Showing 1–25 of 34 documents
Sorted by hybrid relevance (keyword + semantic via RRF)
M J Nasiri, D R Silva, F Rommasi, M M Zahmatkesh, Z Tajabadi, et al.
…he following keywords were used: tuberculosis, vaccination, vaccines and PTLD. PubMed/MEDLINE and Embase were used as the search engine, focusing on English-language literature only. **RESULTS:** We identified 9 vaccines potentially useful in PTLD. Influenza, pneumococcal and an…
Jiaqi Chen, Weitong Lin, Chaokai Yang, Wenqi Lin, Xinghui Cheng, et al.
Mucosal vaccines, delivered intranasally or via inhalation, are being studied for respiratory infectious diseases like COVID-19 and influenza. These vaccines aim to provide non-invasive administration and strong immune responses at infection sites, making them a promising area of…
Erum Siddiqui, Mohammad Saad Khan, Maliha Khalid, Harshika Khaim Chandani, Umaimah Naeem, et al.
…ace of rising drug-resistant strains and suboptimal current vaccines. It has the potential to address the unmet need for more effective interventions against drug-resistant TB, a growing global health issue that continues to challenge existing treatment options. **OBJECTIVE:** T…
Jiannan Sun, Xu Jin, Haofei Li, Lan Zhou, Ling Jie Cheng, et al.
…systematically review the published economic evaluations of vaccines included in China’s National Immunization Program (NIP), synthesise the current evidence base, and assess their cost-effectiveness. **METHODS:** A comprehensive search was conducted across PubMed, Web of…
Fathima Raahima Riyas Mohamed, Mudasar Nisar, Ismail Saeed, Mohammed Rushdhi Irfan, Ahlaam Khalid, et al.
**INTRODUCTION:** The Bacille Calmette-Guerin (BCG) vaccine is widely administered in countries with high tuberculosis (TB) prevalence to protect against severe forms of childhood TB. Despite its efficacy, the vaccine can lead to adverse effects like BCGosis, a severe but rare co…
Eldy Akhirul Akbar, Tukiran Tukiran, I Gusti Made Sanjaya, Rudiana Agustini, Muhammad Nurrohman Sidiq
…compassing conventional live-attenuated and protein subunit vaccines as well as computationally designed multi-epitope vaccines (MEVs). A comprehensive literature search of PubMed/MEDLINE, Scopus, Web of Science, and Google Scholar for studies published between January 2020 and D…
Takuma Ohnishi, Hiroyuki Wakiguchi, Shingo Ishimori, Naohiro Itoh, Masato Yashiro, et al.
…hed by September 2022. The search results were divided into vaccines or toxoids for diphtheria, pertussis, tetanus, pneumococcus, influenza virus, hepatitis A virus, hepatitis B virus, human papillomavirus, poliovirus, measles virus, mumps virus, rubella virus, varicella zoster v…
Nichola R Naylor, Mateusz Hasso-Agopsowicz, Chaelin Kim, Yixuan Ma, Isabel Frost, et al.
…biotic-resistant infections and the potential for bacterial vaccines to mitigate this burden. **METHODS:** We take healthcare system and labour productivity perspectives. Hospital cost-per-case and length-of-stay estimates were calculated through meta-analyses and reviewing publ…
Praneta Yadav, Arpita Singh, Manju Kumari, Sunil Kumar Verma, Devendra Singh
…ng in late 2019, led to the rapid development of SARS-CoV-2 vaccines, though early availability was limited, and variants like Delta and Omicron impacted their effectiveness. The Bacillus Calmette-Guérin (BCG) vaccine, used to prevent tuberculosis, has attracted interest for…
Shunli Cai, Tianwei Yan, Yutian Yang, Xin Guo, Xiang Li, et al.
**BACKGROUND:** Bacillus Calmette-Guérin (BCG) vaccination is well established for preventing severe tuberculosis (TB) in children; however, its effectiveness in reducing the progression of latent TB infection (LTBI) to active disease remains uncertain, particularly in real-…
D Visca, R Centis, L D'Ambrosio, A Spanevello, L Petrone, et al.
<sec><title>OBJECTIVES</title>The impact of COVID-19 and SARS-CoV-2-vaccination on interferon-gamma release assay (IGRA) indeterminate results is unclear. This mini-review aims to examine whether COVID-19 or SARS-CoV-2-vaccination affects the accuracy of IGRAs by increasing the i…
Shunli Cai, Qingyi Luo, Guozhong Zhou, Xin Guo, Yan Dong, et al.
