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Shyamkumar Sriram, Tareq Abualfaraj, Manal Ali Alsharif, Marwa Zalat, Saad Madani Alawfi, et al.
Patients with latent tuberculosis infection are mainly asymptomatic, but they still carry a notable risk of developing active TB, particularly when the host becomes immunosuppressed. Hence, appropriate diagnosis and management for LTBI are essential. Tuberculin skin test (TST) an…
Jelkeba Bali Weyesa, Mengistu Legesse, Balako Gumi, Girmay Medhin, Ketema Tolossa, et al.
…. This highlighted the need to combine QFT tests with other diagnostics. QFT tests had high specificity and NPV, ensuring reliable negative results. However, lower sensitivity reduces PPV, making positive results less definitive. The results also revealed moderate sensitivit…
Felix Bongomin, Ivaan Pitua, Phillip Ssekamatte, Diana Sitenda, Irene Andia-Biraro, et al.
**OBJECTIVES:** Enzyme-linked immunosorbent assay (ELISA)-based QuantiFERON-TB Gold Plus (QFT-Plus ELISA) testing is associated with manual variability and indeterminate results. The transition from QFT-Plus ELISA to chemiluminescent immunoassay (CLIA) for QuantiFERON-TB Gold Plu…
Nyimas Maida Shofa, Nurike Setiyari Mudjari, Rusdiyana Ekawati, Arianti Arianti, Annisa Zahra Mufida, et al.
…reening and isoniazid prophylaxis, revealing false-negative diagnostics and partial chemoprophylaxis protection. These findings highlight the need for region-specific frameworks integrating multimodal screening, targeted prophylaxis and ongoing clinical surveillance. Adalimumab r…