatso D Phiri, Helena R A Feasey, Maria Krutikov, Hui Shao, et al.
**BACKGROUND:** Tuberculosis killed 1·25 million people globally in 2023. Men have a 1·7 times higher tuberculosis incidence than women, but it is not known to what extent this discrepancy is driven by greater exposure to Mycobacterium tuberculosis. We aimed to analyse …
Ana Luíza Brasileiro Nato Marques Assumpção, Flávia Correia Silva, Licia Kellen de Almeida Andrade, Quézia Rosa Ferreira, Gilberto da Cruz Leal, et al.
…men's experiences in the process of illness and care during tuberculosis treatment. A systematic review of qualitative studies was conducted based on the Joanna Briggs Institute's Manual for Evidence Synthesis and the Preferred Reporting Items for Systematic Review and Meta-Analy…
Wagaw Abebe, Solomon Gedifie, Tadele Emagneneh
**BACKGROUND:** Tuberculosis is one of infectious disease, which caused by. It is still one of the major problems threatening public health worldwide. However, there are inadequate systematic studies and statistical assessments of tuberculosis prevalence, mainly in Ethiopia. **O…
Laura Olbrich, Bada Yang, Hayley Poore, Alia Razid, Brittney Sweetser, et al.
…ts (LC-aNAATs) are molecular assays widely used to diagnose tuberculosis disease in children. The lateral flow urine lipoarabinomannan assay (LF-LAM) is recommended for use amongst children with HIV. Previous systematic reviews have assessed the diagnostic accuracy of LC-aNAATs a…
P Jamshidi, B Danaei, M Arbabi, B Mohammadzadeh, F Khelghati, et al.
… and may accompany the development of various diseases like tuberculosis, cancer, or autoimmune diseases. The term silico-tuberculosis describes a condition in which an individual is affected by both silicosis and tuberculosis at the same time. This systematic review and meta-ana…
Nyashadzaishe Mafirakureva, Anna Cartledge, Isobella Bradshaw, Adrie Bekker, Nicole Salazar-Austin, et al.
…spite known maternal, perinatal, and infant health risks of tuberculosis during pregnancy, global estimates of incidence remain scarce. Existing estimates are outdated, and do not include the postpartum period, HIV co-infection, age, or specific changes in risk, limiting our unde…
Jiahao Meng, Xi Li, Yilin Xiong, Yumei Wu, Pan Liu, et al.
… supplementing vitamin D in the prevention and treatment of tuberculosis infection through a meta-analysis of randomized controlled trials. **METHODS:** The databases of PubMed, Cochrane Library, Embase, and Web of Science were systematically searched from inception to April 21,…
Sheng Liu, Tianyu Lin, Yanyu Pan
…ulation, prompting interest in its potential for preventing tuberculosis. However, clinical findings regarding its protective effects against tuberculosis infection and disease remain inconsistent. We conducted a systematic review and meta-analysis of randomized controlled trials…
James Greenan-Barrett, Simon C Mendelsohn, Thomas J Scriba, Mahdad Noursadeghi, Rishi K Gupta
…ripts provide similar accuracy for detection of subclinical tuberculosis to multi-gene signatures and benchmark their accuracy and clinical utility against interferon-γ release assays (IGRAs). **METHODS:** For this individual participant data meta-analysis, we searched Pub…