**OBJECTIVES:** To update the understanding of the effectiveness of the Bacillus Calmette-Guérin (BCG) vaccine in preventing tuberculosis (TB) infection in children. **METHODS:** PubMed, Web of Science, Cochrane, and Embase were searched from their inception to January 12, …
Johnessa Cung, Patihul Husni, Kyung Taek Oh
Tuberculosis (TB) remains a leading cause of morbidity and mortality worldwide, hampered by prolonged, toxic treatment regimens that lead to poor patient adherence and drug resistance, as well as diagnostic tools that lack sensitivity and specificity. This systematic review evalu…
Louis Torracinta, Nino Gogichadze, Rachel Tanner
**INTRODUCTION:** BCG vaccination can have heterologous or non-specific effects (NSE) that confer resistance against pathogens other than its target Mycobacterium tuberculosis, but the underlying mechanisms are not fully understood. **METHODS:** We conducted a systematic review …
Shunli Cai, Yuan Xia, Yingchen Zhou, Yangxuan Lin, Xin Guo, et al.
**BACKGROUND:** The tuberculin skin test (TST), widely used for latent tuberculosis infection (LTBI) screening, shows reduced specificity in Bacillus Calmette-Guérin (BCG)-vaccinated individuals due to antigenic cross-reactivity. We aimed to quantify the impact of BCG vaccin…
Anita Dalal, Gajendra Singh, Akhil K Gupta, Naresh Kumar Kakker, Sonu Kumari
Interleukin-17A (IL-17A), a pro-inflammatory cytokine primarily produced by Th17 cells, has emerged as a pivotal immunological mediator in both protective and pathological processes across different animal species in addition to human beings. Over the past decade, research has ex…
TianYu Lin, Sheng Liu, Yan-Yu Pan
**BACKGROUND:** Tuberculosis (TB) remains a leading global cause of infectious mortality. Accelerating vaccine development requires validated immune correlates of protection (CoPs). Mechanistic studies have long highlighted Th1 cytokines (IFN-γ, IL-2, TNF-α) as crucia…
Syed Hassan Ali, Shanza Shakir, Umais Ahmed Shaikh, Maryam Khalid, Maria Jawed, et al.
… revaccination benefit in high-risk groups and the need for vaccines with proven protective immunity.
Marta Nerini, Anisa Ribani, Stefania Papa, Duccio Cavalieri, Massimiliano Marvasi
…thogenic mycobacteria, supporting the development of drugs, vaccines, and diagnostics without the constraints of BSL-3 laboratories. However, limitations remain-particularly in drug screening with M. smegmatis and the underrepresentation of environmental studies. The use of surro…
Thomas Santo, Matthew Hickman, Frederick L Altice, Jason Grebely, Sophia Taylor, et al.
**BACKGROUND:** People who are incarcerated experience disproportionately high rates of injecting drug use and infectious disease, including HIV, viral hepatitis and tuberculosis. However, comprehensive global data regarding the availability of services that prevent and manage in…
Alon Lazarovich, Randy F Sweis
Non-muscle-invasive bladder cancer (NMIBC) categorizes early-stage urothelial carcinoma that has not invaded the bladder's muscle layer. Although it is initially treatable with transurethral resection, NMIBC has a high risk of recurrence and progression, which necessitates prolon…
Emma C Carter, Victoria Simpson, Tilly Fox, Andrea M Collins, Stephen B Gordon, et al.
**OBJECTIVES:** This systematic review aims to synthesize the best available evidence on antimycobacterial management of Bacille Calmette-Guérin (BCG) infection in hosts without significant immunocompromise. **METHODS:** We performed a systematic review searching Medline, S…
Wiktoria Andryszkiewicz, Maksym Bodziony, Milena Chmielewska, Martyna Kowalczyk, Gabriela Rzońca, et al.
…ese approaches include immunomodulatory agents, therapeutic vaccines and host-directed treatment. Ongoing research offers promising opportunities for future interventions aimed at decreasing the global mortality associated with tuberculosis.
Maja L Brinch, Andrea Palladino, Jeroen Geurtsen, Thierry Van Effelterre, Lorenzo Argante, et al.
**BACKGROUND:** In the fight against antimicrobial resistance, mathematical transmission models have been shown as a valuable tool to guide intervention strategies in public health. **OBJECTIVE:** This review investigates the persistence of modelling gaps identified in earlier s…
Yaquta Nur Mohamud, Wanna Chaijaroenkul, Kesara Na-Bangchang
This systematic review examines the multifaceted roles of γδ T cells in malaria and tuberculosis (TB) with an emphasis on subset-specific dynamics and functional plasticity. In malaria, γδ T cells, particularly Vγ9Vδ2+ cells, are rapidly activa…