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Pranav Shivashankar, Praween Senanayake, Thomas Stephen Ledger, Nicholas Ngui
…DS:** Reports describing confirmed TTA, specified treatment regimens and clinical outcomes were systematically identified and synthesised from PubMed, Embase, Web of Science and Google Scholar from the period 1990 to 2025. Studies with suspected but unconfirmed cases were exclude…
Andrea Llamas-Lopez, James A Seddon, Felicia C Chow, Caryn M Upton, Sanjay K Jain, et al.
**BACKGROUND:** Tuberculous meningitis (TBM) remains the deadliest form of tuberculosis. Inadequate penetration of rifampicin and ethambutol into the brain and cerebrospinal fluid (CSF) may contribute to mortality. Over the last decade, research has focused on "intensified" treat…
Mohammed Alsaeed, Khalid Alanazi, Ali Alhamdan, Mohammed Faqihi, Alaa Alibrahim, et al.
…tions in conventional microbiological techniques. Treatment regimens based on macrolides and fluoroquinolones yielded superior therapeutic outcomes, exhibiting lower relapse rates and fewer adverse effects compared with conventional anti-TB therapy. Surgical interventions played …